About Small ribosomal subunit protein mS40
Small ribosomal subunit protein mS40 (MRPS18B) is a protein
from Homo sapiens identified by UniProt accession
Q9Y676, 258 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein mS40 |
|---|
| UniProt accession | Q9Y676 |
|---|
| Gene | MRPS18B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 258 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- visual perception measurement · score 0.03
- monocyte count · score 0.02
- body mass index · score 0.02
- systemic juvenile idiopathic arthritis · score 0.02
- oral squamous cell carcinoma · score 0.01
- Invasive Breast Carcinoma · score 0.01
- cancer · score 0.01
- hepatocellular carcinoma · score 0.01
- breast cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y676-F1 | alphafold | PREDICTED | 82.20 | — |
Amino-acid sequence (258 residues)
MAASVLNTVL RRLPMLSLFR GSHRVQVPLQ TLCTKAPSEE DSLSSVPISP YKDEPWKYLE SEEYQERYGS RPVWADYRRN HKGGVPPQRT RKTCIRRNKV VGNPCPICRD HKLHVDFRNV KLLEQFVCAH TGIIFYAPYT GVCVKQHKRL TQAIQKARDH GLLIYHIPQV EPRDLDFSTS HGAVSATPPA PTLVSGDPWY PWYNWKQPPE RELSRLRRLY QGHLQEESGP PPESMPKMPP RTPAEASSTG QTGPQSAL
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