5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine

C18H15F3N4O — CID 141223183

IUPAC5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine
SMILESNc1ccc(-c2cn(C3CC3)c(-c3ccc(OC(F)(F)F)cc3)n2)cn1
InChIInChI=1S/C18H15F3N4O/c19-18(20,21)26-14-6-1-11(2-7-14)17-24-15(10-25(17)13-4-5-13)12-3-8-16(22)23-9-12/h1-3,6-10,13H,4-5H2,(H2,22,23)
InChIKeyRMATUXVWCCMENG-UHFFFAOYSA-N
MW360.34 g/mol
LogP4.43
Rot. Bonds4

About 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine

5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine (PubChem CID 141223183) has the molecular formula C18H15F3N4O and a molecular weight of 360.34 g/mol. Its IUPAC name is 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine.

Molecular Properties

Compound Name5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine
PubChem CID141223183
Molecular FormulaC18H15F3N4O
Molecular Weight360.34 g/mol
Exact Mass360.12
IUPAC Name5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine
SMILESNc1ccc(-c2cn(C3CC3)c(-c3ccc(OC(F)(F)F)cc3)n2)cn1
InChIInChI=1S/C18H15F3N4O/c19-18(20,21)26-14-6-1-11(2-7-14)17-24-15(10-25(17)13-4-5-13)12-3-8-16(22)23-9-12/h1-3,6-10,13H,4-5H2,(H2,22,23)
InChIKeyRMATUXVWCCMENG-UHFFFAOYSA-N
XLogP4.43
TPSA65.96 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds4
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500360.34
LogP ≤ 54.43
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

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Related Compounds

5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]-1H-pyridin-2-one
CID 141223187
4-cyclopropyl-3-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazole-5-thione
CID 116628946
1-[(2S)-2-[5-(6-amino-3-pyridinyl)-2-pyridinyl]pyrrolidin-1-yl]-2-(4-methoxyphenoxy)-2-methylpropan-1-one
CID 92615839
2-cyclopropyl-4-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-5-amine
CID 62076679
4-[1-(4-chlorophenyl)-4-[4-(trifluoromethoxy)phenyl]imidazol-2-yl]benzenesulfonamide
CID 22998138
ethyl 3-cyclopropyl-5-pyrimidin-5-yl-2-[4-(trifluoromethoxy)phenyl]imidazole-4-carboxylate
CID 67133071
5-(1,2-dicyclopropylimidazol-4-yl)-3-(trifluoromethyl)pyridin-2-amine
CID 134280965
2-[4-(trifluoromethoxy)phenyl]pyrimidin-4-amine
CID 62202664
1-cyclopropyl-N-[4-(trifluoromethoxy)phenyl]imidazol-2-amine
CID 106557392
2,3-dimethyl-6-[4-(trifluoromethoxy)phenyl]imidazo[1,2-a]pyrimidine
CID 142362621
5-[2-[3-(trifluoromethoxy)phenoxy]pyrimidin-5-yl]pyridin-2-amine
CID 162507379
5-[4-(trifluoromethoxy)phenyl]-2,3-bis(trifluoromethyl)pyridine
CID 118991248

Frequently Asked Questions

What is the IUPAC name of 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine?
The IUPAC name of 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine (CID 141223183) is 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine.
What is the SMILES notation for 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine?
The canonical SMILES for 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine is Nc1ccc(-c2cn(C3CC3)c(-c3ccc(OC(F)(F)F)cc3)n2)cn1.
What is the InChIKey of 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine?
The InChIKey is RMATUXVWCCMENG-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H15F3N4O/c19-18(20,21)26-14-6-1-11(2-7-14)17-24-15(10-25(17)13-4-5-13)12-3-8-16(22)23-9-12/h1-3,6-10,13H,4-5H2,(H2,22,23).
What are the key properties of 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine?
5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine has a molecular weight of 360.34 g/mol, XLogP of 4.43, 4 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[1-cyclopropyl-2-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]pyridin-2-amine is sourced from PubChem (CID 141223183), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).