N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate

C228H209BrCl2F5N33O15S — CID 157210131

IUPACN-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate
SMILESCC(C)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C(F)(F)F)cc3n2C2CCC2)cc1.CC(C)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4F)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4Br)cc3n2C2CC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4ccc(Cl)cn4)cc3n2C2CCC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4cccc(Cl)n4)cc3n2C2CCC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4F)cc3n2C2CC2)cc1)C1CC1.Cc1ccc(-c2ccc3c(C#N)c(-c4ccc(NC(=O)O[C@H](C)C5CC5)cc4)n(C4CCC4)c3c2)nc1.Cc1ccnc(Oc2ccc3c(C#N)c(-c4ccc(NC(C)C)cc4)n(C4CCC4)c3c2)n1
InChIInChI=1S/C31H30N4O2.2C30H27ClN4O2.C29H25FN4O3.C28H25F3N4O.C27H25FN4O.C27H27N5O.C26H23BrN4O3S/c1-19-6-15-28(33-18-19)23-11-14-26-27(17-32)30(35(29(26)16-23)25-4-3-5-25)22-9-12-24(13-10-22)34-31(36)37-20(2)21-7-8-21;1-18(19-8-9-19)37-30(36)33-22-13-10-20(11-14-22)29-25(17-32)24-15-12-21(26-6-3-7-28(31)34-26)16-27(24)35(29)23-4-2-5-23;1-18(19-5-6-19)37-30(36)34-23-11-7-20(8-12-23)29-26(16-32)25-13-9-21(27-14-10-22(31)17-33-27)15-28(25)35(29)24-3-2-4-24;1-17(18-4-5-18)36-29(35)33-20-8-6-19(7-9-20)27-24(16-31)23-13-12-22(15-26(23)34(27)21-10-11-21)37-28-25(30)3-2-14-32-28;1-17(2)34-19-10-8-18(9-11-19)26-23(16-32)22-13-12-21(15-25(22)35(26)20-5-3-6-20)36-27-24(28(29,30)31)7-4-14-33-27;1-17(2)31-19-10-8-18(9-11-19)26-23(16-29)22-13-12-21(33-27-24(28)7-4-14-30-27)15-25(22)32(26)20-5-3-6-20;1-17(2)30-20-9-7-19(8-10-20)26-24(16-28)23-12-11-22(33-27-29-14-13-18(3)31-27)15-25(23)32(26)21-5-4-6-21;1-2-14-35(32,33)30-18-7-5-17(6-8-18)25-22(16-28)21-12-11-20(15-24(21)31(25)19-9-10-19)34-26-23(27)4-3-13-29-26/h6,9-16,18,20-21,25H,3-5,7-8H2,1-2H3,(H,34,36);3,6-7,10-16,18-19,23H,2,4-5,8-9H2,1H3,(H,33,36);7-15,17-19,24H,2-6H2,1H3,(H,34,36);2-3,6-9,12-15,17-18,21H,4-5,10-11H2,1H3,(H,33,35);4,7-15,17,20,34H,3,5-6H2,1-2H3;4,7-15,17,20,31H,3,5-6H2,1-2H3;7-15,17,21,30H,4-6H2,1-3H3;3-8,11-13,15,19,30H,2,9-10,14H2,1H3/t20-;2*18-;17-;;;;/m1111..../s1
InChIKeyARUJJQOLGFNNRK-QOONUSHSSA-N
MW3929.26 g/mol
LogP58.96
Rot. Bonds51

About N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate

N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate (PubChem CID 157210131) has the molecular formula C228H209BrCl2F5N33O15S and a molecular weight of 3929.26 g/mol. Its IUPAC name is N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate.

