N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

C120H109Cl2F16N27O12 — CID 162069465

IUPACN-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cnc2c(C(=O)NC3(c4ccc(Cl)cc4F)CCOC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ncc(C(F)(F)F)cc4F)CCOC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ccc(C(F)(F)F)nc2)CCOC1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ncc(C(F)(F)F)cc2F)CCOC1.O=C(NC1(c2ccc(C(F)(F)F)cc2)CCOC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(Cl)cc2F)CCOC1)c1cnn2cc(C3CC3)cnc12
InChIInChI=1S/C21H19F4N5O2.C21H20F3N5O2.C21H19F3N4O2.C20H18ClFN4O2.C19H17F4N5O2.C18H16ClFN4O2/c1-11-16(18-27-7-13(12-2-3-12)9-30(18)29-11)19(31)28-20(4-5-32-10-20)17-15(22)6-14(8-26-17)21(23,24)25;1-12-17(18-26-8-14(13-2-3-13)10-29(18)28-12)19(30)27-20(6-7-31-11-20)15-4-5-16(25-9-15)21(22,23)24;22-21(23,24)16-5-3-15(4-6-16)20(7-8-30-12-20)27-19(29)17-10-26-28-11-14(13-1-2-13)9-25-18(17)28;21-14-3-4-16(17(22)7-14)20(5-6-28-11-20)25-19(27)15-9-24-26-10-13(12-1-2-12)8-23-18(15)26;1-10-6-25-16-14(11(2)27-28(16)8-10)17(29)26-18(3-4-30-9-18)15-13(20)5-12(7-24-15)19(21,22)23;1-11-7-21-16-13(8-22-24(16)9-11)17(25)23-18(4-5-26-10-18)14-3-2-12(19)6-15(14)20/h6-9,12H,2-5,10H2,1H3,(H,28,31);4-5,8-10,13H,2-3,6-7,11H2,1H3,(H,27,30);3-6,9-11,13H,1-2,7-8,12H2,(H,27,29);3-4,7-10,12H,1-2,5-6,11H2,(H,25,27);5-8H,3-4,9H2,1-2H3,(H,26,29);2-3,6-9H,4-5,10H2,1H3,(H,23,25)
InChIKeyZAWOOWRUNHRGJY-UHFFFAOYSA-N
MW2496.24 g/mol
LogP19.82
Rot. Bonds22

About N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 162069465) has the molecular formula C120H109Cl2F16N27O12 and a molecular weight of 2496.24 g/mol. Its IUPAC name is N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound NameN-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID162069465
Molecular FormulaC120H109Cl2F16N27O12
Molecular Weight2496.24 g/mol
Exact Mass2493.79
IUPAC NameN-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cnc2c(C(=O)NC3(c4ccc(Cl)cc4F)CCOC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ncc(C(F)(F)F)cc4F)CCOC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ccc(C(F)(F)F)nc2)CCOC1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ncc(C(F)(F)F)cc2F)CCOC1.O=C(NC1(c2ccc(C(F)(F)F)cc2)CCOC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(Cl)cc2F)CCOC1)c1cnn2cc(C3CC3)cnc12
InChIInChI=1S/C21H19F4N5O2.C21H20F3N5O2.C21H19F3N4O2.C20H18ClFN4O2.C19H17F4N5O2.C18H16ClFN4O2/c1-11-16(18-27-7-13(12-2-3-12)9-30(18)29-11)19(31)28-20(4-5-32-10-20)17-15(22)6-14(8-26-17)21(23,24)25;1-12-17(18-26-8-14(13-2-3-13)10-29(18)28-12)19(30)27-20(6-7-31-11-20)15-4-5-16(25-9-15)21(22,23)24;22-21(23,24)16-5-3-15(4-6-16)20(7-8-30-12-20)27-19(29)17-10-26-28-11-14(13-1-2-13)9-25-18(17)28;21-14-3-4-16(17(22)7-14)20(5-6-28-11-20)25-19(27)15-9-24-26-10-13(12-1-2-12)8-23-18(15)26;1-10-6-25-16-14(11(2)27-28(16)8-10)17(29)26-18(3-4-30-9-18)15-13(20)5-12(7-24-15)19(21,22)23;1-11-7-21-16-13(8-22-24(16)9-11)17(25)23-18(4-5-26-10-18)14-3-2-12(19)6-15(14)20/h6-9,12H,2-5,10H2,1H3,(H,28,31);4-5,8-10,13H,2-3,6-7,11H2,1H3,(H,27,30);3-6,9-11,13H,1-2,7-8,12H2,(H,27,29);3-4,7-10,12H,1-2,5-6,11H2,(H,25,27);5-8H,3-4,9H2,1-2H3,(H,26,29);2-3,6-9H,4-5,10H2,1H3,(H,23,25)
InChIKeyZAWOOWRUNHRGJY-UHFFFAOYSA-N
XLogP19.82
TPSA449.79 Ų
H-Bond Donors6
H-Bond Acceptors33
Rotatable Bonds22
Heavy Atoms177
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002496.24
LogP ≤ 519.82
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1033

