About Transcription factor ETV7
Transcription factor ETV7 (ETV7) is a protein
from Homo sapiens identified by UniProt accession
Q9Y603, 341 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Transcription factor ETV7 |
|---|
| UniProt accession | Q9Y603 |
|---|
| Gene | ETV7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 341 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (70)
Diseases linked to this target (Open Targets).
- rheumatoid arthritis · score 0.33
- Eczematoid dermatitis · score 0.32
- platelet count · score 0.31
- allergic rhinitis · score 0.25
- multiple sclerosis · score 0.21
- breast cancer · score 0.10
- leukocyte count · score 0.09
- melanoma · score 0.08
- platelet component distribution width · score 0.07
- mean platelet volume · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y603-F1 | alphafold | PREDICTED | 64.80 | — |
Amino-acid sequence (341 residues)
MQEGELAISP ISPVAAMPPL GTHVQARCEA QINLLGEGGI CKLPGRLRIQ PALWSREDVL HWLRWAEQEY SLPCTAEHGF EMNGRALCIL TKDDFRHRAP SSGDVLYELL QYIKTQRRAL VCGPFFGGIF RLKTPTQHSP VPPEEVTGPS QMDTRRGHLL QPPDPGLTSN FGHLDDPGLA RWTPGKEESL NLCHCAELGC RTQGVCSFPA MPQAPIDGRI ADCRLLWDYV YQLLLDTRYE PYIKWEDKDA KIFRVVDPNG LARLWGNHKN RVNMTYEKMS RALRHYYKLN IIKKEPGQKL LFRFLKTPGK MVQDKHSHLE PLESQEQDRI EFKDKRPEIS P
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