8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

C23H23F2N5O4 — CID 118321213

About 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 118321213) has the molecular formula C23H23F2N5O4 and a molecular weight of 471.46 g/mol. Its IUPAC name is 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
• PubChem CID: 118321213
• Molecular Formula: C23H23F2N5O4
• Molecular Weight: 471.46 g/mol
• Exact Mass: 471.17
• IUPAC Name: 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
• SMILES: Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(CO)(CO)c1cnn(C)c1
• InChI: InChI=1S/C23H23F2N5O4/c1-14-20(22(33)28-23(12-31,13-32)15-9-26-29(2)10-15)30-8-4-7-19(21(30)27-14)34-11-16-17(24)5-3-6-18(16)25/h3-10,31-32H,11-13H2,1-2H3,(H,28,33)
• InChIKey: ZEZGBSHOZARYGU-UHFFFAOYSA-N
• XLogP: 1.84
• TPSA: 113.91 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 8
• Rotatable Bonds: 8
• Heavy Atoms: 34
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	471.46
LogP ≤ 5	1.84
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	8

Frequently Asked Questions

What is the IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CID 118321213) is 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

What is the SMILES notation for 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The canonical SMILES for 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(CO)(CO)c1cnn(C)c1.

What is the InChIKey of 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The InChIKey is ZEZGBSHOZARYGU-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H23F2N5O4/c1-14-20(22(33)28-23(12-31,13-32)15-9-26-29(2)10-15)30-8-4-7-19(21(30)27-14)34-11-16-17(24)5-3-6-18(16)25/h3-10,31-32H,11-13H2,1-2H3,(H,28,33).

What are the key properties of 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 471.46 g/mol, XLogP of 1.84, 8 rotatable bonds, 3 hydrogen bond donors, and 8 hydrogen bond acceptors.

Where does this data come from?

All data for 8-[(2,6-difluorophenyl)methoxy]-N-[1,3-dihydroxy-2-(1-methylpyrazol-4-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 118321213), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).