6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide

C18H16F2N4O — CID 144985682

IUPAC6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide
SMILESNC(=O)c1cnc2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)cn12
InChIInChI=1S/C18H16F2N4O/c19-11-3-5-14(20)13(8-11)15-2-1-7-23(15)12-4-6-17-22-9-16(18(21)25)24(17)10-12/h3-6,8-10,15H,1-2,7H2,(H2,21,25)/t15-/m1/s1
InChIKeyHQANSIBDVQPHIT-OAHLLOKOSA-N
MW342.35 g/mol
LogP3.05
Rot. Bonds3

About 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide

6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 144985682) has the molecular formula C18H16F2N4O and a molecular weight of 342.35 g/mol. Its IUPAC name is 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

Compound Name6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide
PubChem CID144985682
Molecular FormulaC18H16F2N4O
Molecular Weight342.35 g/mol
Exact Mass342.13
IUPAC Name6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide
SMILESNC(=O)c1cnc2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)cn12
InChIInChI=1S/C18H16F2N4O/c19-11-3-5-14(20)13(8-11)15-2-1-7-23(15)12-4-6-17-22-9-16(18(21)25)24(17)10-12/h3-6,8-10,15H,1-2,7H2,(H2,21,25)/t15-/m1/s1
InChIKeyHQANSIBDVQPHIT-OAHLLOKOSA-N
XLogP3.05
TPSA63.63 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds3
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500342.35
LogP ≤ 53.05
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

Analyze 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide with MolForge

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Related Compounds

[6-[(2S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridin-3-yl]-[(3S)-3-hydroxypyrrolidin-1-yl]methanone
CID 118590398
6-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-[4-(3-hydroxypyrrolidin-1-yl)phenyl]sulfonylimidazo[1,2-a]pyridine-3-carboxamide
CID 118590455
6-[2-(2,5-difluorophenyl)piperidin-1-yl]-N-[4-[(3S)-3-hydroxypyrrolidin-1-yl]phenyl]sulfonylimidazo[1,2-a]pyridine-3-carboxamide
CID 118590304
6-[2-(2,5-difluorophenyl)piperidin-1-yl]-N-[4-(3-hydroxypyrrolidin-1-yl)phenyl]sulfonylimidazo[1,2-a]pyridine-3-carboxamide
CID 118590306
6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-[4-(1,2,4-triazol-1-yl)phenyl]sulfonylimidazo[1,2-a]pyridine-3-carboxamide
CID 118590605
N-[cyclopropylmethyl(pyridin-3-yl)sulfamoyl]-6-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide
CID 118590596
6-[2-[5-fluoro-2-[(3R)-oxolan-3-yl]oxyphenyl]pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxylic acid
CID 118590619
6-[2-(2,5-difluorophenyl)piperidin-1-yl]-N-[[6-[(3S)-3-hydroxypyrrolidin-1-yl]-3-pyridinyl]sulfonyl]imidazo[1,2-a]pyridine-3-carboxamide
CID 118590295
6-[(2R)-2-(5-fluoro-2-methoxyphenyl)pyrrolidin-1-yl]-N-[methyl(propyl)sulfamoyl]imidazo[1,2-a]pyridine-3-carboxamide
CID 118590610
1-[6-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-1-iodourea
CID 87369260
N-[6-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]acetamide
CID 67308144
6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-amine
CID 58334496

Frequently Asked Questions

What is the IUPAC name of 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide?
The IUPAC name of 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide (CID 144985682) is 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide.
What is the SMILES notation for 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide?
The canonical SMILES for 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide is NC(=O)c1cnc2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)cn12.
What is the InChIKey of 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide?
The InChIKey is HQANSIBDVQPHIT-OAHLLOKOSA-N. The full InChI is InChI=1S/C18H16F2N4O/c19-11-3-5-14(20)13(8-11)15-2-1-7-23(15)12-4-6-17-22-9-16(18(21)25)24(17)10-12/h3-6,8-10,15H,1-2,7H2,(H2,21,25)/t15-/m1/s1.
What are the key properties of 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide?
6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 342.35 g/mol, XLogP of 3.05, 3 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]imidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 144985682), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).