N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide

C21H25N5O — CID 124910480

IUPACN-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide
SMILESC[C@@H]1c2nc(CC(=O)NC3CC3)cn2CCN1Cc1cccc2[nH]ccc12
InChIInChI=1S/C21H25N5O/c1-14-21-24-17(11-20(27)23-16-5-6-16)13-26(21)10-9-25(14)12-15-3-2-4-19-18(15)7-8-22-19/h2-4,7-8,13-14,16,22H,5-6,9-12H2,1H3,(H,23,27)/t14-/m1/s1
InChIKeyQWZJGVWPNBJYHQ-CQSZACIVSA-N
MW363.47 g/mol
LogP2.76
Rot. Bonds5

About N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide

N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide (PubChem CID 124910480) has the molecular formula C21H25N5O and a molecular weight of 363.47 g/mol. Its IUPAC name is N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide.

Molecular Properties

Compound NameN-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide
PubChem CID124910480
Molecular FormulaC21H25N5O
Molecular Weight363.47 g/mol
Exact Mass363.21
IUPAC NameN-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide
SMILESC[C@@H]1c2nc(CC(=O)NC3CC3)cn2CCN1Cc1cccc2[nH]ccc12
InChIInChI=1S/C21H25N5O/c1-14-21-24-17(11-20(27)23-16-5-6-16)13-26(21)10-9-25(14)12-15-3-2-4-19-18(15)7-8-22-19/h2-4,7-8,13-14,16,22H,5-6,9-12H2,1H3,(H,23,27)/t14-/m1/s1
InChIKeyQWZJGVWPNBJYHQ-CQSZACIVSA-N
XLogP2.76
TPSA65.95 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds5
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500363.47
LogP ≤ 52.76
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide with MolForge

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Related Compounds

2-(7-cyclopentyl-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl)-N-cyclopropylacetamide
CID 131658212
2-[(8R)-7-cyclopentyl-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-cyclopropylacetamide
CID 124910267
N-cyclopropyl-2-(1H-indol-4-ylmethylamino)acetamide
CID 63000574
N-(cyclopropylmethyl)-2-[7-(1H-indole-3-carbonyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide
CID 131694015
(7R)-N-cyclopropyl-5-(1H-indol-4-ylmethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-7-carboxamide
CID 124786935
2-(1H-indol-4-yl)-N-(1-methylpiperidin-3-yl)acetamide
CID 100959575
N-[[6-[(2S)-1-(1H-indol-4-ylmethyl)pyrrolidin-2-yl]-2-pyridinyl]methyl]acetamide
CID 125019695
2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide
CID 124910184
2-[(8R)-7-(furan-3-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(2-methoxyethyl)acetamide
CID 124790256
N-[[2-[(2S)-1-(1H-indol-4-ylmethyl)pyrrolidin-2-yl]pyrimidin-4-yl]methyl]acetamide
CID 124946512
2-[7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-[(5-methylpyrazin-2-yl)methyl]acetamide
CID 133143017
6-[(2S)-1-(1H-indol-4-ylmethyl)pyrrolidin-2-yl]-N-methylpyrazin-2-amine
CID 124996383

Frequently Asked Questions

What is the IUPAC name of N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide?
The IUPAC name of N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide (CID 124910480) is N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide.
What is the SMILES notation for N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide?
The canonical SMILES for N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide is C[C@@H]1c2nc(CC(=O)NC3CC3)cn2CCN1Cc1cccc2[nH]ccc12.
What is the InChIKey of N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide?
The InChIKey is QWZJGVWPNBJYHQ-CQSZACIVSA-N. The full InChI is InChI=1S/C21H25N5O/c1-14-21-24-17(11-20(27)23-16-5-6-16)13-26(21)10-9-25(14)12-15-3-2-4-19-18(15)7-8-22-19/h2-4,7-8,13-14,16,22H,5-6,9-12H2,1H3,(H,23,27)/t14-/m1/s1.
What are the key properties of N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide?
N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide has a molecular weight of 363.47 g/mol, XLogP of 2.76, 5 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-cyclopropyl-2-[(8R)-7-(1H-indol-4-ylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide is sourced from PubChem (CID 124910480), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).