N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide

C21H17N5O2 — CID 109293403

IUPACN-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide
SMILESCOc1ccccc1NC(=O)c1cnc(Nc2cccc3cccnc23)cn1
InChIInChI=1S/C21H17N5O2/c1-28-18-10-3-2-8-15(18)26-21(27)17-12-24-19(13-23-17)25-16-9-4-6-14-7-5-11-22-20(14)16/h2-13H,1H3,(H,24,25)(H,26,27)
InChIKeyPZBWKJQOQCINOW-UHFFFAOYSA-N
MW371.40 g/mol
LogP4.03
Rot. Bonds5

About N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide

N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide (PubChem CID 109293403) has the molecular formula C21H17N5O2 and a molecular weight of 371.40 g/mol. Its IUPAC name is N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide.

Molecular Properties

Compound NameN-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide
PubChem CID109293403
Molecular FormulaC21H17N5O2
Molecular Weight371.40 g/mol
Exact Mass371.14
IUPAC NameN-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide
SMILESCOc1ccccc1NC(=O)c1cnc(Nc2cccc3cccnc23)cn1
InChIInChI=1S/C21H17N5O2/c1-28-18-10-3-2-8-15(18)26-21(27)17-12-24-19(13-23-17)25-16-9-4-6-14-7-5-11-22-20(14)16/h2-13H,1H3,(H,24,25)(H,26,27)
InChIKeyPZBWKJQOQCINOW-UHFFFAOYSA-N
XLogP4.03
TPSA89.03 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500371.40
LogP ≤ 54.03
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

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Related Compounds

5-(2-methoxyanilino)-N-quinolin-8-ylpyridine-2-carboxamide
CID 109199751
5-(2-ethylanilino)-N-quinolin-8-ylpyrazine-2-carboxamide
CID 109291574
5-(2,3-dimethylanilino)-N-(2-methoxyphenyl)pyrazine-2-carboxamide
CID 109291424
N-propan-2-yl-5-(quinolin-8-ylamino)pyrazine-2-carboxamide
CID 109271325
N-(2-methoxyphenyl)-2-(quinolin-8-ylamino)pyrimidine-5-carboxamide
CID 109269429
5-(2-methoxy-5-methylanilino)-N-(2-methoxyphenyl)pyrazine-2-carboxamide
CID 109293379
5-(2,6-dimethylanilino)-N-quinolin-8-ylpyrazine-2-carboxamide
CID 109291330
3-N-(2-methoxyphenyl)-5-N-quinolin-8-ylpyridine-3,5-dicarboxamide
CID 109108883
N-(1-phenylethyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide
CID 109280869
5-(4-chloro-2-methoxy-5-methylanilino)-N-(2-methoxyphenyl)pyrazine-2-carboxamide
CID 109293413
5-(5-chloro-2-methylanilino)-N-(2-methoxyphenyl)pyrazine-2-carboxamide
CID 109293027
5-(tert-butylamino)-N-(2-methoxyphenyl)pyrazine-2-carboxamide
CID 109287391

Frequently Asked Questions

What is the IUPAC name of N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide?
The IUPAC name of N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide (CID 109293403) is N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide.
What is the SMILES notation for N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide?
The canonical SMILES for N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide is COc1ccccc1NC(=O)c1cnc(Nc2cccc3cccnc23)cn1.
What is the InChIKey of N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide?
The InChIKey is PZBWKJQOQCINOW-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H17N5O2/c1-28-18-10-3-2-8-15(18)26-21(27)17-12-24-19(13-23-17)25-16-9-4-6-14-7-5-11-22-20(14)16/h2-13H,1H3,(H,24,25)(H,26,27).
What are the key properties of N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide?
N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide has a molecular weight of 371.40 g/mol, XLogP of 4.03, 5 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2-methoxyphenyl)-5-(quinolin-8-ylamino)pyrazine-2-carboxamide is sourced from PubChem (CID 109293403), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).