N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

C126H121BrClF15N26O14 — CID 157120538

IUPACN-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cnc2c(C(=O)NC3(c4ccc(OC(F)F)c(F)c4)CCOCC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ncc(C(F)(F)F)cc4F)CCOCC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ncc(C(F)(F)F)cc2F)CCOCC1.O=C(NC1(c2ccc(Br)cc2)CCOCC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(Cl)c(F)c2)CCOCC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(OC(F)F)c(F)c2)CCOCC1)c1cnn2cc(C3CC3)cnc12
InChIInChI=1S/C22H21F4N5O2.C22H21F3N4O3.C21H21BrN4O2.C21H20ClFN4O2.C20H19F4N5O2.C20H19F3N4O3/c1-12-17(19-28-9-14(13-2-3-13)11-31(19)30-12)20(32)29-21(4-6-33-7-5-21)18-16(23)8-15(10-27-18)22(24,25)26;23-17-9-15(3-4-18(17)32-21(24)25)22(5-7-31-8-6-22)28-20(30)16-11-27-29-12-14(13-1-2-13)10-26-19(16)29;22-17-5-3-16(4-6-17)21(7-9-28-10-8-21)25-20(27)18-12-24-26-13-15(14-1-2-14)11-23-19(18)26;22-17-4-3-15(9-18(17)23)21(5-7-29-8-6-21)26-20(28)16-11-25-27-12-14(13-1-2-13)10-24-19(16)27;1-11-8-26-17-15(12(2)28-29(17)10-11)18(30)27-19(3-5-31-6-4-19)16-14(21)7-13(9-25-16)20(22,23)24;1-12-9-24-17-14(10-25-27(17)11-12)18(28)26-20(4-6-29-7-5-20)13-2-3-16(15(21)8-13)30-19(22)23/h8-11,13H,2-7H2,1H3,(H,29,32);3-4,9-13,21H,1-2,5-8H2,(H,28,30);3-6,11-14H,1-2,7-10H2,(H,25,27);3-4,9-13H,1-2,5-8H2,(H,26,28);7-10H,3-6H2,1-2H3,(H,27,30);2-3,8-11,19H,4-7H2,1H3,(H,26,28)
InChIKeyAHXLXUGAXDWCNB-UHFFFAOYSA-N
MW2623.85 g/mol
LogP21.88
Rot. Bonds26

About N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 157120538) has the molecular formula C126H121BrClF15N26O14 and a molecular weight of 2623.85 g/mol. Its IUPAC name is N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound NameN-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID157120538
Molecular FormulaC126H121BrClF15N26O14
Molecular Weight2623.85 g/mol
Exact Mass2620.82
IUPAC NameN-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cnc2c(C(=O)NC3(c4ccc(OC(F)F)c(F)c4)CCOCC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ncc(C(F)(F)F)cc4F)CCOCC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ncc(C(F)(F)F)cc2F)CCOCC1.O=C(NC1(c2ccc(Br)cc2)CCOCC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(Cl)c(F)c2)CCOCC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(OC(F)F)c(F)c2)CCOCC1)c1cnn2cc(C3CC3)cnc12
InChIInChI=1S/C22H21F4N5O2.C22H21F3N4O3.C21H21BrN4O2.C21H20ClFN4O2.C20H19F4N5O2.C20H19F3N4O3/c1-12-17(19-28-9-14(13-2-3-13)11-31(19)30-12)20(32)29-21(4-6-33-7-5-21)18-16(23)8-15(10-27-18)22(24,25)26;23-17-9-15(3-4-18(17)32-21(24)25)22(5-7-31-8-6-22)28-20(30)16-11-27-29-12-14(13-1-2-13)10-26-19(16)29;22-17-5-3-16(4-6-17)21(7-9-28-10-8-21)25-20(27)18-12-24-26-13-15(14-1-2-14)11-23-19(18)26;22-17-4-3-15(9-18(17)23)21(5-7-29-8-6-21)26-20(28)16-11-25-27-12-14(13-1-2-13)10-24-19(16)27;1-11-8-26-17-15(12(2)28-29(17)10-11)18(30)27-19(3-5-31-6-4-19)16-14(21)7-13(9-25-16)20(22,23)24;1-12-9-24-17-14(10-25-27(17)11-12)18(28)26-20(4-6-29-7-5-20)13-2-3-16(15(21)8-13)30-19(22)23/h8-11,13H,2-7H2,1H3,(H,29,32);3-4,9-13,21H,1-2,5-8H2,(H,28,30);3-6,11-14H,1-2,7-10H2,(H,25,27);3-4,9-13H,1-2,5-8H2,(H,26,28);7-10H,3-6H2,1-2H3,(H,27,30);2-3,8-11,19H,4-7H2,1H3,(H,26,28)
InChIKeyAHXLXUGAXDWCNB-UHFFFAOYSA-N
XLogP21.88
TPSA455.36 Ų
H-Bond Donors6
H-Bond Acceptors34
Rotatable Bonds26
Heavy Atoms183
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002623.85
LogP ≤ 521.88
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1034

