5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide

C10H12F2N2O4 — CID 136588722

IUPAC5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide
SMILESO=C(NC[C@@H](O)CO)c1ccc(OC(F)F)cn1
InChIInChI=1S/C10H12F2N2O4/c11-10(12)18-7-1-2-8(13-4-7)9(17)14-3-6(16)5-15/h1-2,4,6,10,15-16H,3,5H2,(H,14,17)/t6-/m1/s1
InChIKeyINCRFPYVPWVBFG-ZCFIWIBFSA-N
MW262.21 g/mol
LogP-0.23
Rot. Bonds6

About 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide

5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide (PubChem CID 136588722) has the molecular formula C10H12F2N2O4 and a molecular weight of 262.21 g/mol. Its IUPAC name is 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide.

Molecular Properties

Compound Name5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide
PubChem CID136588722
Molecular FormulaC10H12F2N2O4
Molecular Weight262.21 g/mol
Exact Mass262.08
IUPAC Name5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide
SMILESO=C(NC[C@@H](O)CO)c1ccc(OC(F)F)cn1
InChIInChI=1S/C10H12F2N2O4/c11-10(12)18-7-1-2-8(13-4-7)9(17)14-3-6(16)5-15/h1-2,4,6,10,15-16H,3,5H2,(H,14,17)/t6-/m1/s1
InChIKeyINCRFPYVPWVBFG-ZCFIWIBFSA-N
XLogP-0.23
TPSA91.68 Ų
H-Bond Donors3
H-Bond Acceptors5
Rotatable Bonds6
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500262.21
LogP ≤ 5-0.23
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 105

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Related Compounds

5-bromo-N-[(2S)-2,3-dihydroxypropyl]pyridine-2-carboxamide
CID 124510748
3-(difluoromethoxy)-N-(2,3-dihydroxypropyl)benzamide
CID 66175780
5-(difluoromethoxy)-N-(2-ethyltetrazol-5-yl)pyridine-2-carboxamide
CID 154783980
5-(difluoromethoxy)-N-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-ylmethyl)pyridine-2-carboxamide
CID 136570872
N-[(2R)-2,3-dihydroxypropyl]-5-[[5-(4-fluorophenyl)-1,3-oxazol-2-yl]amino]pyridine-2-carboxamide
CID 155585279
N-(2,3-dihydroxypropyl)-4-ethoxybenzamide
CID 66176423
5-bromo-N-[4-(difluoromethoxy)phenyl]pyridine-2-carboxamide
CID 62953190
5-bromo-N-(2,2-difluoroethyl)pyridine-2-carboxamide
CID 79080153
N-(2,3-dihydroxypropyl)-1-methyl-6-oxopyridazine-3-carboxamide
CID 66176866
methyl (2R)-2-[[5-(difluoromethoxy)pyridine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoate
CID 136588705
methyl 2-[(5-butan-2-yloxypyridine-2-carbonyl)amino]acetate
CID 70798097
N-hydroxy-5-propan-2-yloxypyridine-2-carboxamide
CID 58126135

Frequently Asked Questions

What is the IUPAC name of 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide?
The IUPAC name of 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide (CID 136588722) is 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide.
What is the SMILES notation for 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide?
The canonical SMILES for 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide is O=C(NC[C@@H](O)CO)c1ccc(OC(F)F)cn1.
What is the InChIKey of 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide?
The InChIKey is INCRFPYVPWVBFG-ZCFIWIBFSA-N. The full InChI is InChI=1S/C10H12F2N2O4/c11-10(12)18-7-1-2-8(13-4-7)9(17)14-3-6(16)5-15/h1-2,4,6,10,15-16H,3,5H2,(H,14,17)/t6-/m1/s1.
What are the key properties of 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide?
5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide has a molecular weight of 262.21 g/mol, XLogP of -0.23, 6 rotatable bonds, 3 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(difluoromethoxy)-N-[(2R)-2,3-dihydroxypropyl]pyridine-2-carboxamide is sourced from PubChem (CID 136588722), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).