Molecular Properties

Compound NameN-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate
PubChem CID157210131
Molecular FormulaC228H209BrCl2F5N33O15S
Molecular Weight3929.26 g/mol
Exact Mass3924.48
IUPAC NameN-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate
SMILESCC(C)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C(F)(F)F)cc3n2C2CCC2)cc1.CC(C)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4F)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4Br)cc3n2C2CC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4ccc(Cl)cn4)cc3n2C2CCC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4cccc(Cl)n4)cc3n2C2CCC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4F)cc3n2C2CC2)cc1)C1CC1.Cc1ccc(-c2ccc3c(C#N)c(-c4ccc(NC(=O)O[C@H](C)C5CC5)cc4)n(C4CCC4)c3c2)nc1.Cc1ccnc(Oc2ccc3c(C#N)c(-c4ccc(NC(C)C)cc4)n(C4CCC4)c3c2)n1
InChIInChI=1S/C31H30N4O2.2C30H27ClN4O2.C29H25FN4O3.C28H25F3N4O.C27H25FN4O.C27H27N5O.C26H23BrN4O3S/c1-19-6-15-28(33-18-19)23-11-14-26-27(17-32)30(35(29(26)16-23)25-4-3-5-25)22-9-12-24(13-10-22)34-31(36)37-20(2)21-7-8-21;1-18(19-8-9-19)37-30(36)33-22-13-10-20(11-14-22)29-25(17-32)24-15-12-21(26-6-3-7-28(31)34-26)16-27(24)35(29)23-4-2-5-23;1-18(19-5-6-19)37-30(36)34-23-11-7-20(8-12-23)29-26(16-32)25-13-9-21(27-14-10-22(31)17-33-27)15-28(25)35(29)24-3-2-4-24;1-17(18-4-5-18)36-29(35)33-20-8-6-19(7-9-20)27-24(16-31)23-13-12-22(15-26(23)34(27)21-10-11-21)37-28-25(30)3-2-14-32-28;1-17(2)34-19-10-8-18(9-11-19)26-23(16-32)22-13-12-21(15-25(22)35(26)20-5-3-6-20)36-27-24(28(29,30)31)7-4-14-33-27;1-17(2)31-19-10-8-18(9-11-19)26-23(16-29)22-13-12-21(33-27-24(28)7-4-14-30-27)15-25(22)32(26)20-5-3-6-20;1-17(2)30-20-9-7-19(8-10-20)26-24(16-28)23-12-11-22(33-27-29-14-13-18(3)31-27)15-25(23)32(26)21-5-4-6-21;1-2-14-35(32,33)30-18-7-5-17(6-8-18)25-22(16-28)21-12-11-20(15-24(21)31(25)19-9-10-19)34-26-23(27)4-3-13-29-26/h6,9-16,18,20-21,25H,3-5,7-8H2,1-2H3,(H,34,36);3,6-7,10-16,18-19,23H,2,4-5,8-9H2,1H3,(H,33,36);7-15,17-19,24H,2-6H2,1H3,(H,34,36);2-3,6-9,12-15,17-18,21H,4-5,10-11H2,1H3,(H,33,35);4,7-15,17,20,34H,3,5-6H2,1-2H3;4,7-15,17,20,31H,3,5-6H2,1-2H3;7-15,17,21,30H,4-6H2,1-3H3;3-8,11-13,15,19,30H,2,9-10,14H2,1H3/t20-;2*18-;17-;;;;/m1111..../s1
InChIKeyARUJJQOLGFNNRK-QOONUSHSSA-N
XLogP58.96
TPSA627.50 Ų
H-Bond Donors8
H-Bond Acceptors43
Rotatable Bonds51
Heavy Atoms285
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003929.26
LogP ≤ 558.96
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1043

Analyze N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate with MolForge

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Related Compounds

CID 157153677
CID 157153677
1-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-3-propan-2-ylurea;1-cyclobutyl-2-[2-(propan-2-ylamino)pyrimidin-5-yl]-6-pyrimidin-2-yloxyindole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate;2-[4-[1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]-1,2-thiazolidine 1,1-dioxide;propan-2-yl N-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[5-[1-(azetidin-1-yl)-3-cyano-6-pyrimidin-2-yloxy-1H-inden-2-yl]-2-pyridinyl]carbamate
CID 157159756
N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]propane-1-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]-3-propan-2-ylurea;1-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]-3-propan-2-ylurea;N-[4-[3-cyano-1-cyclopropyl-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(2,2-difluoroethoxy)indol-2-yl]phenyl]carbamate
CID 157180987
CID 157301426
CID 157301426
N-[4-[3-cyano-1-(cyclopropylmethyl)-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(4-methylpyrimidin-2-yl)oxyindol-2-yl]-3-methylphenyl]carbamate;1-(cyclopropylmethyl)-6-(2-methylsulfonylethoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-(cyclopropylmethyl)-6-(3-methylsulfonylpropoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate
CID 157344993
CID 157438060
CID 157438060
CID 157632056
CID 157632056
CID 157834402
CID 157834402
CID 157936386
CID 157936386
CID 157949272
CID 157949272
CID 158091194
CID 158091194
6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide
CID 158360255

