5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine

C8H10F2N4 — CID 130607022

IUPAC5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine
SMILESNc1cnc(N2CCC(F)(F)C2)cn1
InChIInChI=1S/C8H10F2N4/c9-8(10)1-2-14(5-8)7-4-12-6(11)3-13-7/h3-4H,1-2,5H2,(H2,11,12)
InChIKeyUQROECATQNPGRO-UHFFFAOYSA-N
MW200.19 g/mol
LogP0.90
Rot. Bonds1

About 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine

5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine (PubChem CID 130607022) has the molecular formula C8H10F2N4 and a molecular weight of 200.19 g/mol. Its IUPAC name is 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine.

Molecular Properties

Compound Name5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine
PubChem CID130607022
Molecular FormulaC8H10F2N4
Molecular Weight200.19 g/mol
Exact Mass200.09
IUPAC Name5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine
SMILESNc1cnc(N2CCC(F)(F)C2)cn1
InChIInChI=1S/C8H10F2N4/c9-8(10)1-2-14(5-8)7-4-12-6(11)3-13-7/h3-4H,1-2,5H2,(H2,11,12)
InChIKeyUQROECATQNPGRO-UHFFFAOYSA-N
XLogP0.90
TPSA55.04 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds1
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500200.19
LogP ≤ 50.90
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

6-(Pyrrolidin-1-yl)pyrazin-2-amine
CID 66520349
N2-cyclobutyl-N2-methylpyrazine-2,5-diamine
CID 116356878
Pyrazine, 2-(1-pyrrolidinyl)-
CID 60052430
1-{[1-(difluoromethyl)-1H-imidazol-2-yl]methyl}piperazine
CID 16227164
1-N-pyrazin-2-yl-3-N-(2,2,2-trifluoroethyl)cyclobutane-1,3-diamine
CID 136571641
N-[[(3R)-1-(2,2-difluoroethyl)pyrrolidin-3-yl]methyl]pyrazin-2-amine
CID 164629971
2-N,2-N,3-N-trimethyl-3-N-[(3S)-3-pyrrolidin-1-ylbutyl]pyrazine-2,3-diamine
CID 164631385
2-N-ethyl-3-N-methyl-3-N-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrazine-2,3-diamine
CID 164639580
2-Chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrazine
CID 86681768
2-(4,4-Difluoropiperidin-1-yl)pyrazine
CID 121199090
2-(3,3-Difluoropyrrolidin-1-yl)pyrazine
CID 122269216
Difluoro-(6-pyrrolidin-1-ylpyrazin-2-yl)borane
CID 142754024

Frequently Asked Questions

What is the IUPAC name of 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine?
The IUPAC name of 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine (CID 130607022) is 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine.
What is the SMILES notation for 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine?
The canonical SMILES for 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine is Nc1cnc(N2CCC(F)(F)C2)cn1.
What is the InChIKey of 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine?
The InChIKey is UQROECATQNPGRO-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H10F2N4/c9-8(10)1-2-14(5-8)7-4-12-6(11)3-13-7/h3-4H,1-2,5H2,(H2,11,12).
What are the key properties of 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine?
5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine has a molecular weight of 200.19 g/mol, XLogP of 0.90, 1 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(3,3-difluoropyrrolidin-1-yl)pyrazin-2-amine is sourced from PubChem (CID 130607022), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).