4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide

C19H19N5O3S — CID 118363450

IUPAC4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide
SMILESO=C(N[C@H]1CCOC1)c1nc(-c2ccc3nc(NC(=O)C4CC4)cn3c2)cs1
InChIInChI=1S/C19H19N5O3S/c25-17(11-1-2-11)23-15-8-24-7-12(3-4-16(24)22-15)14-10-28-19(21-14)18(26)20-13-5-6-27-9-13/h3-4,7-8,10-11,13H,1-2,5-6,9H2,(H,20,26)(H,23,25)/t13-/m0/s1
InChIKeyQAHQNCDARPTPSP-ZDUSSCGKSA-N
MW397.46 g/mol
LogP2.33
Rot. Bonds5

About 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide

4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide (PubChem CID 118363450) has the molecular formula C19H19N5O3S and a molecular weight of 397.46 g/mol. Its IUPAC name is 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide.

Molecular Properties

Compound Name4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide
PubChem CID118363450
Molecular FormulaC19H19N5O3S
Molecular Weight397.46 g/mol
Exact Mass397.12
IUPAC Name4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide
SMILESO=C(N[C@H]1CCOC1)c1nc(-c2ccc3nc(NC(=O)C4CC4)cn3c2)cs1
InChIInChI=1S/C19H19N5O3S/c25-17(11-1-2-11)23-15-8-24-7-12(3-4-16(24)22-15)14-10-28-19(21-14)18(26)20-13-5-6-27-9-13/h3-4,7-8,10-11,13H,1-2,5-6,9H2,(H,20,26)(H,23,25)/t13-/m0/s1
InChIKeyQAHQNCDARPTPSP-ZDUSSCGKSA-N
XLogP2.33
TPSA97.62 Ų
H-Bond Donors2
H-Bond Acceptors7
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500397.46
LogP ≤ 52.33
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 107

Analyze 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyrazin-6-yl]-N-(oxan-3-yl)-1,3-thiazole-2-carboxamide
CID 118357079
N-[(1R,6R)-6-amino-2,2-difluorocyclohexyl]-4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-1,3-thiazole-2-carboxamide
CID 126700888
N-(6-hydroxyimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide
CID 58158532
N-[6-(6-amino-3-pyridinyl)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 155082189
N-[6-(3,4-difluoro-2-methylphenyl)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 155081984
N-[6-(3-fluoro-2-methylphenyl)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686082
N-[6-[5-[hydroxy(methoxy)methyl]-2-methylphenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686025
N-[6-[3-fluoro-2-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686210
N-[6-[2-fluoro-6-(hydroxymethyl)-4-methylphenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686347
5-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-(2,2-difluoroethyl)pyrazole-1-carboxamide
CID 118357054
N-[6-[3-chloro-6-fluoro-2-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide
CID 154686220
(3S)-1-cyano-N-[6-(1,3-oxazol-5-yl)imidazo[1,2-a]pyridin-2-yl]pyrrolidine-3-carboxamide
CID 118981293

Frequently Asked Questions

What is the IUPAC name of 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide?
The IUPAC name of 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide (CID 118363450) is 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide.
What is the SMILES notation for 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide?
The canonical SMILES for 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide is O=C(N[C@H]1CCOC1)c1nc(-c2ccc3nc(NC(=O)C4CC4)cn3c2)cs1.
What is the InChIKey of 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide?
The InChIKey is QAHQNCDARPTPSP-ZDUSSCGKSA-N. The full InChI is InChI=1S/C19H19N5O3S/c25-17(11-1-2-11)23-15-8-24-7-12(3-4-16(24)22-15)14-10-28-19(21-14)18(26)20-13-5-6-27-9-13/h3-4,7-8,10-11,13H,1-2,5-6,9H2,(H,20,26)(H,23,25)/t13-/m0/s1.
What are the key properties of 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide?
4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide has a molecular weight of 397.46 g/mol, XLogP of 2.33, 5 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[2-(cyclopropanecarbonylamino)imidazo[1,2-a]pyridin-6-yl]-N-[(3S)-oxolan-3-yl]-1,3-thiazole-2-carboxamide is sourced from PubChem (CID 118363450), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).