5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide

C₁₂₁H₁₃₃F₂N₃₇O₁₁S₉ — CID 157085694

About 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide

5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide (PubChem CID 157085694) has the molecular formula C₁₂₁H₁₃₃F₂N₃₇O₁₁S₉ and a molecular weight of 2608.24 g/mol. Its IUPAC name is 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide.

Molecular Properties

• Compound Name: 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide
• PubChem CID: 157085694
• Molecular Formula: C₁₂₁H₁₃₃F₂N₃₇O₁₁S₉
• Molecular Weight: 2608.24 g/mol
• Exact Mass: 2605.84
• IUPAC Name: 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide
• SMILES: C#Cc1ccc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1.CCCCCC(=O)NC1CN(C(=O)c2sc3nnc(C)c(C)c3c2N)C1.Cc1cnc(N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)nc1.Cc1nnc2sc(C(=O)N3CC(F)(c4ccccc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)N3CC(NS(=O)(=O)c4cn(C)cn4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(c4nccs4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NCc3ccc(OCC(C)F)cc3)c(N)c2c1C
• InChI: InChI=1S/C19H21FN4O2S.C18H17FN4OS.C18H25N5O2S.C18H16N4OS.C17H19N7OS.C16H19N7O3S2.C15H16N6OS2/c1-10(20)9-26-14-6-4-13(5-7-14)8-22-18(25)17-16(21)15-11(2)12(3)23-24-19(15)27-17;1-10-11(2)21-22-16-13(10)14(20)15(25-16)17(24)23-8-18(19,9-23)12-6-4-3-5-7-12;1-4-5-6-7-13(24)20-12-8-23(9-12)18(25)16-15(19)14-10(2)11(3)21-22-17(14)26-16;1-4-12-5-7-13(8-6-12)9-20-17(23)16-15(19)14-10(2)11(3)21-22-18(14)24-16;1-8-4-19-17(20-5-8)24-6-11(7-24)21-15(25)14-13(18)12-9(2)10(3)22-23-16(12)26-14;1-8-9(2)19-20-15-12(8)13(17)14(27-15)16(24)23-4-10(5-23)21-28(25,26)11-6-22(3)7-18-11;1-7-8(2)19-20-14-10(7)11(16)12(24-14)13(22)18-9-5-21(6-9)15-17-3-4-23-15/h4-7,10H,8-9,21H2,1-3H3,(H,22,25);3-7H,8-9,20H2,1-2H3;12H,4-9,19H2,1-3H3,(H,20,24);1,5-8H,9,19H2,2-3H3,(H,20,23);4-5,11H,6-7,18H2,1-3H3,(H,21,25);6-7,10,21H,4-5,17H2,1-3H3;3-4,9H,5-6,16H2,1-2H3,(H,18,22)
• InChIKey: AEBGGBQDPMYMSB-UHFFFAOYSA-N
• XLogP: 15.98
• TPSA: 687.40 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 47
• Rotatable Bonds: 27
• Heavy Atoms: 180
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2608.24
LogP ≤ 5	15.98
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	47

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide?

The IUPAC name of 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide (CID 157085694) is 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide.

What is the SMILES notation for 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide?

The canonical SMILES for 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide is C#Cc1ccc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1.CCCCCC(=O)NC1CN(C(=O)c2sc3nnc(C)c(C)c3c2N)C1.Cc1cnc(N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)nc1.Cc1nnc2sc(C(=O)N3CC(F)(c4ccccc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)N3CC(NS(=O)(=O)c4cn(C)cn4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(c4nccs4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NCc3ccc(OCC(C)F)cc3)c(N)c2c1C.

What is the InChIKey of 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide?

The InChIKey is AEBGGBQDPMYMSB-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H21FN4O2S.C18H17FN4OS.C18H25N5O2S.C18H16N4OS.C17H19N7OS.C16H19N7O3S2.C15H16N6OS2/c1-10(20)9-26-14-6-4-13(5-7-14)8-22-18(25)17-16(21)15-11(2)12(3)23-24-19(15)27-17;1-10-11(2)21-22-16-13(10)14(20)15(25-16)17(24)23-8-18(19,9-23)12-6-4-3-5-7-12;1-4-5-6-7-13(24)20-12-8-23(9-12)18(25)16-15(19)14-10(2)11(3)21-22-17(14)26-16;1-4-12-5-7-13(8-6-12)9-20-17(23)16-15(19)14-10(2)11(3)21-22-18(14)24-16;1-8-4-19-17(20-5-8)24-6-11(7-24)21-15(25)14-13(18)12-9(2)10(3)22-23-16(12)26-14;1-8-9(2)19-20-15-12(8)13(17)14(27-15)16(24)23-4-10(5-23)21-28(25,26)11-6-22(3)7-18-11;1-7-8(2)19-20-14-10(7)11(16)12(24-14)13(22)18-9-5-21(6-9)15-17-3-4-23-15/h4-7,10H,8-9,21H2,1-3H3,(H,22,25);3-7H,8-9,20H2,1-2H3;12H,4-9,19H2,1-3H3,(H,20,24);1,5-8H,9,19H2,2-3H3,(H,20,23);4-5,11H,6-7,18H2,1-3H3,(H,21,25);6-7,10,21H,4-5,17H2,1-3H3;3-4,9H,5-6,16H2,1-2H3,(H,18,22).

What are the key properties of 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide?

5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide has a molecular weight of 2608.24 g/mol, XLogP of 15.98, 27 rotatable bonds, 13 hydrogen bond donors, and 47 hydrogen bond acceptors.

Where does this data come from?

All data for 5-amino-3,4-dimethyl-N-[1-(5-methylpyrimidin-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(1,3-thiazol-2-yl)azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]hexanamide;N-[1-(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)azetidin-3-yl]-1-methylimidazole-4-sulfonamide;(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(3-fluoro-3-phenylazetidin-1-yl)methanone;5-amino-N-[(4-ethynylphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(2-fluoropropoxy)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide is sourced from PubChem (CID 157085694), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 157085694 — identifiers, structure, computed properties (public domain)

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