4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide

C19H18F2N4O2 — CID 11451572

IUPAC4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide
SMILESO=C(Nc1n[nH]c2ccccc12)N1CCC(O)(c2cc(F)cc(F)c2)CC1
InChIInChI=1S/C19H18F2N4O2/c20-13-9-12(10-14(21)11-13)19(27)5-7-25(8-6-19)18(26)22-17-15-3-1-2-4-16(15)23-24-17/h1-4,9-11,27H,5-8H2,(H2,22,23,24,26)
InChIKeyYBGOWCYUDARZNY-UHFFFAOYSA-N
MW372.38 g/mol
LogP3.36
Rot. Bonds2

About 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide

4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide (PubChem CID 11451572) has the molecular formula C19H18F2N4O2 and a molecular weight of 372.38 g/mol. Its IUPAC name is 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide.

Molecular Properties

Compound Name4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide
PubChem CID11451572
Molecular FormulaC19H18F2N4O2
Molecular Weight372.38 g/mol
Exact Mass372.14
IUPAC Name4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide
SMILESO=C(Nc1n[nH]c2ccccc12)N1CCC(O)(c2cc(F)cc(F)c2)CC1
InChIInChI=1S/C19H18F2N4O2/c20-13-9-12(10-14(21)11-13)19(27)5-7-25(8-6-19)18(26)22-17-15-3-1-2-4-16(15)23-24-17/h1-4,9-11,27H,5-8H2,(H2,22,23,24,26)
InChIKeyYBGOWCYUDARZNY-UHFFFAOYSA-N
XLogP3.36
TPSA81.25 Ų
H-Bond Donors3
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500372.38
LogP ≤ 53.36
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 103

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Related Compounds

1-[(1S)-1-(4-fluorophenyl)-2-hydroxy-2-methylpropyl]-3-[3-(4-fluorophenyl)-4-(hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]urea
CID 118184011
1-[3-(4-fluorophenyl)-4-(hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-3-[(1S)-2-hydroxy-2-methyl-1-phenylpropyl]urea
CID 118184013
1-cyclopropyl-3-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]urea
CID 137661314
1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-[2-fluoro-5-(hydroxymethyl)phenyl]urea
CID 49830670
Piperidine-1-carboxylic acid (6,7-difluoro-5-phenyl-1H-indazol-3-yl)amide
CID 9841627
4-cyano-4-(3,5-difluorophenyl)-N-(1H-indazol-3-yl)piperidine-1-carboxamide
CID 11153237
4-[3,5-bis(trifluoromethyl)phenyl]-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide
CID 11155677
4-hydroxy-N-(1H-indazol-3-yl)-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
CID 11177159
4-(5-bromo-3-chloro-2-fluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide
CID 11178839
4-[2-chloro-5-(trifluoromethyl)phenyl]-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide
CID 11201470
4-(2,4-difluorophenyl)-N-(1H-indazol-3-yl)piperazine-1-carboxamide
CID 11222041
4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxy-1-piperidinecarboxylic acid (1H-indazol-3-yl)amide
CID 11224422

Frequently Asked Questions

What is the IUPAC name of 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide?
The IUPAC name of 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide (CID 11451572) is 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide.
What is the SMILES notation for 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide?
The canonical SMILES for 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide is O=C(Nc1n[nH]c2ccccc12)N1CCC(O)(c2cc(F)cc(F)c2)CC1.
What is the InChIKey of 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide?
The InChIKey is YBGOWCYUDARZNY-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H18F2N4O2/c20-13-9-12(10-14(21)11-13)19(27)5-7-25(8-6-19)18(26)22-17-15-3-1-2-4-16(15)23-24-17/h1-4,9-11,27H,5-8H2,(H2,22,23,24,26).
What are the key properties of 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide?
4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide has a molecular weight of 372.38 g/mol, XLogP of 3.36, 2 rotatable bonds, 3 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(3,5-difluorophenyl)-4-hydroxy-N-(1H-indazol-3-yl)piperidine-1-carboxamide is sourced from PubChem (CID 11451572), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).