1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine

C15H16F3N3 — CID 153398901

IUPAC1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine
SMILESNC1CCCN(c2ccc(C(F)(F)F)c3ncccc23)C1
InChIInChI=1S/C15H16F3N3/c16-15(17,18)12-5-6-13(11-4-1-7-20-14(11)12)21-8-2-3-10(19)9-21/h1,4-7,10H,2-3,8-9,19H2
InChIKeyFYBSCGGPUCIOLW-UHFFFAOYSA-N
MW295.31 g/mol
LogP3.18
Rot. Bonds1

About 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine

1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine (PubChem CID 153398901) has the molecular formula C15H16F3N3 and a molecular weight of 295.31 g/mol. Its IUPAC name is 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine.

Molecular Properties

Compound Name1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine
PubChem CID153398901
Molecular FormulaC15H16F3N3
Molecular Weight295.31 g/mol
Exact Mass295.13
IUPAC Name1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine
SMILESNC1CCCN(c2ccc(C(F)(F)F)c3ncccc23)C1
InChIInChI=1S/C15H16F3N3/c16-15(17,18)12-5-6-13(11-4-1-7-20-14(11)12)21-8-2-3-10(19)9-21/h1,4-7,10H,2-3,8-9,19H2
InChIKeyFYBSCGGPUCIOLW-UHFFFAOYSA-N
XLogP3.18
TPSA42.15 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds1
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500295.31
LogP ≤ 53.18
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

(3R,5S)-5-methyl-1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine
CID 129240522
2,2,2-trifluoroacetate;[1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-yl]azanium
CID 153398900
4-methyl-1-[8-(trifluoromethyl)quinolin-5-yl]pyrrolidin-3-amine
CID 174114905
1-(2-methyl-3-pyridinyl)piperidin-3-amine
CID 79043598
5-methyl-1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-ol
CID 129241108
5-[3-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile
CID 164852052
1-(3-methyl-2-pyridinyl)piperidin-3-amine
CID 62253167
5-(3-methoxypiperidin-1-yl)quinolin-8-amine
CID 102955780
2-(trifluoromethyl)-4-[8-(trifluoromethyl)quinolin-4-yl]morpholine
CID 56881153
(3R)-N-(4-aminocyclohexyl)-N-methyl-1-[3-(trifluoromethyl)-2-pyridinyl]piperidine-3-carboxamide
CID 124686664
methyl (2R,6R)-6-methyl-4-[8-(trifluoromethyl)quinolin-5-yl]morpholine-2-carboxylate
CID 156648946
1-[3-(trifluoromethyl)-2-pyridinyl]piperidine-3-carboxamide
CID 47174336

Frequently Asked Questions

What is the IUPAC name of 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine?
The IUPAC name of 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine (CID 153398901) is 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine.
What is the SMILES notation for 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine?
The canonical SMILES for 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine is NC1CCCN(c2ccc(C(F)(F)F)c3ncccc23)C1.
What is the InChIKey of 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine?
The InChIKey is FYBSCGGPUCIOLW-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H16F3N3/c16-15(17,18)12-5-6-13(11-4-1-7-20-14(11)12)21-8-2-3-10(19)9-21/h1,4-7,10H,2-3,8-9,19H2.
What are the key properties of 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine?
1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine has a molecular weight of 295.31 g/mol, XLogP of 3.18, 1 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[8-(trifluoromethyl)quinolin-5-yl]piperidin-3-amine is sourced from PubChem (CID 153398901), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).