6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one

C133H123Cl4F2N25O7S — CID 157405939

About 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one

6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one (PubChem CID 157405939) has the molecular formula C133H123Cl4F2N25O7S and a molecular weight of 2395.49 g/mol. Its IUPAC name is 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 157405939
• Molecular Formula: C133H123Cl4F2N25O7S
• Molecular Weight: 2395.49 g/mol
• Exact Mass: 2391.85
• IUPAC Name: 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one
• SMILES: CC1(C)Nc2ccccc2C(=O)C1n1c(=O)c(-c2ccccc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)c(F)c3)nc21.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3CNc4ccccc4C3)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3Cc4ccccc4N(C)C3)c2=O)c(Cl)c1.O=c1c(-c2ccccc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)c(F)c3)nc2n1C1CSc2ccccc2C1
• InChI: InChI=1S/C34H31ClFN7O2.C34H33ClN6O2.C33H31ClN6O2.C32H28ClFN6OS/c1-34(2)30(29(44)23-8-4-6-10-27(23)41-34)43-31-20(17-24(32(43)45)22-7-3-5-9-25(22)35)19-38-33(40-31)39-21-11-12-28(26(36)18-21)42-15-13-37-14-16-42;1-21-7-12-27(29(35)15-21)28-17-24-18-37-34(38-25-10-8-22(9-11-25)31-19-36-13-14-43-31)39-32(24)41(33(28)42)26-16-23-5-3-4-6-30(23)40(2)20-26;1-20-6-11-26(28(34)14-20)27-16-23-17-37-33(38-24-9-7-21(8-10-24)30-19-35-12-13-42-30)39-31(23)40(32(27)41)25-15-22-4-2-3-5-29(22)36-18-25;33-26-7-3-2-6-24(26)25-16-21-18-36-32(37-22-9-10-28(27(34)17-22)39-13-11-35-12-14-39)38-30(21)40(31(25)41)23-15-20-5-1-4-8-29(20)42-19-23/h3-12,17-19,30,37,41H,13-16H2,1-2H3,(H,38,39,40);3-12,15,17-18,26,31,36H,13-14,16,19-20H2,1-2H3,(H,37,38,39);2-11,14,16-17,25,30,35-36H,12-13,15,18-19H2,1H3,(H,37,38,39);1-10,16-18,23,35H,11-15,19H2,(H,36,37,38)
• InChIKey: BNSGIAIOSIEKEV-UHFFFAOYSA-N
• XLogP: 24.42
• TPSA: 356.67 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 33
• Rotatable Bonds: 20
• Heavy Atoms: 172
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2395.49
LogP ≤ 5	24.42
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	33

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one (CID 157405939) is 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one is CC1(C)Nc2ccccc2C(=O)C1n1c(=O)c(-c2ccccc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)c(F)c3)nc21.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3CNc4ccccc4C3)c2=O)c(Cl)c1.Cc1ccc(-c2cc3cnc(Nc4ccc(C5CNCCO5)cc4)nc3n(C3Cc4ccccc4N(C)C3)c2=O)c(Cl)c1.O=c1c(-c2ccccc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)c(F)c3)nc2n1C1CSc2ccccc2C1.

What is the InChIKey of 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is BNSGIAIOSIEKEV-UHFFFAOYSA-N. The full InChI is InChI=1S/C34H31ClFN7O2.C34H33ClN6O2.C33H31ClN6O2.C32H28ClFN6OS/c1-34(2)30(29(44)23-8-4-6-10-27(23)41-34)43-31-20(17-24(32(43)45)22-7-3-5-9-25(22)35)19-38-33(40-31)39-21-11-12-28(26(36)18-21)42-15-13-37-14-16-42;1-21-7-12-27(29(35)15-21)28-17-24-18-37-34(38-25-10-8-22(9-11-25)31-19-36-13-14-43-31)39-32(24)41(33(28)42)26-16-23-5-3-4-6-30(23)40(2)20-26;1-20-6-11-26(28(34)14-20)27-16-23-17-37-33(38-24-9-7-21(8-10-24)30-19-35-12-13-42-30)39-31(23)40(32(27)41)25-15-22-4-2-3-5-29(22)36-18-25;33-26-7-3-2-6-24(26)25-16-21-18-36-32(37-22-9-10-28(27(34)17-22)39-13-11-35-12-14-39)38-30(21)40(31(25)41)23-15-20-5-1-4-8-29(20)42-19-23/h3-12,17-19,30,37,41H,13-16H2,1-2H3,(H,38,39,40);3-12,15,17-18,26,31,36H,13-14,16,19-20H2,1-2H3,(H,37,38,39);2-11,14,16-17,25,30,35-36H,12-13,15,18-19H2,1H3,(H,37,38,39);1-10,16-18,23,35H,11-15,19H2,(H,36,37,38).

What are the key properties of 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one?

6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 2395.49 g/mol, XLogP of 24.42, 20 rotatable bonds, 10 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(2-chloro-4-methylphenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylphenyl)-2-(4-morpholin-2-ylanilino)-8-(1,2,3,4-tetrahydroquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(3,4-dihydro-2H-thiochromen-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chlorophenyl)-8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 157405939), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).