N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide

C14H16N4O3 — CID 107374016

IUPACN-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide
SMILESCNc1cnc(C(=O)Nc2cc(OC)ccc2OC)cn1
InChIInChI=1S/C14H16N4O3/c1-15-13-8-16-11(7-17-13)14(19)18-10-6-9(20-2)4-5-12(10)21-3/h4-8H,1-3H3,(H,15,17)(H,18,19)
InChIKeyJFEWNMRLAZVXAA-UHFFFAOYSA-N
MW288.31 g/mol
LogP1.79
Rot. Bonds5

About N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide

N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide (PubChem CID 107374016) has the molecular formula C14H16N4O3 and a molecular weight of 288.31 g/mol. Its IUPAC name is N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide.

Molecular Properties

Compound NameN-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide
PubChem CID107374016
Molecular FormulaC14H16N4O3
Molecular Weight288.31 g/mol
Exact Mass288.12
IUPAC NameN-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide
SMILESCNc1cnc(C(=O)Nc2cc(OC)ccc2OC)cn1
InChIInChI=1S/C14H16N4O3/c1-15-13-8-16-11(7-17-13)14(19)18-10-6-9(20-2)4-5-12(10)21-3/h4-8H,1-3H3,(H,15,17)(H,18,19)
InChIKeyJFEWNMRLAZVXAA-UHFFFAOYSA-N
XLogP1.79
TPSA85.37 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds5
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500288.31
LogP ≤ 51.79
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

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Related Compounds

5-anilino-N-(2,5-dimethoxyphenyl)pyrazine-2-carboxamide
CID 109289572
5-(2,4-difluoroanilino)-N-(2,5-dimethoxyphenyl)pyrazine-2-carboxamide
CID 109293895
5-(2,5-dimethoxyanilino)-N-(2,4-dimethylphenyl)pyrazine-2-carboxamide
CID 109290731
5-(1,3-benzodioxol-5-ylamino)-N-(2,5-dimethoxyphenyl)pyrazine-2-carboxamide
CID 109293894
N-(2,5-dimethoxyphenyl)isoquinoline-3-carboxamide
CID 110860541
5-(2,5-dimethoxyanilino)-N-(2,6-dimethylphenyl)pyrazine-2-carboxamide
CID 109291247
N-(3-chloro-2-methylphenyl)-5-(2,5-dimethoxyanilino)pyrazine-2-carboxamide
CID 109292936
N-(2,5-dimethoxyphenyl)-5-[(1,1-dioxothiolan-3-yl)amino]pyrazine-2-carboxamide
CID 109285300
N-(2,5-dimethoxyphenyl)-5-[2-(2-fluorophenyl)ethylamino]pyrazine-2-carboxamide
CID 109284387
N-(2,5-dimethoxyphenyl)-5-(propan-2-ylamino)pyridine-2-carboxamide
CID 109179771
5-(cyclopropylamino)-N-(2,4-dimethoxyphenyl)pyrazine-2-carboxamide
CID 109271885
5-(2,5-dimethoxyanilino)-N-(3-fluorophenyl)pyrazine-2-carboxamide
CID 109293907

Frequently Asked Questions

What is the IUPAC name of N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide?
The IUPAC name of N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide (CID 107374016) is N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide.
What is the SMILES notation for N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide?
The canonical SMILES for N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide is CNc1cnc(C(=O)Nc2cc(OC)ccc2OC)cn1.
What is the InChIKey of N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide?
The InChIKey is JFEWNMRLAZVXAA-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H16N4O3/c1-15-13-8-16-11(7-17-13)14(19)18-10-6-9(20-2)4-5-12(10)21-3/h4-8H,1-3H3,(H,15,17)(H,18,19).
What are the key properties of N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide?
N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide has a molecular weight of 288.31 g/mol, XLogP of 1.79, 5 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2,5-dimethoxyphenyl)-5-(methylamino)pyrazine-2-carboxamide is sourced from PubChem (CID 107374016), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).