(5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide

C19H15F2N3O2S — CID 118559955

IUPAC(5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide
SMILESCc1c(F)cccc1[C@@]1(C(=O)NO)Cc2nc(-c3ccc(F)cn3)sc2C1
InChIInChI=1S/C19H15F2N3O2S/c1-10-12(3-2-4-13(10)21)19(18(25)24-26)7-15-16(8-19)27-17(23-15)14-6-5-11(20)9-22-14/h2-6,9,26H,7-8H2,1H3,(H,24,25)/t19-/m1/s1
InChIKeyDTQZSNICTXHRFE-LJQANCHMSA-N
MW387.41 g/mol
LogP3.33
Rot. Bonds3

About (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide

(5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide (PubChem CID 118559955) has the molecular formula C19H15F2N3O2S and a molecular weight of 387.41 g/mol. Its IUPAC name is (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide.

Molecular Properties

Compound Name(5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide
PubChem CID118559955
Molecular FormulaC19H15F2N3O2S
Molecular Weight387.41 g/mol
Exact Mass387.09
IUPAC Name(5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide
SMILESCc1c(F)cccc1[C@@]1(C(=O)NO)Cc2nc(-c3ccc(F)cn3)sc2C1
InChIInChI=1S/C19H15F2N3O2S/c1-10-12(3-2-4-13(10)21)19(18(25)24-26)7-15-16(8-19)27-17(23-15)14-6-5-11(20)9-22-14/h2-6,9,26H,7-8H2,1H3,(H,24,25)/t19-/m1/s1
InChIKeyDTQZSNICTXHRFE-LJQANCHMSA-N
XLogP3.33
TPSA75.11 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500387.41
LogP ≤ 53.33
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

(S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(1-methyl-1H-pyrazol-5-yl)-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 118559829
(R)-5-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 118559831
(R)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(1-methyl-1H-pyrazol-5-yl)-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 118559854
(S)-5-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 118559873
(S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o-tolyl)-5,6-dihydro-4H-cyclopenta[d]thiazole-6-carboxamide
CID 118559922
(R)-2-(1,3-Dimethyl-1H-pyrazol-5-yl)-5-(3-fluoro-2-methylphenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 118559929
(S)-6-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-6-carboxamide
CID 118559948
E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(2-fluorophenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 118569928
E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(3-fluorophenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 129012802
E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(4-fluoro-2-methylphenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 129012803
E1-(abs)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)-5-(3-fluoro-2-methylphenyl)-N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5-carboxamide
CID 129012804
(1S,2R,3S)-1-fluoro-2-[2-(4-fluorophenyl)-1,3-thiazol-5-yl]-N-hydroxy-3-(2-methyl-3-pyridinyl)cyclopropane-1-carboxamide
CID 72950689

Frequently Asked Questions

What is the IUPAC name of (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide?
The IUPAC name of (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide (CID 118559955) is (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide.
What is the SMILES notation for (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide?
The canonical SMILES for (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide is Cc1c(F)cccc1[C@@]1(C(=O)NO)Cc2nc(-c3ccc(F)cn3)sc2C1.
What is the InChIKey of (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide?
The InChIKey is DTQZSNICTXHRFE-LJQANCHMSA-N. The full InChI is InChI=1S/C19H15F2N3O2S/c1-10-12(3-2-4-13(10)21)19(18(25)24-26)7-15-16(8-19)27-17(23-15)14-6-5-11(20)9-22-14/h2-6,9,26H,7-8H2,1H3,(H,24,25)/t19-/m1/s1.
What are the key properties of (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide?
(5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide has a molecular weight of 387.41 g/mol, XLogP of 3.33, 3 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for (5R)-5-(3-fluoro-2-methylphenyl)-2-(5-fluoro-2-pyridinyl)-N-hydroxy-4,6-dihydrocyclopenta[d][1,3]thiazole-5-carboxamide is sourced from PubChem (CID 118559955), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).