1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one

C107H129Cl5F9N5O12 — CID 157189862

IUPAC1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one
SMILESCC1CC(CCC(=O)c2cc(CCO)n3cccc(Cl)c23)CCC1(F)F.COCCc1cc(C(=O)CCC2(O)CCCC3(CC3)C2)c2c(Cl)cccn12.COCCc1cc(C(=O)CCC2CCCC(F)(F)C2)c2c(Cl)cccn12.O=C(CCC1(O)CCCC(C(F)(F)F)C1)c1cc(C2CCOCC2)n2cccc(Cl)c12.O=C(CCC1CCC(F)(F)CC1)c1cc(CC2CCOC2)n2cccc(Cl)c12
InChIInChI=1S/C23H27ClF3NO3.C22H26ClF2NO2.C22H28ClNO3.2C20H24ClF2NO2/c24-18-4-2-10-28-19(15-6-11-31-12-7-15)13-17(21(18)28)20(29)5-9-22(30)8-1-3-16(14-22)23(25,26)27;23-19-2-1-10-26-17(12-16-7-11-28-14-16)13-18(21(19)26)20(27)4-3-15-5-8-22(24,25)9-6-15;1-27-13-6-16-14-17(20-18(23)4-2-12-24(16)20)19(25)5-9-22(26)8-3-7-21(15-22)10-11-21;1-26-11-8-15-12-16(19-17(21)5-3-10-24(15)19)18(25)7-6-14-4-2-9-20(22,23)13-14;1-13-11-14(6-8-20(13,22)23)4-5-18(26)16-12-15(7-10-25)24-9-2-3-17(21)19(16)24/h2,4,10,13,15-16,30H,1,3,5-9,11-12,14H2;1-2,10,13,15-16H,3-9,11-12,14H2;2,4,12,14,26H,3,5-11,13,15H2,1H3;3,5,10,12,14H,2,4,6-9,11,13H2,1H3;2-3,9,12-14,25H,4-8,10-11H2,1H3
InChIKeyAPOPBVWVTLIEHK-UHFFFAOYSA-N
MW2025.48 g/mol
LogP27.45
Rot. Bonds31

About 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one

1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one (PubChem CID 157189862) has the molecular formula C107H129Cl5F9N5O12 and a molecular weight of 2025.48 g/mol. Its IUPAC name is 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one.

Molecular Properties

Compound Name1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one
PubChem CID157189862
Molecular FormulaC107H129Cl5F9N5O12
Molecular Weight2025.48 g/mol
Exact Mass2021.79
IUPAC Name1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one
SMILESCC1CC(CCC(=O)c2cc(CCO)n3cccc(Cl)c23)CCC1(F)F.COCCc1cc(C(=O)CCC2(O)CCCC3(CC3)C2)c2c(Cl)cccn12.COCCc1cc(C(=O)CCC2CCCC(F)(F)C2)c2c(Cl)cccn12.O=C(CCC1(O)CCCC(C(F)(F)F)C1)c1cc(C2CCOCC2)n2cccc(Cl)c12.O=C(CCC1CCC(F)(F)CC1)c1cc(CC2CCOC2)n2cccc(Cl)c12
InChIInChI=1S/C23H27ClF3NO3.C22H26ClF2NO2.C22H28ClNO3.2C20H24ClF2NO2/c24-18-4-2-10-28-19(15-6-11-31-12-7-15)13-17(21(18)28)20(29)5-9-22(30)8-1-3-16(14-22)23(25,26)27;23-19-2-1-10-26-17(12-16-7-11-28-14-16)13-18(21(19)26)20(27)4-3-15-5-8-22(24,25)9-6-15;1-27-13-6-16-14-17(20-18(23)4-2-12-24(16)20)19(25)5-9-22(26)8-3-7-21(15-22)10-11-21;1-26-11-8-15-12-16(19-17(21)5-3-10-24(15)19)18(25)7-6-14-4-2-9-20(22,23)13-14;1-13-11-14(6-8-20(13,22)23)4-5-18(26)16-12-15(7-10-25)24-9-2-3-17(21)19(16)24/h2,4,10,13,15-16,30H,1,3,5-9,11-12,14H2;1-2,10,13,15-16H,3-9,11-12,14H2;2,4,12,14,26H,3,5-11,13,15H2,1H3;3,5,10,12,14H,2,4,6-9,11,13H2,1H3;2-3,9,12-14,25H,4-8,10-11H2,1H3
InChIKeyAPOPBVWVTLIEHK-UHFFFAOYSA-N
XLogP27.45
TPSA205.01 Ų
H-Bond Donors3
H-Bond Acceptors17
Rotatable Bonds31
Heavy Atoms138
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002025.48
LogP ≤ 527.45
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1017

