About Peptidyl-prolyl cis-trans isomerase FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) is a protein
from Homo sapiens identified by UniProt accession
Q9Y680, 222 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase FKBP7 |
|---|
| UniProt accession | Q9Y680 |
|---|
| Gene | FKBP7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- blood protein measurement · score 0.33
- atrioventricular block · score 0.14
- serum alanine aminotransferase measurement · score 0.14
- aspartate aminotransferase measurement · score 0.13
- atrial fibrillation · score 0.09
- electrocardiography · score 0.09
- atrial flutter · score 0.09
- body height · score 0.08
- left ventricular structural measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y680-F1 | alphafold | PREDICTED | 86.92 | — |
Amino-acid sequence (222 residues)
MPKTMHFLFR FIVFFYLWGL FTAQRQKKEE STEEVKIEVL HRPENCSKTS KKGDLLNAHY DGYLAKDGSK FYCSRTQNEG HPKWFVLGVG QVIKGLDIAM TDMCPGEKRK VVIPPSFAYG KEGYAEGKIP PDATLIFEIE LYAVTKGPRS IETFKQIDMD NDRQLSKAEI NLYLQREFEK DEKPRDKSYQ DAVLEDIFKK NDHDGDGFIS PKEYNVYQHD EL
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