N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide

C127H140F4N34O11 — CID 157103535

IUPACN-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCc1cc(-c2cccc(F)c2)nc2c(C(=O)NC(C)(C)C)ncn12.Cc1cc(-c2ncc[nH]2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(Oc2cccc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2ccccn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2cccnc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2ccncc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12
InChIInChI=1S/C19H25F2N5O.C19H19FN4O2.C18H19FN4O.3C18H19N5O2.C17H20N6O/c1-12-10-14(25-8-6-19(20,21)7-9-25)23-16-15(22-11-26(12)16)17(27)24-18(2,3)13-4-5-13;1-11-8-16(26-15-5-3-4-14(20)9-15)23-18-17(21-10-24(11)18)19(25)22-12(2)13-6-7-13;1-11-8-14(12-6-5-7-13(19)9-12)21-16-15(20-10-23(11)16)17(24)22-18(2,3)4;1-11-9-15(25-14-5-7-19-8-6-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-3-4-13;1-11-8-15(25-14-4-3-7-19-9-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-5-6-13;1-11-9-15(25-14-5-3-4-8-19-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-6-7-13;1-10-8-12(14-18-6-7-19-14)21-15-13(20-9-23(10)15)16(24)22-17(2,3)11-4-5-11/h10-11,13H,4-9H2,1-3H3,(H,24,27);3-5,8-10,12-13H,6-7H2,1-2H3,(H,22,25);5-10H,1-4H3,(H,22,24);5-10,12-13H,3-4H2,1-2H3,(H,21,24);3-4,7-10,12-13H,5-6H2,1-2H3,(H,21,24);3-5,8-10,12-13H,6-7H2,1-2H3,(H,21,24);6-9,11H,4-5H2,1-3H3,(H,18,19)(H,22,24)/t;12-;;3*12-;/m.0.000./s1
InChIKeyAGAPFVYIZCTMPG-WCFMXVFCSA-N
MW2394.74 g/mol
LogP20.67
Rot. Bonds30

About N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide

N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide (PubChem CID 157103535) has the molecular formula C127H140F4N34O11 and a molecular weight of 2394.74 g/mol. Its IUPAC name is N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide.

Molecular Properties

Compound NameN-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide
PubChem CID157103535
Molecular FormulaC127H140F4N34O11
Molecular Weight2394.74 g/mol
Exact Mass2393.14
IUPAC NameN-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCc1cc(-c2cccc(F)c2)nc2c(C(=O)NC(C)(C)C)ncn12.Cc1cc(-c2ncc[nH]2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(Oc2cccc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2ccccn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2cccnc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2ccncc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12
InChIInChI=1S/C19H25F2N5O.C19H19FN4O2.C18H19FN4O.3C18H19N5O2.C17H20N6O/c1-12-10-14(25-8-6-19(20,21)7-9-25)23-16-15(22-11-26(12)16)17(27)24-18(2,3)13-4-5-13;1-11-8-16(26-15-5-3-4-14(20)9-15)23-18-17(21-10-24(11)18)19(25)22-12(2)13-6-7-13;1-11-8-14(12-6-5-7-13(19)9-12)21-16-15(20-10-23(11)16)17(24)22-18(2,3)4;1-11-9-15(25-14-5-7-19-8-6-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-3-4-13;1-11-8-15(25-14-4-3-7-19-9-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-5-6-13;1-11-9-15(25-14-5-3-4-8-19-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-6-7-13;1-10-8-12(14-18-6-7-19-14)21-15-13(20-9-23(10)15)16(24)22-17(2,3)11-4-5-11/h10-11,13H,4-9H2,1-3H3,(H,24,27);3-5,8-10,12-13H,6-7H2,1-2H3,(H,22,25);5-10H,1-4H3,(H,22,24);5-10,12-13H,3-4H2,1-2H3,(H,21,24);3-4,7-10,12-13H,5-6H2,1-2H3,(H,21,24);3-5,8-10,12-13H,6-7H2,1-2H3,(H,21,24);6-9,11H,4-5H2,1-3H3,(H,18,19)(H,22,24)/t;12-;;3*12-;/m.0.000./s1
InChIKeyAGAPFVYIZCTMPG-WCFMXVFCSA-N
XLogP20.67
TPSA522.54 Ų
H-Bond Donors8
H-Bond Acceptors37
Rotatable Bonds30
Heavy Atoms176
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002394.74
LogP ≤ 520.67
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1037