Analyze 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one with MolForge

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Related Compounds

8-chloro-N-[(4,4-difluorocyclohexyl)methyl]indolizine-1-carboxamide;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-(4,4-difluoro-1-hydroxy-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-[(1S,3R)-1-hydroxy-3-methylcyclohexyl]propan-1-one
CID 157081558
8-chloro-N-[(4,4-difluorocyclohexyl)methyl]indolizine-1-carboxamide;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(4,4-difluoro-1-hydroxy-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-(4,4-difluoro-1-hydroxy-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-(4,4-difluoro-1-hydroxy-3-methylcyclohexyl)propan-1-one
CID 157287360
1-(8-chloro-3-cyclobutylindolizin-1-yl)-3-(3,3-difluoro-1-hydroxycyclohexyl)propan-1-one;1-[8-chloro-3-(2-ethoxyethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-[(1S,3R)-1-hydroxy-3-methylcyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-2-yl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one
CID 157479499
1-[8-chloro-3-(2-fluoroethyl)indolizin-1-yl]-3-(3,3-difluoro-1-hydroxycyclohexyl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-(1-hydroxy-3-methylcyclohexyl)propan-1-one;1-(8-chloro-3-phenylindolizin-1-yl)-3-(1-hydroxy-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-[2-(trideuteriomethoxy)ethyl]indolizin-1-yl]-3-[(1R)-1-hydroxy-3-methylcyclohexyl]propan-1-one;1-[8-chloro-3-[2-(trideuteriomethoxy)ethyl]indolizin-1-yl]-3-[(1S)-1-hydroxy-3-methylcyclohexyl]propan-1-one
CID 157699242
1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(3,3-difluoro-1-hydroxycyclohexyl)propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-[(1R)-3,3-difluoro-1-hydroxycyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-[(1S)-3,3-difluoro-1-hydroxycyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-(3,3-difluoro-1-hydroxycyclohexyl)propan-1-one
CID 157854598
1-[8-Chloro-3-(2-fluoroethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(3,3-difluoro-5-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(1-hydroxycycloheptyl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one
CID 158130580
8-chloro-N-[(4,4-difluorocyclohexyl)methyl]-3-(3-hydroxyoxetan-3-yl)indolizine-1-carboxamide;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluoro-1-hydroxycyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-4-(1-hydroxycyclopentyl)butan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-(4,4-difluoro-1-hydroxycyclohexyl)propan-1-one;3-(3,3-difluoro-1-hydroxycyclohexyl)-1-[3-(2-methoxyethyl)-8-(trifluoromethyl)indolizin-1-yl]propan-1-one
CID 158268964
1-[8-chloro-3-(2-ethoxyethyl)indolizin-1-yl]-3-(1-hydroxy-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-ethoxyethyl)indolizin-1-yl]-3-[(1S,3R)-1-hydroxy-3-methylcyclohexyl]propan-1-one;1-[8-chloro-3-(1-hydroxypropan-2-yl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one
CID 158333726
1-[8-Chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one
CID 158368235
1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-[(1R)-3,3-difluoro-1-hydroxycyclohexyl]propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-[(1S)-3,3-difluoro-1-hydroxycyclohexyl]propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluoro-1-hydroxycyclohexyl)propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-[(1S)-3,3-difluoro-1-hydroxycyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-yl)indolizin-1-yl]-3-(3,3-difluoro-1-hydroxycyclohexyl)propan-1-one
CID 158439027
1-[8-chloro-3-(2,3-dihydrofuran-4-yl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-cyclohexylpropan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-[(1S,3R)-1-hydroxy-3-methylcyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-2-yl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;3-[(1S,3R)-1-hydroxy-3-methylcyclohexyl]-1-[3-(2-methoxyethyl)-8-methylindolizin-1-yl]propan-1-one
CID 158614809
1-[8-chloro-3-(2,3-dihydrofuran-4-yl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-cyclohexylpropan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluoro-5-methylcyclohexyl)propan-1-one;3-[(1S)-1-hydroxy-3-methylcyclohexyl]-1-[3-(2-methoxyethyl)-8-methylindolizin-1-yl]propan-1-one
CID 158773493

