8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one

C23H23N5O — CID 123373856

IUPAC8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one
SMILESCCn1c(=O)c(-c2ccc(-c3cccc(C)n3)cc2C)cc2cnc(NC)nc21
InChIInChI=1S/C23H23N5O/c1-5-28-21-17(13-25-23(24-4)27-21)12-19(22(28)29)18-10-9-16(11-14(18)2)20-8-6-7-15(3)26-20/h6-13H,5H2,1-4H3,(H,24,25,27)
InChIKeyZDRKHTUKDMWQEW-UHFFFAOYSA-N
MW385.47 g/mol
LogP4.20
Rot. Bonds4

About 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one

8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one (PubChem CID 123373856) has the molecular formula C23H23N5O and a molecular weight of 385.47 g/mol. Its IUPAC name is 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

Compound Name8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one
PubChem CID123373856
Molecular FormulaC23H23N5O
Molecular Weight385.47 g/mol
Exact Mass385.19
IUPAC Name8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one
SMILESCCn1c(=O)c(-c2ccc(-c3cccc(C)n3)cc2C)cc2cnc(NC)nc21
InChIInChI=1S/C23H23N5O/c1-5-28-21-17(13-25-23(24-4)27-21)12-19(22(28)29)18-10-9-16(11-14(18)2)20-8-6-7-15(3)26-20/h6-13H,5H2,1-4H3,(H,24,25,27)
InChIKeyZDRKHTUKDMWQEW-UHFFFAOYSA-N
XLogP4.20
TPSA72.70 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds4
Heavy Atoms29
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500385.47
LogP ≤ 54.20
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

Analyze 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one with MolForge

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Related Compounds

8-[2-(2-aminoethoxy)ethyl]-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one
CID 90467492
8-(4-aminobutyl)-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
CID 166451136
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
CID 91664373
2-chloro-8-ethyl-6-[2-methyl-4-(3-methylpyrazin-2-yl)phenyl]pyrido[2,3-d]pyrimidin-7-one
CID 86683497
8-ethyl-6-(2-methylphenyl)-2-methylsulfanylpyrido[2,3-d]pyrimidin-7-one
CID 102178580
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-(3,4-dihydroxybutyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
CID 90467066
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[(3-methyloxetan-3-yl)amino]pyrido[2,3-d]pyrimidin-7-one
CID 123751190
2-anilino-6-(3,5-dimethylphenyl)-8-ethylpyrido[2,3-d]pyrimidin-7-one
CID 11537968
8-(4-aminobutyl)-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-[3-(2-oxopyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one
CID 169408424
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-iodopiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one
CID 166170812
6-(2-chloro-4-pyridin-2-ylphenyl)-8-ethyl-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]pyrido[2,3-d]pyrimidin-7-one
CID 70934558
6-[2-chloro-4-(6-methyl-3-pyridinyl)phenyl]-8-ethyl-2-[4-(1-propan-2-ylpiperidin-4-yl)anilino]pyrido[2,3-d]pyrimidin-7-one
CID 89473909

Frequently Asked Questions

What is the IUPAC name of 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?
The IUPAC name of 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one (CID 123373856) is 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one.
What is the SMILES notation for 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?
The canonical SMILES for 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one is CCn1c(=O)c(-c2ccc(-c3cccc(C)n3)cc2C)cc2cnc(NC)nc21.
What is the InChIKey of 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?
The InChIKey is ZDRKHTUKDMWQEW-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H23N5O/c1-5-28-21-17(13-25-23(24-4)27-21)12-19(22(28)29)18-10-9-16(11-14(18)2)20-8-6-7-15(3)26-20/h6-13H,5H2,1-4H3,(H,24,25,27).
What are the key properties of 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?
8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 385.47 g/mol, XLogP of 4.20, 4 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 8-ethyl-2-(methylamino)-6-[2-methyl-4-(6-methyl-2-pyridinyl)phenyl]pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 123373856), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).