N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide

C14H12F2N4O — CID 109271723

IUPACN-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide
SMILESO=C(NC1CC1)c1cnc(Nc2ccc(F)cc2F)cn1
InChIInChI=1S/C14H12F2N4O/c15-8-1-4-11(10(16)5-8)20-13-7-17-12(6-18-13)14(21)19-9-2-3-9/h1,4-7,9H,2-3H2,(H,18,20)(H,19,21)
InChIKeyZCKCKWLNLWUOFH-UHFFFAOYSA-N
MW290.27 g/mol
LogP2.39
Rot. Bonds4

About N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide

N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide (PubChem CID 109271723) has the molecular formula C14H12F2N4O and a molecular weight of 290.27 g/mol. Its IUPAC name is N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide.

Molecular Properties

Compound NameN-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide
PubChem CID109271723
Molecular FormulaC14H12F2N4O
Molecular Weight290.27 g/mol
Exact Mass290.10
IUPAC NameN-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide
SMILESO=C(NC1CC1)c1cnc(Nc2ccc(F)cc2F)cn1
InChIInChI=1S/C14H12F2N4O/c15-8-1-4-11(10(16)5-8)20-13-7-17-12(6-18-13)14(21)19-9-2-3-9/h1,4-7,9H,2-3H2,(H,18,20)(H,19,21)
InChIKeyZCKCKWLNLWUOFH-UHFFFAOYSA-N
XLogP2.39
TPSA66.91 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500290.27
LogP ≤ 52.39
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

N-cyclohexyl-5-(2-fluoroanilino)pyrazine-2-carboxamide
CID 109274738
5-(2,4-difluoroanilino)-N-pentylpyrazine-2-carboxamide
CID 109288090
N-cycloheptyl-6-(2,4-difluoroanilino)pyridazine-3-carboxamide
CID 109125066
N-cyclohexyl-6-(2,4-difluoroanilino)pyridazine-3-carboxamide
CID 109113119
5-(5-chloro-2-methylanilino)-N-cyclopropylpyrazine-2-carboxamide
CID 109271670
5-(3-chloro-4-fluoroanilino)-N-cyclopropylpyrazine-2-carboxamide
CID 109271673
N-(2,5-dichlorophenyl)-5-(2,4-difluoroanilino)pyrazine-2-carboxamide
CID 109294510
5-(2,4-difluoroanilino)-N-[2-(2-fluorophenyl)ethyl]pyrazine-2-carboxamide
CID 109284313
5-(2,4-difluoroanilino)-N-[3-(dimethylamino)propyl]pyrazine-2-carboxamide
CID 109277881
N-benzyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide
CID 109279773
5-(2,4-difluoroanilino)-N-(2,4,6-trimethylphenyl)pyrazine-2-carboxamide
CID 109292112
5-(2-bromoanilino)-N-cyclopropylpyrazine-2-carboxamide
CID 109271713

Frequently Asked Questions

What is the IUPAC name of N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide?
The IUPAC name of N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide (CID 109271723) is N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide.
What is the SMILES notation for N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide?
The canonical SMILES for N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide is O=C(NC1CC1)c1cnc(Nc2ccc(F)cc2F)cn1.
What is the InChIKey of N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide?
The InChIKey is ZCKCKWLNLWUOFH-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H12F2N4O/c15-8-1-4-11(10(16)5-8)20-13-7-17-12(6-18-13)14(21)19-9-2-3-9/h1,4-7,9H,2-3H2,(H,18,20)(H,19,21).
What are the key properties of N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide?
N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide has a molecular weight of 290.27 g/mol, XLogP of 2.39, 4 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-cyclopropyl-5-(2,4-difluoroanilino)pyrazine-2-carboxamide is sourced from PubChem (CID 109271723), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).