6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one

C169H154Cl5N27O13S — CID 157203590

About 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one

6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one (PubChem CID 157203590) has the molecular formula C169H154Cl5N27O13S and a molecular weight of 2980.60 g/mol. Its IUPAC name is 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 157203590
• Molecular Formula: C169H154Cl5N27O13S
• Molecular Weight: 2980.60 g/mol
• Exact Mass: 2976.04
• IUPAC Name: 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one
• SMILES: Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3C(=O)c4ccccc4NC3(C)C)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3C(=O)c4ccccc4OC3(C)C)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3COc4ccccc4C3)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3CSc4ccccc4C3)c2=O)c(Cl)c1.O=c1c(-c2ccccc2Cl)cc2cnc(Nc3ccc(C4=CCNCC4)cc3)nc2n1C1CNc2ccccc2C1
• InChI: InChI=1S/C35H33ClN6O3.C35H32ClN5O4.C33H29ClN6O.C33H30ClN5O3.C33H30ClN5O2S/c1-20-8-13-24(27(36)16-20)26-17-22-18-38-34(39-23-11-9-21(10-12-23)29-19-37-14-15-45-29)40-32(22)42(33(26)44)31-30(43)25-6-4-5-7-28(25)41-35(31,2)3;1-20-8-13-24(27(36)16-20)26-17-22-18-38-34(39-23-11-9-21(10-12-23)29-19-37-14-15-44-29)40-32(22)41(33(26)43)31-30(42)25-6-4-5-7-28(25)45-35(31,2)3;34-29-7-3-2-6-27(29)28-18-24-19-37-33(38-25-11-9-21(10-12-25)22-13-15-35-16-14-22)39-31(24)40(32(28)41)26-17-23-5-1-4-8-30(23)36-20-26;1-20-6-11-26(28(34)14-20)27-16-23-17-36-33(37-24-9-7-21(8-10-24)30-18-35-12-13-41-30)38-31(23)39(32(27)40)25-15-22-4-2-3-5-29(22)42-19-25;1-20-6-11-26(28(34)14-20)27-16-23-17-36-33(37-24-9-7-21(8-10-24)29-18-35-12-13-41-29)38-31(23)39(32(27)40)25-15-22-4-2-3-5-30(22)42-19-25/h4-13,16-18,29,31,37,41H,14-15,19H2,1-3H3,(H,38,39,40);4-13,16-18,29,31,37H,14-15,19H2,1-3H3,(H,38,39,40);1-13,18-19,26,35-36H,14-17,20H2,(H,37,38,39);2-11,14,16-17,25,30,35H,12-13,15,18-19H2,1H3,(H,36,37,38);2-11,14,16-17,25,29,35H,12-13,15,18-19H2,1H3,(H,36,37,38)
• InChIKey: ARBWYDNPHRWPDJ-UHFFFAOYSA-N
• XLogP: 32.03
• TPSA: 472.78 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 41
• Rotatable Bonds: 25
• Heavy Atoms: 215
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2980.60
LogP ≤ 5	32.03
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	41

Frequently Asked Questions

What is the IUPAC name of 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one (CID 157203590) is 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one is Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3C(=O)c4ccccc4NC3(C)C)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3C(=O)c4ccccc4OC3(C)C)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3COc4ccccc4C3)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3CSc4ccccc4C3)c2=O)c(Cl)c1.O=c1c(-c2ccccc2Cl)cc2cnc(Nc3ccc(C4=CCNCC4)cc3)nc2n1C1CNc2ccccc2C1.

What is the InChIKey of 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is ARBWYDNPHRWPDJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C35H33ClN6O3.C35H32ClN5O4.C33H29ClN6O.C33H30ClN5O3.C33H30ClN5O2S/c1-20-8-13-24(27(36)16-20)26-17-22-18-38-34(39-23-11-9-21(10-12-23)29-19-37-14-15-45-29)40-32(22)42(33(26)44)31-30(43)25-6-4-5-7-28(25)41-35(31,2)3;1-20-8-13-24(27(36)16-20)26-17-22-18-38-34(39-23-11-9-21(10-12-23)29-19-37-14-15-44-29)40-32(22)41(33(26)43)31-30(42)25-6-4-5-7-28(25)45-35(31,2)3;34-29-7-3-2-6-27(29)28-18-24-19-37-33(38-25-11-9-21(10-12-25)22-13-15-35-16-14-22)39-31(24)40(32(28)41)26-17-23-5-1-4-8-30(23)36-20-26;1-20-6-11-26(28(34)14-20)27-16-23-17-36-33(37-24-9-7-21(8-10-24)30-18-35-12-13-41-30)38-31(23)39(32(27)40)25-15-22-4-2-3-5-29(22)42-19-25;1-20-6-11-26(28(34)14-20)27-16-23-17-36-33(37-24-9-7-21(8-10-24)29-18-35-12-13-41-29)38-31(23)39(32(27)40)25-15-22-4-2-3-5-30(22)42-19-25/h4-13,16-18,29,31,37,41H,14-15,19H2,1-3H3,(H,38,39,40);4-13,16-18,29,31,37H,14-15,19H2,1-3H3,(H,38,39,40);1-13,18-19,26,35-36H,14-17,20H2,(H,37,38,39);2-11,14,16-17,25,30,35H,12-13,15,18-19H2,1H3,(H,36,37,38);2-11,14,16-17,25,29,35H,12-13,15,18-19H2,1H3,(H,36,37,38).

What are the key properties of 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one?

6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 2980.60 g/mol, XLogP of 32.03, 25 rotatable bonds, 12 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-3H-chromen-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 157203590), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).