Frequently Asked Questions

What is the IUPAC name of 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one?
The IUPAC name of 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one (CID 157189862) is 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one.
What is the SMILES notation for 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one?
The canonical SMILES for 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one is CC1CC(CCC(=O)c2cc(CCO)n3cccc(Cl)c23)CCC1(F)F.COCCc1cc(C(=O)CCC2(O)CCCC3(CC3)C2)c2c(Cl)cccn12.COCCc1cc(C(=O)CCC2CCCC(F)(F)C2)c2c(Cl)cccn12.O=C(CCC1(O)CCCC(C(F)(F)F)C1)c1cc(C2CCOCC2)n2cccc(Cl)c12.O=C(CCC1CCC(F)(F)CC1)c1cc(CC2CCOC2)n2cccc(Cl)c12.
What is the InChIKey of 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one?
The InChIKey is APOPBVWVTLIEHK-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H27ClF3NO3.C22H26ClF2NO2.C22H28ClNO3.2C20H24ClF2NO2/c24-18-4-2-10-28-19(15-6-11-31-12-7-15)13-17(21(18)28)20(29)5-9-22(30)8-1-3-16(14-22)23(25,26)27;23-19-2-1-10-26-17(12-16-7-11-28-14-16)13-18(21(19)26)20(27)4-3-15-5-8-22(24,25)9-6-15;1-27-13-6-16-14-17(20-18(23)4-2-12-24(16)20)19(25)5-9-22(26)8-3-7-21(15-22)10-11-21;1-26-11-8-15-12-16(19-17(21)5-3-10-24(15)19)18(25)7-6-14-4-2-9-20(22,23)13-14;1-13-11-14(6-8-20(13,22)23)4-5-18(26)16-12-15(7-10-25)24-9-2-3-17(21)19(16)24/h2,4,10,13,15-16,30H,1,3,5-9,11-12,14H2;1-2,10,13,15-16H,3-9,11-12,14H2;2,4,12,14,26H,3,5-11,13,15H2,1H3;3,5,10,12,14H,2,4,6-9,11,13H2,1H3;2-3,9,12-14,25H,4-8,10-11H2,1H3.
What are the key properties of 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one?
1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one has a molecular weight of 2025.48 g/mol, XLogP of 27.45, 31 rotatable bonds, 3 hydrogen bond donors, and 17 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[8-chloro-3-(2-hydroxyethyl)indolizin-1-yl]-3-(4,4-difluoro-3-methylcyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(3,3-difluorocyclohexyl)propan-1-one;1-[8-chloro-3-(2-methoxyethyl)indolizin-1-yl]-3-(7-hydroxyspiro[2.5]octan-7-yl)propan-1-one;1-[8-chloro-3-(oxan-4-yl)indolizin-1-yl]-3-[1-hydroxy-3-(trifluoromethyl)cyclohexyl]propan-1-one;1-[8-chloro-3-(oxolan-3-ylmethyl)indolizin-1-yl]-3-(4,4-difluorocyclohexyl)propan-1-one is sourced from PubChem (CID 157189862), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).