About Solute carrier family 22 member 7
Solute carrier family 22 member 7 (SLC22A7) is a protein
from Homo sapiens identified by UniProt accession
Q9Y694, 548 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Solute carrier family 22 member 7 |
|---|
| UniProt accession | Q9Y694 |
|---|
| Gene | SLC22A7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 548 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.56
- systolic blood pressure · score 0.33
- pulse pressure measurement · score 0.31
- smoking status measurement · score 0.22
- calcium measurement · score 0.20
- diastolic blood pressure · score 0.19
- glomerular filtration rate · score 0.18
- hypertension · score 0.16
- mean arterial pressure · score 0.14
- urate measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y694-F1 | alphafold | PREDICTED | 85.03 | — |
Amino-acid sequence (548 residues)
MGFEELLEQV GGFGPFQLRN VALLALPRVL LPLHFLLPIF LAAVPAHRCA LPGAPANFSH QDVWLEAHLP REPDGTLSSC LRFAYPQALP NTTLGEERQS RGELEDEPAT VPCSQGWEYD HSEFSSTIAT ESQWDLVCEQ KGLNRAASTF FFAGVLVGAV AFGYLSDRFG RRRLLLVAYV STLVLGLASA ASVSYVMFAI TRTLTGSALA GFTIIVMPLE LEWLDVEHRT VAGVLSSTFW TGGVMLLALV GYLIRDWRWL LLAVTLPCAP GILSLWWVPE SARWLLTQGH VKEAHRYLLH CARLNGRPVC EDSFSQEAVS KVAAGERVVR RPSYLDLFRT PRLRHISLCC VVVWFGVNFS YYGLSLDVSG LGLNVYQTQL LFGAVELPSK LLVYLSVRYA GRRLTQAGTL LGTALAFGTR LLVSSDMKSW STVLAVMGKA FSEAAFTTAY LFTSELYPTV LRQTGMGLTA LVGRLGGSLA PLAALLDGVW LSLPKLTYGG IALLAAGTAL LLPETRQAQL PETIQDVERK SAPTSLQEEE MPMKQVQN
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