About Chloride intracellular channel protein 4
Chloride intracellular channel protein 4 (CLIC4) is a protein
from Homo sapiens identified by UniProt accession
Q9Y696, 253 residues long.
MolForge cross-references it against 0 known binders and
158 disease associations.
Target properties
| Protein name | Chloride intracellular channel protein 4 |
|---|
| UniProt accession | Q9Y696 |
|---|
| Gene | CLIC4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 253 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (158)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.41
- diastolic blood pressure · score 0.41
- hemoglobin measurement · score 0.40
- systolic blood pressure · score 0.40
- platelet crit · score 0.38
- erythrocyte count · score 0.38
- hematocrit · score 0.38
- heel bone mineral density · score 0.38
- platelet component distribution width · score 0.37
- mean platelet volume · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y696-F1 | alphafold | PREDICTED | 91.71 | — |
Amino-acid sequence (253 residues)
MALSMPLNGL KEEDKEPLIE LFVKAGSDGE SIGNCPFSQR LFMILWLKGV VFSVTTVDLK RKPADLQNLA PGTHPPFITF NSEVKTDVNK IEEFLEEVLC PPKYLKLSPK HPESNTAGMD IFAKFSAYIK NSRPEANEAL ERGLLKTLQK LDEYLNSPLP DEIDENSMED IKFSTRKFLD GNEMTLADCN LLPKLHIVKV VAKKYRNFDI PKEMTGIWRY LTNAYSRDEF TNTCPSDKEV EIAYSDVAKR LTK
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