5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine

C68H59N29OS2 — CID 158397476

IUPAC5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine
SMILESCOc1ccccc1Nc1nccn2c(-c3cnn(C)c3)cnc12.Cn1cc(-c2cnc3c(Nc4ccnn4-c4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc5ccccc5s4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nnc(C5CC5)s4)nccn23)cn1
InChIInChI=1S/C19H16N8.C17H13N7S.C17H16N6O.C15H14N8S/c1-25-13-14(11-23-25)16-12-21-19-18(20-9-10-26(16)19)24-17-7-8-22-27(17)15-5-3-2-4-6-15;1-23-10-11(8-20-23)13-9-19-16-15(18-6-7-24(13)16)22-17-21-12-4-2-3-5-14(12)25-17;1-22-11-12(9-20-22)14-10-19-17-16(18-7-8-23(14)17)21-13-5-3-4-6-15(13)24-2;1-22-8-10(6-18-22)11-7-17-13-12(16-4-5-23(11)13)19-15-21-20-14(24-15)9-2-3-9/h2-13H,1H3,(H,20,24);2-10H,1H3,(H,18,21,22);3-11H,1-2H3,(H,18,21);4-9H,2-3H2,1H3,(H,16,19,21)
InChIKeyGXROHRLGFCAIOI-UHFFFAOYSA-N
MW1362.56 g/mol
LogP12.03
Rot. Bonds15

About 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine

5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine (PubChem CID 158397476) has the molecular formula C68H59N29OS2 and a molecular weight of 1362.56 g/mol. Its IUPAC name is 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

Compound Name5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine
PubChem CID158397476
Molecular FormulaC68H59N29OS2
Molecular Weight1362.56 g/mol
Exact Mass1361.49
IUPAC Name5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine
SMILESCOc1ccccc1Nc1nccn2c(-c3cnn(C)c3)cnc12.Cn1cc(-c2cnc3c(Nc4ccnn4-c4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc5ccccc5s4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nnc(C5CC5)s4)nccn23)cn1
InChIInChI=1S/C19H16N8.C17H13N7S.C17H16N6O.C15H14N8S/c1-25-13-14(11-23-25)16-12-21-19-18(20-9-10-26(16)19)24-17-7-8-22-27(17)15-5-3-2-4-6-15;1-23-10-11(8-20-23)13-9-19-16-15(18-6-7-24(13)16)22-17-21-12-4-2-3-5-14(12)25-17;1-22-11-12(9-20-22)14-10-19-17-16(18-7-8-23(14)17)21-13-5-3-4-6-15(13)24-2;1-22-8-10(6-18-22)11-7-17-13-12(16-4-5-23(11)13)19-15-21-20-14(24-15)9-2-3-9/h2-13H,1H3,(H,20,24);2-10H,1H3,(H,18,21,22);3-11H,1-2H3,(H,18,21);4-9H,2-3H2,1H3,(H,16,19,21)
InChIKeyGXROHRLGFCAIOI-UHFFFAOYSA-N
XLogP12.03
TPSA305.88 Ų
H-Bond Donors4
H-Bond Acceptors32
Rotatable Bonds15
Heavy Atoms100
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001362.56
LogP ≤ 512.03
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1032

