5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine

C₁₀₆H₁₀₁N₄₃OS₃ — CID 157055173

About 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine

5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine (PubChem CID 157055173) has the molecular formula C₁₀₆H₁₀₁N₄₃OS₃ and a molecular weight of 2089.47 g/mol. Its IUPAC name is 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

• Compound Name: 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
• PubChem CID: 157055173
• Molecular Formula: C₁₀₆H₁₀₁N₄₃OS₃
• Molecular Weight: 2089.47 g/mol
• Exact Mass: 2087.83
• IUPAC Name: 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
• SMILES: COc1ccccc1Nc1nccn2c(-c3cnn(C)c3)cnc12.Cc1nc(C)c(-c2cnc3c(Nc4cccc(N(C)C)c4)nccn23)s1.Cc1nn(C)c(C)c1-c1cnc2c(Nc3cccc(N(C)C)c3)nccn12.Cn1cc(-c2cnc3c(Nc4ccc(-n5cncn5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc5ccccc5s4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nnc(C5CC5)s4)nccn23)cn1
• InChI: InChI=1S/C20H23N7.C19H20N6S.C18H15N9.C17H13N7S.C17H16N6O.C15H14N8S/c1-13-18(14(2)26(5)24-13)17-12-22-20-19(21-9-10-27(17)20)23-15-7-6-8-16(11-15)25(3)4;1-12-17(26-13(2)22-12)16-11-21-19-18(20-8-9-25(16)19)23-14-6-5-7-15(10-14)24(3)4;1-25-10-13(8-22-25)16-9-21-18-17(20-6-7-26(16)18)24-14-2-4-15(5-3-14)27-12-19-11-23-27;1-23-10-11(8-20-23)13-9-19-16-15(18-6-7-24(13)16)22-17-21-12-4-2-3-5-14(12)25-17;1-22-11-12(9-20-22)14-10-19-17-16(18-7-8-23(14)17)21-13-5-3-4-6-15(13)24-2;1-22-8-10(6-18-22)11-7-17-13-12(16-4-5-23(11)13)19-15-21-20-14(24-15)9-2-3-9/h6-12H,1-5H3,(H,21,23);5-11H,1-4H3,(H,20,23);2-12H,1H3,(H,20,24);2-10H,1H3,(H,18,21,22);3-11H,1-2H3,(H,18,21);4-9H,2-3H2,1H3,(H,16,19,21)
• InChIKey: AAQZZFAFZUMSRN-UHFFFAOYSA-N
• XLogP: 19.26
• TPSA: 440.40 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 47
• Rotatable Bonds: 23
• Heavy Atoms: 153
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2089.47
LogP ≤ 5	19.26
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	47

Frequently Asked Questions

What is the IUPAC name of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

The IUPAC name of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine (CID 157055173) is 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine.

What is the SMILES notation for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

The canonical SMILES for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine is COc1ccccc1Nc1nccn2c(-c3cnn(C)c3)cnc12.Cc1nc(C)c(-c2cnc3c(Nc4cccc(N(C)C)c4)nccn23)s1.Cc1nn(C)c(C)c1-c1cnc2c(Nc3cccc(N(C)C)c3)nccn12.Cn1cc(-c2cnc3c(Nc4ccc(-n5cncn5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc5ccccc5s4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nnc(C5CC5)s4)nccn23)cn1.

What is the InChIKey of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

The InChIKey is AAQZZFAFZUMSRN-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H23N7.C19H20N6S.C18H15N9.C17H13N7S.C17H16N6O.C15H14N8S/c1-13-18(14(2)26(5)24-13)17-12-22-20-19(21-9-10-27(17)20)23-15-7-6-8-16(11-15)25(3)4;1-12-17(26-13(2)22-12)16-11-21-19-18(20-8-9-25(16)19)23-14-6-5-7-15(10-14)24(3)4;1-25-10-13(8-22-25)16-9-21-18-17(20-6-7-26(16)18)24-14-2-4-15(5-3-14)27-12-19-11-23-27;1-23-10-11(8-20-23)13-9-19-16-15(18-6-7-24(13)16)22-17-21-12-4-2-3-5-14(12)25-17;1-22-11-12(9-20-22)14-10-19-17-16(18-7-8-23(14)17)21-13-5-3-4-6-15(13)24-2;1-22-8-10(6-18-22)11-7-17-13-12(16-4-5-23(11)13)19-15-21-20-14(24-15)9-2-3-9/h6-12H,1-5H3,(H,21,23);5-11H,1-4H3,(H,20,23);2-12H,1H3,(H,20,24);2-10H,1H3,(H,18,21,22);3-11H,1-2H3,(H,18,21);4-9H,2-3H2,1H3,(H,16,19,21).

What are the key properties of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 2089.47 g/mol, XLogP of 19.26, 23 rotatable bonds, 6 hydrogen bond donors, and 47 hydrogen bond acceptors.

Where does this data come from?

All data for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 157055173), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 157055173 — identifiers, structure, computed properties (public domain)

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