2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide

C14H12F2N2O3 — CID 107073991

IUPAC2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide
SMILESNc1ccc(O)cc1C(=O)Nc1ccc(OC(F)F)cc1
InChIInChI=1S/C14H12F2N2O3/c15-14(16)21-10-4-1-8(2-5-10)18-13(20)11-7-9(19)3-6-12(11)17/h1-7,14,19H,17H2,(H,18,20)
InChIKeyGUWVUADMDWCATN-UHFFFAOYSA-N
MW294.26 g/mol
LogP2.83
Rot. Bonds4

About 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide

2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide (PubChem CID 107073991) has the molecular formula C14H12F2N2O3 and a molecular weight of 294.26 g/mol. Its IUPAC name is 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide.

Molecular Properties

Compound Name2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide
PubChem CID107073991
Molecular FormulaC14H12F2N2O3
Molecular Weight294.26 g/mol
Exact Mass294.08
IUPAC Name2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide
SMILESNc1ccc(O)cc1C(=O)Nc1ccc(OC(F)F)cc1
InChIInChI=1S/C14H12F2N2O3/c15-14(16)21-10-4-1-8(2-5-10)18-13(20)11-7-9(19)3-6-12(11)17/h1-7,14,19H,17H2,(H,18,20)
InChIKeyGUWVUADMDWCATN-UHFFFAOYSA-N
XLogP2.83
TPSA84.58 Ų
H-Bond Donors3
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500294.26
LogP ≤ 52.83
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 104

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'aniline', 'substructure': 'N/A'}, {'alert_name': 'hydroquinone', 'substructure': 'N/A'}

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Related Compounds

2-chloro-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide
CID 106501367
N-(4-acetamidophenyl)-2-amino-5-hydroxybenzamide
CID 107073912
3-amino-4-bromo-N-[4-(difluoromethoxy)phenyl]benzamide
CID 61093967
methyl 4-[(2-amino-5-hydroxybenzoyl)amino]benzoate
CID 107074324
2-amino-5-methyl-N-(4-propan-2-yloxyphenyl)benzamide
CID 62510532
2-bromo-N-[4-(difluoromethoxy)phenyl]-4-fluorobenzamide
CID 9273476
N-[4-(difluoromethoxy)phenyl]-2-hydroxy-5-iodobenzamide
CID 34273440
2-amino-N-(4-bromo-3-fluorophenyl)-5-hydroxybenzamide
CID 107075499
3-amino-4-chloro-N-[4-(difluoromethoxy)phenyl]benzamide
CID 43328663
N-[4-(difluoromethoxy)phenyl]-2,4-dinitrobenzamide
CID 2315816
2-amino-N-(4-fluoro-3-methylphenyl)-5-hydroxybenzamide
CID 107075174
N-[4-(difluoromethoxy)phenyl]-2-iodo-5-nitrobenzamide
CID 38902692

Frequently Asked Questions

What is the IUPAC name of 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide?
The IUPAC name of 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide (CID 107073991) is 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide.
What is the SMILES notation for 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide?
The canonical SMILES for 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide is Nc1ccc(O)cc1C(=O)Nc1ccc(OC(F)F)cc1.
What is the InChIKey of 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide?
The InChIKey is GUWVUADMDWCATN-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H12F2N2O3/c15-14(16)21-10-4-1-8(2-5-10)18-13(20)11-7-9(19)3-6-12(11)17/h1-7,14,19H,17H2,(H,18,20).
What are the key properties of 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide?
2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide has a molecular weight of 294.26 g/mol, XLogP of 2.83, 4 rotatable bonds, 3 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide is sourced from PubChem (CID 107073991), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).