Analyze 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine with MolForge

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Related Compounds

3-(indolizin-7-ylmethyl)-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine;3-(indolizin-6-ylmethyl)-5-pyridin-4-yltriazolo[4,5-b]pyrazine;3-(indolizin-7-ylmethyl)-5-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]triazolo[4,5-b]pyrazine;5-(4-methoxyphenyl)-3-(1H-pyrrolo[3,2-b]pyridin-2-ylmethyl)triazolo[4,5-b]pyrazine;5-(1-methylpyrazol-4-yl)-3-(pyrrolo[1,2-b]pyridazin-2-ylmethyl)triazolo[4,5-b]pyrazine;5-(1-methylpyrazol-4-yl)-3-(1H-pyrrolo[3,2-b]pyridin-2-ylmethyl)triazolo[4,5-b]pyrazine;2-[4-[3-(thieno[2,3-b]pyridin-2-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
CID 158886850
N-[4-(difluoromethoxy)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyridin-2-amine;4,5-dimethyl-N-[6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-2-pyridinyl]-1,3-thiazol-2-amine;4-methyl-N-[6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-2-pyridinyl]-1,3-thiazol-2-amine;5-methyl-N-[6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-2-pyridinyl]-1,3-thiazol-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyridin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyridin-2-amine
CID 159662883
3-(indolizin-7-ylmethyl)-5-[1-(2-methoxyethyl)pyrazol-4-yl]triazolo[4,5-b]pyrazine;3-(indolizin-7-ylmethyl)-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine;3-(indolizin-6-ylmethyl)-5-pyridin-4-yltriazolo[4,5-b]pyrazine;3-(indolizin-7-ylmethyl)-5-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]triazolo[4,5-b]pyrazine;5-(4-methoxyphenyl)-3-(1H-pyrrolo[3,2-b]pyridin-2-ylmethyl)triazolo[4,5-b]pyrazine;5-(1-methylpyrazol-4-yl)-3-(pyrrolo[1,2-b]pyridazin-2-ylmethyl)triazolo[4,5-b]pyrazine;2-[4-[3-(thieno[2,3-b]pyridin-2-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
CID 161995099
2-[3-(8-methoxy-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-propan-2-yl-1H-pyrazol-5-yl]-5-piperazin-1-yl-1,3-thiazole
CID 156321770
5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;1-N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(1,3,5-trimethylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
CID 157055173
N-(3-tert-butyl-1-ethylpyrazol-5-yl)-4-[3-fluoro-4-(4-methylimidazol-1-yl)phenyl]-1,3-thiazol-2-amine;N-(3-tert-butyl-1-ethylpyrazol-5-yl)-4-[4-(4-methylimidazol-1-yl)phenyl]-1,3-thiazol-2-amine;4-[3-fluoro-4-(4-methylimidazol-1-yl)phenyl]-N-(2-methyl-4,5,6,7-tetrahydroindazol-3-yl)-1,3-thiazol-2-amine;4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]-N-(2-methyl-4,5,6,7-tetrahydroindazol-3-yl)-1,3-thiazol-2-amine;4-[6-(4-methylimidazol-1-yl)-3-pyridinyl]-N-(2-methyl-4,5,6,7-tetrahydroindazol-3-yl)-1,3-thiazol-2-amine
CID 157251691
4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-N-(4-methylphenyl)-1,3-thiazol-2-amine;N-(4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine;4-(2-methylimidazo[1,2-a]pyridin-3-yl)-N-(4-methylphenyl)-1,3-thiazol-2-amine
CID 157512188
6-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4-fluoro-N-methyl-N-piperidin-4-yl-1,3-benzothiazol-2-amine;4-fluoro-N-methyl-6-(2-methylimidazo[1,2-b]pyridazin-6-yl)-N-piperidin-4-yl-1,3-benzothiazol-2-amine;4-fluoro-6-(2-methyl-8-phenylmethoxyimidazo[1,2-b]pyridazin-6-yl)-2-piperidin-4-yl-1,3-benzothiazole
CID 157562322
4-fluoro-6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-piperidin-4-yl-1,3-benzothiazole;7-fluoro-5-(8-methoxy-2-methylimidazo[1,2-b]pyridazin-6-yl)-2-piperidin-4-yl-[1,3]thiazolo[5,4-b]pyridine;6-(7-fluoro-2-methylindazol-5-yl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-b]pyrazin-2-amine
CID 157572144
6-(2,7-dimethylindazol-5-yl)-N-(2,2-dimethylpiperidin-4-yl)-N-methyl-1,3-benzothiazol-2-amine;4-fluoro-6-(8-methoxy-2-methylimidazo[1,2-b]pyridazin-6-yl)-2-(1,2,3,6-tetrahydropyridin-4-yl)-1,3-benzothiazole;4-fluoro-6-(2-methylimidazo[1,2-b]pyridazin-6-yl)-2-[(2R)-2-methylpiperidin-4-yl]-1,3-benzothiazole
CID 157581379
N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-piperidin-4-yl-1,2-thiazol-5-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-piperidin-3-yl-1,2-thiazol-5-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-thiazol-5-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]thieno[2,3-c][1,2]thiazol-3-amine;3-(1-methylpyrazol-4-yl)-N-[2-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]imidazo[1,2-a]pyrazin-8-amine
CID 157679150
4-methyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-thiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(pyrrolidin-2-ylmethoxy)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine
CID 157849489

Frequently Asked Questions

What is the IUPAC name of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine?
The IUPAC name of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine (CID 158397476) is 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine.
What is the SMILES notation for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine?
The canonical SMILES for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine is COc1ccccc1Nc1nccn2c(-c3cnn(C)c3)cnc12.Cn1cc(-c2cnc3c(Nc4ccnn4-c4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc5ccccc5s4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nnc(C5CC5)s4)nccn23)cn1.
What is the InChIKey of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine?
The InChIKey is GXROHRLGFCAIOI-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H16N8.C17H13N7S.C17H16N6O.C15H14N8S/c1-25-13-14(11-23-25)16-12-21-19-18(20-9-10-26(16)19)24-17-7-8-22-27(17)15-5-3-2-4-6-15;1-23-10-11(8-20-23)13-9-19-16-15(18-6-7-24(13)16)22-17-21-12-4-2-3-5-14(12)25-17;1-22-11-12(9-20-22)14-10-19-17-16(18-7-8-23(14)17)21-13-5-3-4-6-15(13)24-2;1-22-8-10(6-18-22)11-7-17-13-12(16-4-5-23(11)13)19-15-21-20-14(24-15)9-2-3-9/h2-13H,1H3,(H,20,24);2-10H,1H3,(H,18,21,22);3-11H,1-2H3,(H,18,21);4-9H,2-3H2,1H3,(H,16,19,21).
What are the key properties of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine?
5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 1362.56 g/mol, XLogP of 12.03, 15 rotatable bonds, 4 hydrogen bond donors, and 32 hydrogen bond acceptors.
Where does this data come from?
All data for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 158397476), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).