5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one

C18H14FN5O — CID 137372612

IUPAC5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one
SMILESCc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccn23)c[nH]c1=O
InChIInChI=1S/C18H14FN5O/c1-10-8-12(9-22-18(10)25)15-14(11-2-4-13(19)5-3-11)23-16(20)17-21-6-7-24(15)17/h2-9H,1H3,(H2,20,23)(H,22,25)
InChIKeyKQBXZBNMMFUVBT-UHFFFAOYSA-N
MW335.34 g/mol
LogP2.78
Rot. Bonds2

About 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one

5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one (PubChem CID 137372612) has the molecular formula C18H14FN5O and a molecular weight of 335.34 g/mol. Its IUPAC name is 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one.

Molecular Properties

Compound Name5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one
PubChem CID137372612
Molecular FormulaC18H14FN5O
Molecular Weight335.34 g/mol
Exact Mass335.12
IUPAC Name5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one
SMILESCc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccn23)c[nH]c1=O
InChIInChI=1S/C18H14FN5O/c1-10-8-12(9-22-18(10)25)15-14(11-2-4-13(19)5-3-11)23-16(20)17-21-6-7-24(15)17/h2-9H,1H3,(H2,20,23)(H,22,25)
InChIKeyKQBXZBNMMFUVBT-UHFFFAOYSA-N
XLogP2.78
TPSA89.07 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds2
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500335.34
LogP ≤ 52.78
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

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Related Compounds

5-(2-chloro-6-methyl-4-pyridinyl)-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-8-amine
CID 137372402
6-(4-fluorophenyl)-5-(3-methylimidazo[1,2-a]pyridin-6-yl)imidazo[1,2-a]pyrazin-8-amine
CID 137372632
6-(4-fluorophenyl)-5-(2-fluoroquinolin-6-yl)imidazo[1,2-a]pyrazin-8-amine
CID 137372584
6-(4-fluorophenyl)-5-(3-methylbenzotriazol-5-yl)imidazo[1,2-a]pyrazin-8-amine
CID 137372437
6-(3-fluorophenyl)-5-[2-methyl-6-(methylamino)-4-pyridinyl]imidazo[1,2-a]pyrazin-8-amine
CID 137372409
5-[2-fluoro-6-(methylamino)-4-pyridinyl]-6-phenylimidazo[1,2-a]pyrazin-8-amine
CID 137372412
6-[8-amino-6-(3-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]naphthalen-1-ol
CID 137372580
6-[8-amino-6-(3-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-N,N-dimethylquinolin-8-amine
CID 137372474
6-(3-fluorophenyl)-5-(8-fluoroquinolin-6-yl)imidazo[1,2-a]pyrazin-8-amine
CID 137372339
5-amino-7-(4-fluorophenyl)-2-[(5-methyl-1,3-oxazol-4-yl)methyl]-8-(5-methyl-6-oxo-1H-pyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one
CID 156863703
6-(1-methylpyrazol-3-yl)-5-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-a]pyrazin-8-amine
CID 137372534
8-amino-N-(2,2-dimethylpropyl)-6-(4-fluorophenyl)-5-(4-methylquinolin-6-yl)imidazo[1,2-a]pyrazine-2-carboxamide
CID 152705743

Frequently Asked Questions

What is the IUPAC name of 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one?
The IUPAC name of 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one (CID 137372612) is 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one.
What is the SMILES notation for 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one?
The canonical SMILES for 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one is Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccn23)c[nH]c1=O.
What is the InChIKey of 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one?
The InChIKey is KQBXZBNMMFUVBT-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H14FN5O/c1-10-8-12(9-22-18(10)25)15-14(11-2-4-13(19)5-3-11)23-16(20)17-21-6-7-24(15)17/h2-9H,1H3,(H2,20,23)(H,22,25).
What are the key properties of 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one?
5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one has a molecular weight of 335.34 g/mol, XLogP of 2.78, 2 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[8-amino-6-(4-fluorophenyl)imidazo[1,2-a]pyrazin-5-yl]-3-methyl-1H-pyridin-2-one is sourced from PubChem (CID 137372612), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).