MORF4 family-associated protein 1 (MRFAP1)

About MORF4 family-associated protein 1

MORF4 family-associated protein 1 (MRFAP1) is a protein from Homo sapiens identified by UniProt accession Q9Y605, 127 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	MORF4 family-associated protein 1
UniProt accession	Q9Y605
Gene	MRFAP1
Organism	Homo sapiens
Length	127 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

Abnormal sperm morphology · score 0.01
teratoma · score 0.00
cancer · score 0.00
Myopia · score 0.00
malaria · score 0.00
myopia · score 0.00
melanoma · score 0.00
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y605-F1	alphafold	PREDICTED	81.94	—

Amino-acid sequence (127 residues)

MRPLDIVELA EPEEVEVLEP EEDFEQFLLP VINEMREDIA SLTREHGRAY LRNRSKLWEM DNMLIQIKTQ VEASEESALN HLQNPGDAAE GRAAKRCEKA EEKAKEIAKM AEMLVELVRR IEKSESS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards