6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine

C6H4ClF3N2 — CID 130102435

IUPAC6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine
SMILESNc1cc(C(F)F)c(F)c(Cl)n1
InChIInChI=1S/C6H4ClF3N2/c7-5-4(8)2(6(9)10)1-3(11)12-5/h1,6H,(H2,11,12)
InChIKeySZQHRJKTLONROO-UHFFFAOYSA-N
MW196.56 g/mol
LogP2.39
Rot. Bonds1

About 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine

6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine (PubChem CID 130102435) has the molecular formula C6H4ClF3N2 and a molecular weight of 196.56 g/mol. Its IUPAC name is 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine.

Molecular Properties

Compound Name6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine
PubChem CID130102435
Molecular FormulaC6H4ClF3N2
Molecular Weight196.56 g/mol
Exact Mass196.00
IUPAC Name6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine
SMILESNc1cc(C(F)F)c(F)c(Cl)n1
InChIInChI=1S/C6H4ClF3N2/c7-5-4(8)2(6(9)10)1-3(11)12-5/h1,6H,(H2,11,12)
InChIKeySZQHRJKTLONROO-UHFFFAOYSA-N
XLogP2.39
TPSA38.91 Ų
H-Bond Donors1
H-Bond Acceptors2
Rotatable Bonds1
Heavy Atoms12
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500196.56
LogP ≤ 52.39
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 102

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

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Related Compounds

6-(chloromethyl)-4-(difluoromethyl)-5-fluoropyridin-2-amine
CID 130104065
6-amino-2-chloro-4-(difluoromethyl)pyridine-3-sulfonamide
CID 130103106
4-(difluoromethyl)-5-fluoro-6-nitropyridin-2-amine
CID 130103945
6-chloro-5-(difluoromethyl)-2-fluoropyridin-3-amine
CID 130102456
6-amino-3-chloro-4-(difluoromethyl)pyridine-2-carboxylic acid
CID 130102887
6-amino-3-chloro-4-(difluoromethyl)pyridine-2-carboxamide
CID 130103139
6-bromo-5-(chloromethyl)-4-(difluoromethyl)pyridin-2-amine
CID 130101938
6-chloro-4-(difluoromethyl)-2-fluoropyridin-3-amine
CID 130102458
methyl 2-[6-amino-4-(difluoromethyl)-3-fluoro-2-pyridinyl]acetate
CID 134675998
6-chloro-5-(difluoromethyl)-4-methoxypyridin-2-amine
CID 130102534
6-(chloromethyl)-4-(difluoromethyl)-5-iodopyridin-2-amine
CID 130105343
6-(aminomethyl)-4-(difluoromethyl)pyridine-2,5-diamine
CID 118836943

Frequently Asked Questions

What is the IUPAC name of 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine?
The IUPAC name of 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine (CID 130102435) is 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine.
What is the SMILES notation for 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine?
The canonical SMILES for 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine is Nc1cc(C(F)F)c(F)c(Cl)n1.
What is the InChIKey of 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine?
The InChIKey is SZQHRJKTLONROO-UHFFFAOYSA-N. The full InChI is InChI=1S/C6H4ClF3N2/c7-5-4(8)2(6(9)10)1-3(11)12-5/h1,6H,(H2,11,12).
What are the key properties of 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine?
6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine has a molecular weight of 196.56 g/mol, XLogP of 2.39, 1 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 6-chloro-4-(difluoromethyl)-5-fluoropyridin-2-amine is sourced from PubChem (CID 130102435), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).