SNRPN upstream reading frame protein (SNURF)

About SNRPN upstream reading frame protein

SNRPN upstream reading frame protein (SNURF) is a protein from Homo sapiens identified by UniProt accession Q9Y675, 71 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	SNRPN upstream reading frame protein
UniProt accession	Q9Y675
Gene	SNURF
Organism	Homo sapiens
Length	71 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
Prader-Willi syndrome · score 0.33
neuroticism measurement · score 0.33
PHF-tau measurement · score 0.29
autism spectrum disorder · score 0.18
amblyopia · score 0.06
metabolite measurement · score 0.04
vasculitis · score 0.03
inflammatory biomarker measurement · score 0.02
YKL40 measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y675-F1	alphafold	PREDICTED	51.74	—

Amino-acid sequence (71 residues)

MERARDRLHL RRTTEQHVPE VEVQVKRRRT ASLSNQECQL YPRRSQQQQV PVVDFQAELR QAFLAETPRG G

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards