N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one

C135H138BrCl4F14N35O5 — CID 157088240

About N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one

N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one (PubChem CID 157088240) has the molecular formula C135H138BrCl4F14N35O5 and a molecular weight of 2818.52 g/mol. Its IUPAC name is N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one.

Molecular Properties

• Compound Name: N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one
• PubChem CID: 157088240
• Molecular Formula: C135H138BrCl4F14N35O5
• Molecular Weight: 2818.52 g/mol
• Exact Mass: 2813.93
• IUPAC Name: N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one
• SMILES: CC(C)(C)c1ccc(Nc2nc(=O)[nH]c3c2CCN(c2ncccc2C(F)(F)F)C3)cc1.CC1Cc2c(nc(N(C)C)nc2Nc2ccc(C(F)(F)F)nc2)CN1c1ncccc1Cl.CC1c2nc(CCN3CCOCC3)nc(Nc3ccc(Br)nc3)c2CCN1c1ccc(Cl)cn1.CCOCCNc1nc2c(c(Nc3ccc(OC(F)F)cc3)n1)CCN(c1ncccc1Cl)C2.CN1CCCc2ccc(Nc3nccc4c3CCN(c3ncccc3Cl)C4)cc21.Cn1c2c(c(Nc3ccc(C(F)(F)F)cc3)nc1=O)CCN(c1ncccc1C(F)(F)F)C2
• InChI: InChI=1S/C24H27BrClN7O.C23H25ClF2N6O2.C23H24ClN5.C23H24F3N5O.C21H21ClF3N7.C21H17F6N5O/c1-16-23-19(6-9-33(16)22-5-2-17(26)14-28-22)24(29-18-3-4-20(25)27-15-18)31-21(30-23)7-8-32-10-12-34-13-11-32;1-2-33-13-11-28-23-30-19-14-32(21-18(24)4-3-10-27-21)12-9-17(19)20(31-23)29-15-5-7-16(8-6-15)34-22(25)26;1-28-12-3-4-16-6-7-18(14-21(16)28)27-22-19-9-13-29(15-17(19)8-11-25-22)23-20(24)5-2-10-26-23;1-22(2,3)14-6-8-15(9-7-14)28-19-16-10-12-31(13-18(16)29-21(32)30-19)20-17(23(24,25)26)5-4-11-27-20;1-12-9-14-16(11-32(12)19-15(22)5-4-8-26-19)29-20(31(2)3)30-18(14)28-13-6-7-17(27-10-13)21(23,24)25;1-31-16-11-32(18-15(21(25,26)27)3-2-9-28-18)10-8-14(16)17(30-19(31)33)29-13-6-4-12(5-7-13)20(22,23)24/h2-5,14-16H,6-13H2,1H3,(H,29,30,31);3-8,10,22H,2,9,11-14H2,1H3,(H2,28,29,30,31);2,5-8,10-11,14H,3-4,9,12-13,15H2,1H3,(H,25,27);4-9,11H,10,12-13H2,1-3H3,(H2,28,29,30,32);4-8,10,12H,9,11H2,1-3H3,(H,28,29,30);2-7,9H,8,10-11H2,1H3,(H,29,30,33)
• InChIKey: AEIONMZFKNIDGR-UHFFFAOYSA-N
• XLogP: 28.13
• TPSA: 415.05 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 39
• Rotatable Bonds: 29
• Heavy Atoms: 194
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2818.52
LogP ≤ 5	28.13
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	39

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one?

The IUPAC name of N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one (CID 157088240) is N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one.

What is the SMILES notation for N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one?

The canonical SMILES for N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one is CC(C)(C)c1ccc(Nc2nc(=O)[nH]c3c2CCN(c2ncccc2C(F)(F)F)C3)cc1.CC1Cc2c(nc(N(C)C)nc2Nc2ccc(C(F)(F)F)nc2)CN1c1ncccc1Cl.CC1c2nc(CCN3CCOCC3)nc(Nc3ccc(Br)nc3)c2CCN1c1ccc(Cl)cn1.CCOCCNc1nc2c(c(Nc3ccc(OC(F)F)cc3)n1)CCN(c1ncccc1Cl)C2.CN1CCCc2ccc(Nc3nccc4c3CCN(c3ncccc3Cl)C4)cc21.Cn1c2c(c(Nc3ccc(C(F)(F)F)cc3)nc1=O)CCN(c1ncccc1C(F)(F)F)C2.

What is the InChIKey of N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one?

The InChIKey is AEIONMZFKNIDGR-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H27BrClN7O.C23H25ClF2N6O2.C23H24ClN5.C23H24F3N5O.C21H21ClF3N7.C21H17F6N5O/c1-16-23-19(6-9-33(16)22-5-2-17(26)14-28-22)24(29-18-3-4-20(25)27-15-18)31-21(30-23)7-8-32-10-12-34-13-11-32;1-2-33-13-11-28-23-30-19-14-32(21-18(24)4-3-10-27-21)12-9-17(19)20(31-23)29-15-5-7-16(8-6-15)34-22(25)26;1-28-12-3-4-16-6-7-18(14-21(16)28)27-22-19-9-13-29(15-17(19)8-11-25-22)23-20(24)5-2-10-26-23;1-22(2,3)14-6-8-15(9-7-14)28-19-16-10-12-31(13-18(16)29-21(32)30-19)20-17(23(24,25)26)5-4-11-27-20;1-12-9-14-16(11-32(12)19-15(22)5-4-8-26-19)29-20(31(2)3)30-18(14)28-13-6-7-17(27-10-13)21(23,24)25;1-31-16-11-32(18-15(21(25,26)27)3-2-9-28-18)10-8-14(16)17(30-19(31)33)29-13-6-4-12(5-7-13)20(22,23)24/h2-5,14-16H,6-13H2,1H3,(H,29,30,31);3-8,10,22H,2,9,11-14H2,1H3,(H2,28,29,30,31);2,5-8,10-11,14H,3-4,9,12-13,15H2,1H3,(H,25,27);4-9,11H,10,12-13H2,1-3H3,(H2,28,29,30,32);4-8,10,12H,9,11H2,1-3H3,(H,28,29,30);2-7,9H,8,10-11H2,1H3,(H,29,30,33).

What are the key properties of N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one?

N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one has a molecular weight of 2818.52 g/mol, XLogP of 28.13, 29 rotatable bonds, 8 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for N-(6-bromo-3-pyridinyl)-7-(5-chloro-2-pyridinyl)-8-methyl-2-(2-morpholin-4-ylethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;4-(4-tert-butylanilino)-7-[3-(trifluoromethyl)-2-pyridinyl]-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-2-one;7-(3-chloro-2-pyridinyl)-4-N-[4-(difluoromethoxy)phenyl]-2-N-(2-ethoxyethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;6-(3-chloro-2-pyridinyl)-N-(1-methyl-3,4-dihydro-2H-quinolin-7-yl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-2-N,2-N,6-trimethyl-4-N-[6-(trifluoromethyl)-3-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-2,4-diamine;1-methyl-4-[4-(trifluoromethyl)anilino]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-one is sourced from PubChem (CID 157088240), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).