3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one

C153H219N23O14S — CID 160965837

IUPAC3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one
SMILESCC(=O)N1CCC(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(C(=O)c3ccccc3)CC1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(C(=O)c3ccncc3)CC1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)O)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC1(N)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC1(O)CCS(=O)(=O)CC1)C(=O)N2CC1CC1
InChIInChI=1S/C28H36N4O2.C27H35N5O2.C26H39N3O4S.C25H39N3O3.C24H36N4O.C23H34N4O2/c1-30(2)28(23-11-7-4-8-12-23)17-15-27(16-18-28)21-32(26(34)29-27)24-13-19-31(20-14-24)25(33)22-9-5-3-6-10-22;1-30(2)27(22-6-4-3-5-7-22)14-12-26(13-15-27)20-32(25(34)29-26)23-10-18-31(19-11-23)24(33)21-8-16-28-17-9-21;1-27(2)26(22-6-4-3-5-7-22)12-10-24(11-13-26)19-28(23(30)29(24)18-21-8-9-21)20-25(31)14-16-34(32,33)17-15-25;1-22(2,30)17-27-18-23(28(21(27)29)19-24(31)11-8-12-24)13-15-25(16-14-23,26(3)4)20-9-6-5-7-10-20;1-26(2)24(20-6-4-3-5-7-20)14-12-23(13-15-24)18-27(17-22(25)10-11-22)21(29)28(23)16-19-8-9-19;1-18(28)26-15-9-20(10-16-26)27-17-22(24-21(27)29)11-13-23(14-12-22,25(2)3)19-7-5-4-6-8-19/h3-12,24H,13-21H2,1-2H3,(H,29,34);3-9,16-17,23H,10-15,18-20H2,1-2H3,(H,29,34);3-7,21,31H,8-20H2,1-2H3;5-7,9-10,30-31H,8,11-19H2,1-4H3;3-7,19H,8-18,25H2,1-2H3;4-8,20H,9-17H2,1-3H3,(H,24,29)
InChIKeySXPMANQBFXHKJN-UHFFFAOYSA-N
MW2636.65 g/mol
LogP19.78
Rot. Bonds29

About 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one

3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 160965837) has the molecular formula C153H219N23O14S and a molecular weight of 2636.65 g/mol. Its IUPAC name is 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Name3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one
PubChem CID160965837
Molecular FormulaC153H219N23O14S
Molecular Weight2636.65 g/mol
Exact Mass2634.69
IUPAC Name3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one
SMILESCC(=O)N1CCC(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(C(=O)c3ccccc3)CC1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(C(=O)c3ccncc3)CC1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)O)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC1(N)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC1(O)CCS(=O)(=O)CC1)C(=O)N2CC1CC1
InChIInChI=1S/C28H36N4O2.C27H35N5O2.C26H39N3O4S.C25H39N3O3.C24H36N4O.C23H34N4O2/c1-30(2)28(23-11-7-4-8-12-23)17-15-27(16-18-28)21-32(26(34)29-27)24-13-19-31(20-14-24)25(33)22-9-5-3-6-10-22;1-30(2)27(22-6-4-3-5-7-22)14-12-26(13-15-27)20-32(25(34)29-26)23-10-18-31(19-11-23)24(33)21-8-16-28-17-9-21;1-27(2)26(22-6-4-3-5-7-22)12-10-24(11-13-26)19-28(23(30)29(24)18-21-8-9-21)20-25(31)14-16-34(32,33)17-15-25;1-22(2,30)17-27-18-23(28(21(27)29)19-24(31)11-8-12-24)13-15-25(16-14-23,26(3)4)20-9-6-5-7-10-20;1-26(2)24(20-6-4-3-5-7-20)14-12-23(13-15-24)18-27(17-22(25)10-11-22)21(29)28(23)16-19-8-9-19;1-18(28)26-15-9-20(10-16-26)27-17-22(24-21(27)29)11-13-23(14-12-22,25(2)3)19-7-5-4-6-8-19/h3-12,24H,13-21H2,1-2H3,(H,29,34);3-9,16-17,23H,10-15,18-20H2,1-2H3,(H,29,34);3-7,21,31H,8-20H2,1-2H3;5-7,9-10,30-31H,8,11-19H2,1-4H3;3-7,19H,8-18,25H2,1-2H3;4-8,20H,9-17H2,1-3H3,(H,24,29)
InChIKeySXPMANQBFXHKJN-UHFFFAOYSA-N
XLogP19.78
TPSA381.78 Ų
H-Bond Donors7
H-Bond Acceptors22
Rotatable Bonds29
Heavy Atoms191
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002636.65
LogP ≤ 519.78
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1022

