2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

C84H72F6N40O6 — CID 157091967

IUPAC2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCn1cncc1-c1ccncc1NC(=O)c1c(N)nn2cc(F)cnc12.COc1cncc(NC(=O)c2c(N)nn3cc(F)cnc23)c1-c1cncn1C.Cc1ncc(-c2ccncc2NC(=O)c2c(N)nn3cc(F)cnc23)n1C.Cc1ncn(C)c1-c1ccncc1NC(=O)c1c(N)nn2cc(F)cnc12.Cn1cncc1-c1c(F)cncc1NC(=O)c1c(N)nn2cc(F)cnc12
InChIInChI=1S/C17H15FN8O2.3C17H15FN8O.C16H12F2N8O/c1-25-8-21-5-11(25)13-10(4-20-6-12(13)28-2)23-17(27)14-15(19)24-26-7-9(18)3-22-16(14)26;1-9-21-7-13(25(9)2)11-3-4-20-6-12(11)23-17(27)14-15(19)24-26-8-10(18)5-22-16(14)26;1-9-14(25(2)8-22-9)11-3-4-20-6-12(11)23-17(27)13-15(19)24-26-7-10(18)5-21-16(13)26;1-2-25-9-21-7-13(25)11-3-4-20-6-12(11)23-17(27)14-15(19)24-26-8-10(18)5-22-16(14)26;1-25-7-21-5-11(25)12-9(18)3-20-4-10(12)23-16(27)13-14(19)24-26-6-8(17)2-22-15(13)26/h3-8H,1-2H3,(H2,19,24)(H,23,27);2*3-8H,1-2H3,(H2,19,24)(H,23,27);3-9H,2H2,1H3,(H2,19,24)(H,23,27);2-7H,1H3,(H2,19,24)(H,23,27)
InChIKeyAETODTJTQROTBJ-UHFFFAOYSA-N
MW1851.76 g/mol
LogP8.74
Rot. Bonds17

About 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 157091967) has the molecular formula C84H72F6N40O6 and a molecular weight of 1851.76 g/mol. Its IUPAC name is 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID157091967
Molecular FormulaC84H72F6N40O6
Molecular Weight1851.76 g/mol
Exact Mass1850.65
IUPAC Name2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCn1cncc1-c1ccncc1NC(=O)c1c(N)nn2cc(F)cnc12.COc1cncc(NC(=O)c2c(N)nn3cc(F)cnc23)c1-c1cncn1C.Cc1ncc(-c2ccncc2NC(=O)c2c(N)nn3cc(F)cnc23)n1C.Cc1ncn(C)c1-c1ccncc1NC(=O)c1c(N)nn2cc(F)cnc12.Cn1cncc1-c1c(F)cncc1NC(=O)c1c(N)nn2cc(F)cnc12
InChIInChI=1S/C17H15FN8O2.3C17H15FN8O.C16H12F2N8O/c1-25-8-21-5-11(25)13-10(4-20-6-12(13)28-2)23-17(27)14-15(19)24-26-7-9(18)3-22-16(14)26;1-9-21-7-13(25(9)2)11-3-4-20-6-12(11)23-17(27)14-15(19)24-26-8-10(18)5-22-16(14)26;1-9-14(25(2)8-22-9)11-3-4-20-6-12(11)23-17(27)13-15(19)24-26-7-10(18)5-21-16(13)26;1-2-25-9-21-7-13(25)11-3-4-20-6-12(11)23-17(27)14-15(19)24-26-8-10(18)5-22-16(14)26;1-25-7-21-5-11(25)12-9(18)3-20-4-10(12)23-16(27)13-14(19)24-26-6-8(17)2-22-15(13)26/h3-8H,1-2H3,(H2,19,24)(H,23,27);2*3-8H,1-2H3,(H2,19,24)(H,23,27);3-9H,2H2,1H3,(H2,19,24)(H,23,27);2-7H,1H3,(H2,19,24)(H,23,27)
InChIKeyAETODTJTQROTBJ-UHFFFAOYSA-N
XLogP8.74
TPSA589.33 Ų
H-Bond Donors10
H-Bond Acceptors41
Rotatable Bonds17
Heavy Atoms136
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001851.76
LogP ≤ 58.74
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1041

Analyze 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[1-(2-hydroxy-2-methylpropyl)-3-[5-methoxy-2-(trifluoromethyl)pyridin-4-yl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 66851039
2-amino-N-[4-[[6-[(dimethylamino)methyl]-3-pyridinyl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287699
2-amino-6-fluoro-N-(5-methoxy-4-pyridin-3-yl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90198963
2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199030
2-amino-6-fluoro-N-[5-methoxy-4-[3-(2-methoxyethyl)imidazol-4-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 134335678
US11691963, Example I-127
CID 157041891
US11691963, Example I-128-a
CID 157042147
US11691963, Example I-126
CID 157042171
US11691963, Example I-128-b
CID 157042259
US11691963, Example I-125
CID 157042337
US11691963, Example I-124
CID 157042494
US11691963, Example I-148-b
CID 157041832

Frequently Asked Questions

What is the IUPAC name of 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 157091967) is 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is CCn1cncc1-c1ccncc1NC(=O)c1c(N)nn2cc(F)cnc12.COc1cncc(NC(=O)c2c(N)nn3cc(F)cnc23)c1-c1cncn1C.Cc1ncc(-c2ccncc2NC(=O)c2c(N)nn3cc(F)cnc23)n1C.Cc1ncn(C)c1-c1ccncc1NC(=O)c1c(N)nn2cc(F)cnc12.Cn1cncc1-c1c(F)cncc1NC(=O)c1c(N)nn2cc(F)cnc12.
What is the InChIKey of 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is AETODTJTQROTBJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H15FN8O2.3C17H15FN8O.C16H12F2N8O/c1-25-8-21-5-11(25)13-10(4-20-6-12(13)28-2)23-17(27)14-15(19)24-26-7-9(18)3-22-16(14)26;1-9-21-7-13(25(9)2)11-3-4-20-6-12(11)23-17(27)14-15(19)24-26-8-10(18)5-22-16(14)26;1-9-14(25(2)8-22-9)11-3-4-20-6-12(11)23-17(27)13-15(19)24-26-7-10(18)5-21-16(13)26;1-2-25-9-21-7-13(25)11-3-4-20-6-12(11)23-17(27)14-15(19)24-26-8-10(18)5-22-16(14)26;1-25-7-21-5-11(25)12-9(18)3-20-4-10(12)23-16(27)13-14(19)24-26-6-8(17)2-22-15(13)26/h3-8H,1-2H3,(H2,19,24)(H,23,27);2*3-8H,1-2H3,(H2,19,24)(H,23,27);3-9H,2H2,1H3,(H2,19,24)(H,23,27);2-7H,1H3,(H2,19,24)(H,23,27).
What are the key properties of 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 1851.76 g/mol, XLogP of 8.74, 17 rotatable bonds, 10 hydrogen bond donors, and 41 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-N-[4-(2,3-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3,5-dimethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(3-ethylimidazol-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-fluoro-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 157091967), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).