5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide

C17H16F2N6O2 — CID 118357054

IUPAC5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide
SMILESO=C(Nc1cn2cc(-c3ccnn3C(=O)NCC(F)F)ccc2n1)C1CC1
InChIInChI=1S/C17H16F2N6O2/c18-13(19)7-20-17(27)25-12(5-6-21-25)11-3-4-15-22-14(9-24(15)8-11)23-16(26)10-1-2-10/h3-6,8-10,13H,1-2,7H2,(H,20,27)(H,23,26)
InChIKeyIOIMGNAFMPYYMH-UHFFFAOYSA-N
MW374.35 g/mol
LogP2.37
Rot. Bonds5

About 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide

5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide (PubChem CID 118357054) has the molecular formula C17H16F2N6O2 and a molecular weight of 374.35 g/mol. Its IUPAC name is 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide.

Molecular Properties

Compound Name5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide
PubChem CID118357054
Molecular FormulaC17H16F2N6O2
Molecular Weight374.35 g/mol
Exact Mass374.13
IUPAC Name5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide
SMILESO=C(Nc1cn2cc(-c3ccnn3C(=O)NCC(F)F)ccc2n1)C1CC1
InChIInChI=1S/C17H16F2N6O2/c18-13(19)7-20-17(27)25-12(5-6-21-25)11-3-4-15-22-14(9-24(15)8-11)23-16(26)10-1-2-10/h3-6,8-10,13H,1-2,7H2,(H,20,27)(H,23,26)
InChIKeyIOIMGNAFMPYYMH-UHFFFAOYSA-N
XLogP2.37
TPSA93.32 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds5
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500374.35
LogP ≤ 52.37
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

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Related Compounds

N-(6-hydroxyimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide
CID 58158532
N-[6-(3-fluoro-2-methylphenyl)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686082
N-[6-(6-amino-3-pyridinyl)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 155082189
N-[6-[3-fluoro-2-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686210
N-[6-(3,4-difluoro-2-methylphenyl)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 155081984
N-[6-[2-fluoro-6-(hydroxymethyl)-4-methylphenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686347
N-[6-[3-chloro-6-fluoro-2-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686220
N-[6-[5-[hydroxy(methoxy)methyl]-2-methylphenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686025
(3S)-3-[[6-(5-methyl-1,2,4-oxadiazol-3-yl)imidazo[1,2-a]pyridin-2-yl]carbamoyl]pyrrolidine-1-carboxylic acid
CID 118980831
4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide
CID 118363450
N-[6-[5-(methylamino)-1H-indazol-4-yl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 164718424
N-[6-(5-cyclopropyl-1H-indazol-4-yl)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 163221292

Frequently Asked Questions

What is the IUPAC name of 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide?
The IUPAC name of 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide (CID 118357054) is 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide.
What is the SMILES notation for 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide?
The canonical SMILES for 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide is O=C(Nc1cn2cc(-c3ccnn3C(=O)NCC(F)F)ccc2n1)C1CC1.
What is the InChIKey of 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide?
The InChIKey is IOIMGNAFMPYYMH-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H16F2N6O2/c18-13(19)7-20-17(27)25-12(5-6-21-25)11-3-4-15-22-14(9-24(15)8-11)23-16(26)10-1-2-10/h3-6,8-10,13H,1-2,7H2,(H,20,27)(H,23,26).
What are the key properties of 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide?
5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide has a molecular weight of 374.35 g/mol, XLogP of 2.37, 5 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide is sourced from PubChem (CID 118357054), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).