Analyze 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one with MolForge

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Related Compounds

Bis(1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
CID 157177277
CID 158417322
CID 158417322
3-(1-Acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1,3-bis(2-methylsulfonylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one
CID 158817299
3-(1-Acetylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(1,1-dioxothian-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1,1-dioxothian-4-yl)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
CID 159555255
3-(1-Acetylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxyoxan-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one
CID 159845028
3-(1-Acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-phenylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(piperidin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one
CID 160167596
3-(1-Acetylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxyoxan-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1,1-dioxothian-4-yl)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
CID 160250828
1-(Cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;bis(3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(ethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one);3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide
CID 160839521
3-[(1-Acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxyoxan-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one
CID 160916082
3-(1-Acetylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1,1-dioxothian-4-yl)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
CID 160943228
1-(Cyclobutylmethyl)-8-(dimethylamino)-3-(2-methyl-2-methylsulfonylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-[2-methyl-2-(2-oxopyrrolidin-1-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
CID 160992630
1-(Cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-(2-methylsulfonylethyl)-1,3-diazaspiro[4.5]decan-2-one;1-[1-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-methylpropan-2-yl]pyrrolidine-2,5-dione;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-3-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyridin-4-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2,2-dimethyl-3-methylsulfonylpropyl)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2,2-dimethyl-4-oxopentyl)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
CID 161604873

Frequently Asked Questions

What is the IUPAC name of 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one (CID 160965837) is 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one is CC(=O)N1CCC(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(C(=O)c3ccccc3)CC1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(C(=O)c3ccncc3)CC1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)O)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC1(N)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC1(O)CCS(=O)(=O)CC1)C(=O)N2CC1CC1.
What is the InChIKey of 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is SXPMANQBFXHKJN-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H36N4O2.C27H35N5O2.C26H39N3O4S.C25H39N3O3.C24H36N4O.C23H34N4O2/c1-30(2)28(23-11-7-4-8-12-23)17-15-27(16-18-28)21-32(26(34)29-27)24-13-19-31(20-14-24)25(33)22-9-5-3-6-10-22;1-30(2)27(22-6-4-3-5-7-22)14-12-26(13-15-27)20-32(25(34)29-26)23-10-18-31(19-11-23)24(33)21-8-16-28-17-9-21;1-27(2)26(22-6-4-3-5-7-22)12-10-24(11-13-26)19-28(23(30)29(24)18-21-8-9-21)20-25(31)14-16-34(32,33)17-15-25;1-22(2,30)17-27-18-23(28(21(27)29)19-24(31)11-8-12-24)13-15-25(16-14-23,26(3)4)20-9-6-5-7-10-20;1-26(2)24(20-6-4-3-5-7-20)14-12-23(13-15-24)18-27(17-22(25)10-11-22)21(29)28(23)16-19-8-9-19;1-18(28)26-15-9-20(10-16-26)27-17-22(24-21(27)29)11-13-23(14-12-22,25(2)3)19-7-5-4-6-8-19/h3-12,24H,13-21H2,1-2H3,(H,29,34);3-9,16-17,23H,10-15,18-20H2,1-2H3,(H,29,34);3-7,21,31H,8-20H2,1-2H3;5-7,9-10,30-31H,8,11-19H2,1-4H3;3-7,19H,8-18,25H2,1-2H3;4-8,20H,9-17H2,1-3H3,(H,24,29).
What are the key properties of 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one?
3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 2636.65 g/mol, XLogP of 19.78, 29 rotatable bonds, 7 hydrogen bond donors, and 22 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(1-acetylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[(1-aminocyclopropyl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(1-benzoylpiperidin-4-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-[(4-hydroxy-1,1-dioxothian-4-yl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 160965837), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).