Frequently Asked Questions

What is the IUPAC name of N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate?
The IUPAC name of N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate (CID 157210131) is N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate.
What is the SMILES notation for N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate?
The canonical SMILES for N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate is CC(C)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C(F)(F)F)cc3n2C2CCC2)cc1.CC(C)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4F)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4Br)cc3n2C2CC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4ccc(Cl)cn4)cc3n2C2CCC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4cccc(Cl)n4)cc3n2C2CCC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4F)cc3n2C2CC2)cc1)C1CC1.Cc1ccc(-c2ccc3c(C#N)c(-c4ccc(NC(=O)O[C@H](C)C5CC5)cc4)n(C4CCC4)c3c2)nc1.Cc1ccnc(Oc2ccc3c(C#N)c(-c4ccc(NC(C)C)cc4)n(C4CCC4)c3c2)n1.
What is the InChIKey of N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate?
The InChIKey is ARUJJQOLGFNNRK-QOONUSHSSA-N. The full InChI is InChI=1S/C31H30N4O2.2C30H27ClN4O2.C29H25FN4O3.C28H25F3N4O.C27H25FN4O.C27H27N5O.C26H23BrN4O3S/c1-19-6-15-28(33-18-19)23-11-14-26-27(17-32)30(35(29(26)16-23)25-4-3-5-25)22-9-12-24(13-10-22)34-31(36)37-20(2)21-7-8-21;1-18(19-8-9-19)37-30(36)33-22-13-10-20(11-14-22)29-25(17-32)24-15-12-21(26-6-3-7-28(31)34-26)16-27(24)35(29)23-4-2-5-23;1-18(19-5-6-19)37-30(36)34-23-11-7-20(8-12-23)29-26(16-32)25-13-9-21(27-14-10-22(31)17-33-27)15-28(25)35(29)24-3-2-4-24;1-17(18-4-5-18)36-29(35)33-20-8-6-19(7-9-20)27-24(16-31)23-13-12-22(15-26(23)34(27)21-10-11-21)37-28-25(30)3-2-14-32-28;1-17(2)34-19-10-8-18(9-11-19)26-23(16-32)22-13-12-21(15-25(22)35(26)20-5-3-6-20)36-27-24(28(29,30)31)7-4-14-33-27;1-17(2)31-19-10-8-18(9-11-19)26-23(16-29)22-13-12-21(33-27-24(28)7-4-14-30-27)15-25(22)32(26)20-5-3-6-20;1-17(2)30-20-9-7-19(8-10-20)26-24(16-28)23-12-11-22(33-27-29-14-13-18(3)31-27)15-25(23)32(26)21-5-4-6-21;1-2-14-35(32,33)30-18-7-5-17(6-8-18)25-22(16-28)21-12-11-20(15-24(21)31(25)19-9-10-19)34-26-23(27)4-3-13-29-26/h6,9-16,18,20-21,25H,3-5,7-8H2,1-2H3,(H,34,36);3,6-7,10-16,18-19,23H,2,4-5,8-9H2,1H3,(H,33,36);7-15,17-19,24H,2-6H2,1H3,(H,34,36);2-3,6-9,12-15,17-18,21H,4-5,10-11H2,1H3,(H,33,35);4,7-15,17,20,34H,3,5-6H2,1-2H3;4,7-15,17,20,31H,3,5-6H2,1-2H3;7-15,17,21,30H,4-6H2,1-3H3;3-8,11-13,15,19,30H,2,9-10,14H2,1H3/t20-;2*18-;17-;;;;/m1111..../s1.
What are the key properties of N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate?
N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate has a molecular weight of 3929.26 g/mol, XLogP of 58.96, 51 rotatable bonds, 8 hydrogen bond donors, and 43 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate is sourced from PubChem (CID 157210131), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).