2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide

C95H74ClN33O4 — CID 157067084

IUPAC2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
SMILESCc1cc(-c2c(C#N)cnc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(C)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(Cl)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(N)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1
InChIInChI=1S/C25H18N8O.C24H20N8O.C23H17ClN8O.C23H19N9O/c1-16-10-17(4-6-28-16)24-19(11-26)13-31-25-20(24)5-9-33(25)15-23(34)32-22-3-2-18(12-30-22)21-14-27-7-8-29-21;1-15-11-17(5-7-26-15)23-19-6-10-32(24(19)30-16(2)29-23)14-22(33)31-21-4-3-18(12-28-21)20-13-25-8-9-27-20;2*1-14-10-15(4-6-26-14)21-17-5-9-32(22(17)31-23(24)30-21)13-20(33)29-19-3-2-16(11-28-19)18-12-25-7-8-27-18/h2-10,12-14H,15H2,1H3,(H,30,32,34);3-13H,14H2,1-2H3,(H,28,31,33);2-12H,13H2,1H3,(H,28,29,33);2-12H,13H2,1H3,(H2,24,30,31)(H,28,29,33)
InChIKeyABZSCPXYIHTOCP-UHFFFAOYSA-N
MW1777.32 g/mol
LogP14.19
Rot. Bonds20

About 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide

2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide (PubChem CID 157067084) has the molecular formula C95H74ClN33O4 and a molecular weight of 1777.32 g/mol. Its IUPAC name is 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide.

Molecular Properties

Compound Name2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
PubChem CID157067084
Molecular FormulaC95H74ClN33O4
Molecular Weight1777.32 g/mol
Exact Mass1775.63
IUPAC Name2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
SMILESCc1cc(-c2c(C#N)cnc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(C)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(Cl)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(N)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1
InChIInChI=1S/C25H18N8O.C24H20N8O.C23H17ClN8O.C23H19N9O/c1-16-10-17(4-6-28-16)24-19(11-26)13-31-25-20(24)5-9-33(25)15-23(34)32-22-3-2-18(12-30-22)21-14-27-7-8-29-21;1-15-11-17(5-7-26-15)23-19-6-10-32(24(19)30-16(2)29-23)14-22(33)31-21-4-3-18(12-28-21)20-13-25-8-9-27-20;2*1-14-10-15(4-6-26-14)21-17-5-9-32(22(17)31-23(24)30-21)13-20(33)29-19-3-2-16(11-28-19)18-12-25-7-8-27-18/h2-10,12-14H,15H2,1H3,(H,30,32,34);3-13H,14H2,1-2H3,(H,28,31,33);2-12H,13H2,1H3,(H,28,29,33);2-12H,13H2,1H3,(H2,24,30,31)(H,28,29,33)
InChIKeyABZSCPXYIHTOCP-UHFFFAOYSA-N
XLogP14.19
TPSA482.40 Ų
H-Bond Donors5
H-Bond Acceptors33
Rotatable Bonds20
Heavy Atoms133
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001777.32
LogP ≤ 514.19
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1033

Analyze 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide with MolForge

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Launch Full Analysis

Related Compounds

US10202375, Example 2
CID 121271673
US10202375, Example 21
CID 121280703
US9433622, Dmx-128
CID 118620021
US10202375, Example 5
CID 121271659
US10202375, Example 3
CID 121271678
US10202375, Example 1
CID 121271682
US10202375, Example 11
CID 121280670
US10202375, Example 10
CID 121280695
US10202375, Example 12
CID 121280697
US10202375, Example 8
CID 121280699
US10202375, Example 30
CID 121271669
US10202375, Example 20
CID 121280704

Frequently Asked Questions

What is the IUPAC name of 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
The IUPAC name of 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide (CID 157067084) is 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide.
What is the SMILES notation for 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
The canonical SMILES for 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide is Cc1cc(-c2c(C#N)cnc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(C)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(Cl)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2nc(N)nc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.
What is the InChIKey of 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
The InChIKey is ABZSCPXYIHTOCP-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H18N8O.C24H20N8O.C23H17ClN8O.C23H19N9O/c1-16-10-17(4-6-28-16)24-19(11-26)13-31-25-20(24)5-9-33(25)15-23(34)32-22-3-2-18(12-30-22)21-14-27-7-8-29-21;1-15-11-17(5-7-26-15)23-19-6-10-32(24(19)30-16(2)29-23)14-22(33)31-21-4-3-18(12-28-21)20-13-25-8-9-27-20;2*1-14-10-15(4-6-26-14)21-17-5-9-32(22(17)31-23(24)30-21)13-20(33)29-19-3-2-16(11-28-19)18-12-25-7-8-27-18/h2-10,12-14H,15H2,1H3,(H,30,32,34);3-13H,14H2,1-2H3,(H,28,31,33);2-12H,13H2,1H3,(H,28,29,33);2-12H,13H2,1H3,(H2,24,30,31)(H,28,29,33).
What are the key properties of 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide has a molecular weight of 1777.32 g/mol, XLogP of 14.19, 20 rotatable bonds, 5 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[2-amino-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-chloro-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[2-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide is sourced from PubChem (CID 157067084), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).