2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one

C22H26N4O2 — CID 135307322

IUPAC2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one
SMILESO=C1N(C2CC2)CCC12CCN(c1ncc(OCc3ccccc3)cn1)CC2
InChIInChI=1S/C22H26N4O2/c27-20-22(10-13-26(20)18-6-7-18)8-11-25(12-9-22)21-23-14-19(15-24-21)28-16-17-4-2-1-3-5-17/h1-5,14-15,18H,6-13,16H2
InChIKeyHFYXNCRSUOCOBN-UHFFFAOYSA-N
MW378.48 g/mol
LogP3.04
Rot. Bonds5

About 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one

2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one (PubChem CID 135307322) has the molecular formula C22H26N4O2 and a molecular weight of 378.48 g/mol. Its IUPAC name is 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one.

Molecular Properties

Compound Name2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one
PubChem CID135307322
Molecular FormulaC22H26N4O2
Molecular Weight378.48 g/mol
Exact Mass378.21
IUPAC Name2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one
SMILESO=C1N(C2CC2)CCC12CCN(c1ncc(OCc3ccccc3)cn1)CC2
InChIInChI=1S/C22H26N4O2/c27-20-22(10-13-26(20)18-6-7-18)8-11-25(12-9-22)21-23-14-19(15-24-21)28-16-17-4-2-1-3-5-17/h1-5,14-15,18H,6-13,16H2
InChIKeyHFYXNCRSUOCOBN-UHFFFAOYSA-N
XLogP3.04
TPSA58.56 Ų
H-Bond Donors
H-Bond Acceptors5
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500378.48
LogP ≤ 53.04
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 105

Analyze 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-(5-phenylmethoxypyrimidin-2-yl)-1,4-diazepan-6-ol
CID 146241882
tert-butyl N-[3,3-dimethyl-1-(5-phenylmethoxypyrimidin-2-yl)piperidin-4-yl]carbamate
CID 171498916
tert-butyl (2R,6S)-2,6-dimethyl-4-(5-phenylmethoxypyrimidin-2-yl)piperazine-1-carboxylate
CID 167450386
7-(5-phenylmethoxypyrimidin-2-yl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine
CID 171498943
2-(4-hydroxycyclohexyl)-9-[5-(2-oxo-1-pyridinyl)pyrimidin-2-yl]-2,9-diazaspiro[4.5]decan-1-one
CID 66722612
N-[2-(4-methylpiperidin-1-yl)pyrimidin-5-yl]-2-phenylmethoxyacetamide
CID 122299799
5-[(4-fluorophenyl)methoxy]-2-piperazin-1-ylpyrimidine
CID 157163231
3-benzyl-6-[(5-phenylmethoxy-2-pyridinyl)methyl]piperazine-2,5-dione
CID 58981828
1'-(5-ethylpyrimidin-2-yl)spiro[2,5-dihydro-1H-2-benzazepine-4,4'-piperidine]-3-one
CID 97415799
1-[(1S)-2,2-dichlorocyclopropyl]-4-phenylmethoxybenzene
CID 125154534
2-(4-phenylmethoxypiperidin-1-yl)pyrimidine
CID 95811444
5-[(4-fluorophenyl)methoxy]-2-piperazin-1-ylpyrimidine;hydrochloride
CID 172813583

Frequently Asked Questions

What is the IUPAC name of 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one?
The IUPAC name of 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one (CID 135307322) is 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one.
What is the SMILES notation for 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one?
The canonical SMILES for 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one is O=C1N(C2CC2)CCC12CCN(c1ncc(OCc3ccccc3)cn1)CC2.
What is the InChIKey of 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one?
The InChIKey is HFYXNCRSUOCOBN-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H26N4O2/c27-20-22(10-13-26(20)18-6-7-18)8-11-25(12-9-22)21-23-14-19(15-24-21)28-16-17-4-2-1-3-5-17/h1-5,14-15,18H,6-13,16H2.
What are the key properties of 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one?
2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one has a molecular weight of 378.48 g/mol, XLogP of 3.04, 5 rotatable bonds, 0 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-cyclopropyl-8-(5-phenylmethoxypyrimidin-2-yl)-2,8-diazaspiro[4.5]decan-1-one is sourced from PubChem (CID 135307322), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).