Analyze N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethoxy)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157152189
N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-2-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-(4-quinolin-2-yloxan-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(trifluoromethyl)phenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(2-fluoro-3-methoxyphenyl)oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-(4-quinolin-2-yloxan-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[4-(trifluoromethyl)phenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157224875
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethoxy)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157687704
N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 159321021
N-[4-(2-chloro-4-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-2-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(trifluoromethyl)phenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(2-fluoro-3-methoxyphenyl)oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[4-(trifluoromethyl)phenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 159815352
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethoxy)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 160099746
N-[4-(4-chloro-2-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-(4-quinolin-2-yloxan-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(trifluoromethyl)phenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(2-fluoro-3-methoxyphenyl)oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-(4-quinolin-2-yloxan-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[4-(trifluoromethyl)phenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 160107418
CID 161509996
CID 161509996
N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 161856274
N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 162069465
7-butan-2-yl-3-(2-chloro-6-fluorophenyl)-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide;3-(2-chloro-6-fluoro-3-methoxyphenyl)-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-2-methyl-7-propan-2-ylpyrazolo[1,5-a]pyrimidine-6-carboxamide;3-(4-chloro-2-fluoro-3-methoxyphenyl)-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-2-methyl-7-propan-2-ylpyrazolo[1,5-a]pyrimidine-6-carboxamide;3-(2,6-difluoro-3-methoxyphenyl)-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-2-methyl-7-propan-2-ylpyrazolo[1,5-a]pyrimidine-6-carboxamide;N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-3-[2-fluoro-3-(trifluoromethoxy)phenyl]-2-methyl-7-propan-2-ylpyrazolo[1,5-a]pyrimidine-6-carboxamide
CID 162248168
N-[3-[5-bromo-2-(difluoromethoxy)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[5-chloro-2-(difluoromethoxy)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[5-cyclopropyl-2-(difluoromethoxy)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-(difluoromethoxy)-5-ethenylphenyl]-1-[2-(dimethylamino)-2-oxoethyl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157565625

Frequently Asked Questions

What is the IUPAC name of N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 157120538) is N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide is Cc1cnc2c(C(=O)NC3(c4ccc(OC(F)F)c(F)c4)CCOCC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ncc(C(F)(F)F)cc4F)CCOCC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ncc(C(F)(F)F)cc2F)CCOCC1.O=C(NC1(c2ccc(Br)cc2)CCOCC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(Cl)c(F)c2)CCOCC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(OC(F)F)c(F)c2)CCOCC1)c1cnn2cc(C3CC3)cnc12.
What is the InChIKey of N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is AHXLXUGAXDWCNB-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H21F4N5O2.C22H21F3N4O3.C21H21BrN4O2.C21H20ClFN4O2.C20H19F4N5O2.C20H19F3N4O3/c1-12-17(19-28-9-14(13-2-3-13)11-31(19)30-12)20(32)29-21(4-6-33-7-5-21)18-16(23)8-15(10-27-18)22(24,25)26;23-17-9-15(3-4-18(17)32-21(24)25)22(5-7-31-8-6-22)28-20(30)16-11-27-29-12-14(13-1-2-13)10-26-19(16)29;22-17-5-3-16(4-6-17)21(7-9-28-10-8-21)25-20(27)18-12-24-26-13-15(14-1-2-14)11-23-19(18)26;22-17-4-3-15(9-18(17)23)21(5-7-29-8-6-21)26-20(28)16-11-25-27-12-14(13-1-2-13)10-24-19(16)27;1-11-8-26-17-15(12(2)28-29(17)10-11)18(30)27-19(3-5-31-6-4-19)16-14(21)7-13(9-25-16)20(22,23)24;1-12-9-24-17-14(10-25-27(17)11-12)18(28)26-20(4-6-29-7-5-20)13-2-3-16(15(21)8-13)30-19(22)23/h8-11,13H,2-7H2,1H3,(H,29,32);3-4,9-13,21H,1-2,5-8H2,(H,28,30);3-6,11-14H,1-2,7-10H2,(H,25,27);3-4,9-13H,1-2,5-8H2,(H,26,28);7-10H,3-6H2,1-2H3,(H,27,30);2-3,8-11,19H,4-7H2,1H3,(H,26,28).
What are the key properties of N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2623.85 g/mol, XLogP of 21.88, 26 rotatable bonds, 6 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 157120538), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).