bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

C164H242FN23O14S3 — CID 157177277

About bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 157177277) has the molecular formula C164H242FN23O14S3 and a molecular weight of 2875.09 g/mol. Its IUPAC name is bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

• Compound Name: bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
• PubChem CID: 157177277
• Molecular Formula: C164H242FN23O14S3
• Molecular Weight: 2875.09 g/mol
• Exact Mass: 2872.81
• IUPAC Name: bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
• SMILES: CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(CCS(C)(=O)=O)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(c3cccnc3)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(c3ccncc3)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)N1CCCC1=O)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)S(C)(=O)=O)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)S(C)(=O)=O)C(=O)N2CC1CCC1
• InChI: InChI=1S/2C30H41N5O.C29H44N4O3.2C26H41N3O3S.C23H34FN3O3S/c1-32(2)30(25-7-4-3-5-8-25)16-14-29(15-17-30)23-34(28(36)35(29)22-24-10-11-24)26-12-19-33(20-13-26)27-9-6-18-31-21-27;1-32(2)30(25-6-4-3-5-7-25)16-14-29(15-17-30)23-34(28(36)35(29)22-24-8-9-24)27-12-20-33(21-13-27)26-10-18-31-19-11-26;1-26(2,32-19-8-12-24(32)34)20-31-21-27(33(25(31)35)22-28(36)13-9-14-28)15-17-29(18-16-27,30(3)4)23-10-6-5-7-11-23;2*1-24(2,33(5,31)32)19-28-20-25(29(23(28)30)18-21-10-9-11-21)14-16-26(17-15-25,27(3)4)22-12-7-6-8-13-22;1-25(2)23(19-5-4-6-20(24)15-19)11-9-22(10-12-23)17-26(13-14-31(3,29)30)21(28)27(22)16-18-7-8-18/h3-9,18,21,24,26H,10-17,19-20,22-23H2,1-2H3;3-7,10-11,18-19,24,27H,8-9,12-17,20-23H2,1-2H3;5-7,10-11,36H,8-9,12-22H2,1-4H3;2*6-8,12-13,21H,9-11,14-20H2,1-5H3;4-6,15,18H,7-14,16-17H2,1-3H3
• InChIKey: AODUSQVLJQKDJZ-UHFFFAOYSA-N
• XLogP: 25.07
• TPSA: 335.96 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 24
• Rotatable Bonds: 40
• Heavy Atoms: 205
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2875.09
LogP ≤ 5	25.07
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	24

Frequently Asked Questions

What is the IUPAC name of bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?

The IUPAC name of bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (CID 157177277) is bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.

What is the SMILES notation for bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?

The canonical SMILES for bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(CCS(C)(=O)=O)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(c3cccnc3)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(c3ccncc3)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)N1CCCC1=O)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)S(C)(=O)=O)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)S(C)(=O)=O)C(=O)N2CC1CCC1.

What is the InChIKey of bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?

The InChIKey is AODUSQVLJQKDJZ-UHFFFAOYSA-N. The full InChI is InChI=1S/2C30H41N5O.C29H44N4O3.2C26H41N3O3S.C23H34FN3O3S/c1-32(2)30(25-7-4-3-5-8-25)16-14-29(15-17-30)23-34(28(36)35(29)22-24-10-11-24)26-12-19-33(20-13-26)27-9-6-18-31-21-27;1-32(2)30(25-6-4-3-5-7-25)16-14-29(15-17-30)23-34(28(36)35(29)22-24-8-9-24)27-12-20-33(21-13-27)26-10-18-31-19-11-26;1-26(2,32-19-8-12-24(32)34)20-31-21-27(33(25(31)35)22-28(36)13-9-14-28)15-17-29(18-16-27,30(3)4)23-10-6-5-7-11-23;2*1-24(2,33(5,31)32)19-28-20-25(29(23(28)30)18-21-10-9-11-21)14-16-26(17-15-25,27(3)4)22-12-7-6-8-13-22;1-25(2)23(19-5-4-6-20(24)15-19)11-9-22(10-12-23)17-26(13-14-31(3,29)30)21(28)27(22)16-18-7-8-18/h3-9,18,21,24,26H,10-17,19-20,22-23H2,1-2H3;3-7,10-11,18-19,24,27H,8-9,12-17,20-23H2,1-2H3;5-7,10-11,36H,8-9,12-22H2,1-4H3;2*6-8,12-13,21H,9-11,14-20H2,1-5H3;4-6,15,18H,7-14,16-17H2,1-3H3.

What are the key properties of bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?

bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 2875.09 g/mol, XLogP of 25.07, 40 rotatable bonds, 1 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 157177277), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).