Analyze N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide with MolForge

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Related Compounds

3-amino-N-[3-(4-amino-3-methylpiperidin-1-yl)-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[3,6-bis(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-6-(6-fluoroquinazolin-4-yl)-N-(3-piperidin-1-yl-2-pyridinyl)pyrazine-2-carboxamide;3-amino-6-[6-morpholin-4-yl-3-(trifluoromethyl)-2-pyridinyl]-N-(3-piperidin-1-yl-2-pyridinyl)pyrazine-2-carboxamide;methanamine
CID 157362098
3-amino-N-[3-(4-amino-3-methylpiperidin-1-yl)-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[3,6-bis(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide
CID 157562787
1-[(2S)-2-[8-amino-1-[4-[(5-fluoro-2-pyridinyl)methoxy]phenyl]imidazo[1,5-a]pyrazin-3-yl]pyrrolidin-1-yl]prop-2-en-1-one;1-[(2S)-2-[8-amino-1-[4-[(5-methoxy-2-pyridinyl)methoxy]phenyl]imidazo[1,5-a]pyrazin-3-yl]pyrrolidin-1-yl]prop-2-en-1-one;1-[(2S)-2-[8-amino-1-[4-(pyridin-2-ylmethoxy)phenyl]imidazo[1,5-a]pyrazin-3-yl]pyrrolidin-1-yl]prop-2-en-1-one;1-[(2S)-2-[8-amino-1-[4-[[5-(trifluoromethyl)-2-pyridinyl]methoxy]phenyl]imidazo[1,5-a]pyrazin-3-yl]pyrrolidin-1-yl]prop-2-en-1-one
CID 157567699
N-tert-butyl-2-(3-chlorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(3-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-cyclobutyloxy-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-cyclobutyloxy-N-(dicyclopropylmethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-cyclopropyloxy-N-(dicyclopropylmethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(3-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide
CID 157778439
(1S,5R)-N-[1-[(4-cyclopropyl-3-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(1-imidazo[1,2-a]pyridin-8-yloxy-2-methylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-(2-methylpyrazol-3-yl)oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[4-(trifluoromethyl)pyridazin-3-yl]oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 158274742
ethyl 4-[4-(4-fluorophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)imidazol-1-yl]piperidine-1-carboxylate;4-[5-(4-fluorophenyl)-3-(furan-2-ylmethyl)imidazol-4-yl]-1H-pyrrolo[2,3-b]pyridine;4-[5-(4-fluorophenyl)-3-(furan-3-ylmethyl)imidazol-4-yl]-1H-pyrrolo[2,3-b]pyridine;4-[4-(4-fluorophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)imidazol-1-yl]-N,N-dimethylcyclohexan-1-amine;4-[5-(4-fluorophenyl)-3-[3-(trifluoromethoxy)propyl]imidazol-4-yl]-1H-pyrrolo[2,3-b]pyridine
CID 158403835
2-(2-cyano-3-methoxyphenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyano-2-methoxyphenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-cyano-3-methoxyphenyl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyano-2-methoxyphenyl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyano-2-methoxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-fluoro-2-methoxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158461084
cyclopropyl-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;(2,2-difluorocyclopropyl)-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;[(2R,6S)-2,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]-(1-propan-2-ylpyrazol-3-yl)methanone;6-phenoxy-3-[4-[(3S)-3-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyridine;6-phenoxy-3-[4-[(3R)-3-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyridine
CID 158554525
N-(1-cyclopropylethyl)-2-(2-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-2-(2-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-4-methyl-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-(2-fluorophenyl)ethyl]-4-methyl-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-2-yl-N-[2,2,2-trifluoro-1-(4-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[2,2,2-trifluoro-1-(4-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158604275
(2R,3S)-4-[2-(6-cyclopropyl-7-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-3-methylpiperazine-2-carboxamide;4-[2-(6-cyclopropyl-7-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-3-methylpiperazine-2-carboxamide;(2-methoxy-4-pyridinyl)-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;3-[4-[4-(oxan-4-yl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
CID 158693104
2-(1,3-benzoxazol-7-yl)-N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(1,3-benzoxazol-7-yl)-N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-2-(6-cyclopropyloxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(2-oxo-3-propan-2-ylimidazolidin-1-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-methoxyphenyl)-4-methyl-N-[(2R)-1,1,1-trifluoropropan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158900408
N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenoxy)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyclopropyloxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-ethoxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-methoxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
CID 159313145

Frequently Asked Questions

What is the IUPAC name of N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide?
The IUPAC name of N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide (CID 157103535) is N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide.
What is the SMILES notation for N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide?
The canonical SMILES for N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide is Cc1cc(-c2cccc(F)c2)nc2c(C(=O)NC(C)(C)C)ncn12.Cc1cc(-c2ncc[nH]2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(Oc2cccc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2ccccn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2cccnc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(Oc2ccncc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.
What is the InChIKey of N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide?
The InChIKey is AGAPFVYIZCTMPG-WCFMXVFCSA-N. The full InChI is InChI=1S/C19H25F2N5O.C19H19FN4O2.C18H19FN4O.3C18H19N5O2.C17H20N6O/c1-12-10-14(25-8-6-19(20,21)7-9-25)23-16-15(22-11-26(12)16)17(27)24-18(2,3)13-4-5-13;1-11-8-16(26-15-5-3-4-14(20)9-15)23-18-17(21-10-24(11)18)19(25)22-12(2)13-6-7-13;1-11-8-14(12-6-5-7-13(19)9-12)21-16-15(20-10-23(11)16)17(24)22-18(2,3)4;1-11-9-15(25-14-5-7-19-8-6-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-3-4-13;1-11-8-15(25-14-4-3-7-19-9-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-5-6-13;1-11-9-15(25-14-5-3-4-8-19-14)22-17-16(20-10-23(11)17)18(24)21-12(2)13-6-7-13;1-10-8-12(14-18-6-7-19-14)21-15-13(20-9-23(10)15)16(24)22-17(2,3)11-4-5-11/h10-11,13H,4-9H2,1-3H3,(H,24,27);3-5,8-10,12-13H,6-7H2,1-2H3,(H,22,25);5-10H,1-4H3,(H,22,24);5-10,12-13H,3-4H2,1-2H3,(H,21,24);3-4,7-10,12-13H,5-6H2,1-2H3,(H,21,24);3-5,8-10,12-13H,6-7H2,1-2H3,(H,21,24);6-9,11H,4-5H2,1-3H3,(H,18,19)(H,22,24)/t;12-;;3*12-;/m.0.000./s1.
What are the key properties of N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide?
N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide has a molecular weight of 2394.74 g/mol, XLogP of 20.67, 30 rotatable bonds, 8 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 157103535), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).