2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine

C120H125Br2Cl2F12N23O3 — CID 157213185

About 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine

2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine (PubChem CID 157213185) has the molecular formula C120H125Br2Cl2F12N23O3 and a molecular weight of 2396.17 g/mol. Its IUPAC name is 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine.

Molecular Properties

• Compound Name: 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine
• PubChem CID: 157213185
• Molecular Formula: C120H125Br2Cl2F12N23O3
• Molecular Weight: 2396.17 g/mol
• Exact Mass: 2391.79
• IUPAC Name: 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine
• SMILES: CC1c2cc(CCN3CCNCC3)nc(Nc3ccc(Br)nc3)c2CCN1c1ccccc1Cl.CCN(CC)c1ccc(Nc2nccc3c2CC(C)N(c2ccccc2OC)C3)cc1Br.COCCNc1cc2c(c(Nc3ccc(OC(F)(F)F)cc3)n1)CCN(c1ccccc1Cl)C2.Cc1ccccc1N1CCc2c(cc(N(C)C)nc2Nc2ccc(C(F)(F)F)nc2)C1.FC(F)(F)c1ccc(Nc2nccc3c2CCN(c2ccccc2C(F)(F)F)C3)nc1
• InChI: InChI=1S/C26H30BrClN6.C26H31BrN4O.C24H24ClF3N4O2.C23H24F3N5.C21H16F6N4/c1-18-22-16-19(8-12-33-14-10-29-11-15-33)31-26(32-20-6-7-25(27)30-17-20)21(22)9-13-34(18)24-5-3-2-4-23(24)28;1-5-30(6-2)23-12-11-20(16-22(23)27)29-26-21-15-18(3)31(17-19(21)13-14-28-26)24-9-7-8-10-25(24)32-4;1-33-13-11-29-22-14-16-15-32(21-5-3-2-4-20(21)25)12-10-19(16)23(31-22)30-17-6-8-18(9-7-17)34-24(26,27)28;1-15-6-4-5-7-19(15)31-11-10-18-16(14-31)12-21(30(2)3)29-22(18)28-17-8-9-20(27-13-17)23(24,25)26;22-20(23,24)14-5-6-18(29-11-14)30-19-15-8-10-31(12-13(15)7-9-28-19)17-4-2-1-3-16(17)21(25,26)27/h2-7,16-18,29H,8-15H2,1H3,(H,31,32);7-14,16,18H,5-6,15,17H2,1-4H3,(H,28,29);2-9,14H,10-13,15H2,1H3,(H2,29,30,31);4-9,12-13H,10-11,14H2,1-3H3,(H,28,29);1-7,9,11H,8,10,12H2,(H,28,29,30)
• InChIKey: ASCUGPOZSGHVCL-UHFFFAOYSA-N
• XLogP: 28.60
• TPSA: 240.94 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 26
• Rotatable Bonds: 28
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2396.17
LogP ≤ 5	28.60
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}, {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine?

The IUPAC name of 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine (CID 157213185) is 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine.

What is the SMILES notation for 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine?

The canonical SMILES for 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine is CC1c2cc(CCN3CCNCC3)nc(Nc3ccc(Br)nc3)c2CCN1c1ccccc1Cl.CCN(CC)c1ccc(Nc2nccc3c2CC(C)N(c2ccccc2OC)C3)cc1Br.COCCNc1cc2c(c(Nc3ccc(OC(F)(F)F)cc3)n1)CCN(c1ccccc1Cl)C2.Cc1ccccc1N1CCc2c(cc(N(C)C)nc2Nc2ccc(C(F)(F)F)nc2)C1.FC(F)(F)c1ccc(Nc2nccc3c2CCN(c2ccccc2C(F)(F)F)C3)nc1.

What is the InChIKey of 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine?

The InChIKey is ASCUGPOZSGHVCL-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H30BrClN6.C26H31BrN4O.C24H24ClF3N4O2.C23H24F3N5.C21H16F6N4/c1-18-22-16-19(8-12-33-14-10-29-11-15-33)31-26(32-20-6-7-25(27)30-17-20)21(22)9-13-34(18)24-5-3-2-4-23(24)28;1-5-30(6-2)23-12-11-20(16-22(23)27)29-26-21-15-18(3)31(17-19(21)13-14-28-26)24-9-7-8-10-25(24)32-4;1-33-13-11-29-22-14-16-15-32(21-5-3-2-4-20(21)25)12-10-19(16)23(31-22)30-17-6-8-18(9-7-17)34-24(26,27)28;1-15-6-4-5-7-19(15)31-11-10-18-16(14-31)12-21(30(2)3)29-22(18)28-17-8-9-20(27-13-17)23(24,25)26;22-20(23,24)14-5-6-18(29-11-14)30-19-15-8-10-31(12-13(15)7-9-28-19)17-4-2-1-3-16(17)21(25,26)27/h2-7,16-18,29H,8-15H2,1H3,(H,31,32);7-14,16,18H,5-6,15,17H2,1-4H3,(H,28,29);2-9,14H,10-13,15H2,1H3,(H2,29,30,31);4-9,12-13H,10-11,14H2,1-3H3,(H,28,29);1-7,9,11H,8,10,12H2,(H,28,29,30).

What are the key properties of 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine?

2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine has a molecular weight of 2396.17 g/mol, XLogP of 28.60, 28 rotatable bonds, 7 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 2-bromo-1-N,1-N-diethyl-4-N-[6-(2-methoxyphenyl)-7-methyl-7,8-dihydro-5H-2,6-naphthyridin-1-yl]benzene-1,4-diamine;N-(6-bromo-3-pyridinyl)-6-(2-chlorophenyl)-5-methyl-3-(2-piperazin-1-ylethyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;6-(2-chlorophenyl)-3-N-(2-methoxyethyl)-1-N-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;3-N,3-N-dimethyl-6-(2-methylphenyl)-1-N-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridine-1,3-diamine;6-[2-(trifluoromethyl)phenyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine is sourced from PubChem (CID 157213185), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).