Analyze N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

N-[4-(4-bromophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-(4-chloro-3-fluorophenyl)oxan-4-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[4-(difluoromethoxy)-3-fluorophenyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157120538
(3E)-3-[[5-[(3-chlorophenyl)methyl]-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]pyrrolidine-2,5-dione;(3E)-3-[[5-[(4-chlorophenyl)methyl]-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]pyrrolidine-2,5-dione;(3E)-3-[[7-(cyclopropylamino)-5-(dimethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]pyrrolidine-2,5-dione;(3E)-3-[[7-(cyclopropylamino)-5-ethylpyrazolo[1,5-a]pyrimidin-3-yl]methylidene]pyrrolidine-2,5-dione;(3E)-3-[[7-(cyclopropylamino)-5-(3-morpholin-4-yl-2-phenylpropyl)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]pyrrolidine-2,5-dione;(3E)-3-[[7-(cyclopropylamino)-5-[[3-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]pyrrolidine-2,5-dione
CID 157133660
N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethoxy)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157152189
6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157207969
6-cyclopropyl-N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxy-3-methyloxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxy-3-methyloxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157527128
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]-4-hydroxyoxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-3-hydroxy-3-methyloxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]-4-hydroxyoxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158064369
6-cyclopropyl-N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxy-3-methyloxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-3-hydroxyoxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxy-3-methyloxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158433336
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-fluoro-6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158445712
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158665724
1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2,5-dimethylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one;1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[[1-(2-hydroxyethyl)-3-methylpyrazol-4-yl]amino]pyrimidin-4-yl]pyridin-2-one;1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[[1-(2-hydroxyethyl)-5-methylpyrazol-4-yl]amino]pyrimidin-4-yl]pyridin-2-one;1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]pyridin-2-one;1-[(3-cyclopropyl-1H-indol-6-yl)methyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;1-[(6-fluoro-1H-indol-2-yl)methyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one
CID 158670830
6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158808370
2-(6-chloro-3-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-chloro-3-pyridinyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(2-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrazol-1-ylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide;bis(4-methyl-N-[2-(4-methylcyclohexyl)propan-2-yl]-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide)
CID 158859836

Frequently Asked Questions

What is the IUPAC name of N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 162069465) is N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide is Cc1cnc2c(C(=O)NC3(c4ccc(Cl)cc4F)CCOC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ncc(C(F)(F)F)cc4F)CCOC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ccc(C(F)(F)F)nc2)CCOC1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ncc(C(F)(F)F)cc2F)CCOC1.O=C(NC1(c2ccc(C(F)(F)F)cc2)CCOC1)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(Cl)cc2F)CCOC1)c1cnn2cc(C3CC3)cnc12.
What is the InChIKey of N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is ZAWOOWRUNHRGJY-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H19F4N5O2.C21H20F3N5O2.C21H19F3N4O2.C20H18ClFN4O2.C19H17F4N5O2.C18H16ClFN4O2/c1-11-16(18-27-7-13(12-2-3-12)9-30(18)29-11)19(31)28-20(4-5-32-10-20)17-15(22)6-14(8-26-17)21(23,24)25;1-12-17(18-26-8-14(13-2-3-13)10-29(18)28-12)19(30)27-20(6-7-31-11-20)15-4-5-16(25-9-15)21(22,23)24;22-21(23,24)16-5-3-15(4-6-16)20(7-8-30-12-20)27-19(29)17-10-26-28-11-14(13-1-2-13)9-25-18(17)28;21-14-3-4-16(17(22)7-14)20(5-6-28-11-20)25-19(27)15-9-24-26-10-13(12-1-2-12)8-23-18(15)26;1-10-6-25-16-14(11(2)27-28(16)8-10)17(29)26-18(3-4-30-9-18)15-13(20)5-12(7-24-15)19(21,22)23;1-11-7-21-16-13(8-22-24(16)9-11)17(25)23-18(4-5-26-10-18)14-3-2-12(19)6-15(14)20/h6-9,12H,2-5,10H2,1H3,(H,28,31);4-5,8-10,13H,2-3,6-7,11H2,1H3,(H,27,30);3-6,9-11,13H,1-2,7-8,12H2,(H,27,29);3-4,7-10,12H,1-2,5-6,11H2,(H,25,27);5-8H,3-4,9H2,1-2H3,(H,26,29);2-3,6-9H,4-5,10H2,1H3,(H,23,25).
What are the key properties of N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2496.24 g/mol, XLogP of 19.82, 22 rotatable bonds, 6 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-chloro-2-fluorophenyl)oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-[4-(trifluoromethyl)phenyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 162069465), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).