6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide

C135H134ClF12N25O13S6 — CID 158360255

About 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide

6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide (PubChem CID 158360255) has the molecular formula C135H134ClF12N25O13S6 and a molecular weight of 2770.55 g/mol. Its IUPAC name is 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide
• PubChem CID: 158360255
• Molecular Formula: C135H134ClF12N25O13S6
• Molecular Weight: 2770.55 g/mol
• Exact Mass: 2767.84
• IUPAC Name: 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide
• SMILES: CC(C)NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C3CCCC3)c2c1.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1)C1CC1.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(CF)ccc12
• InChI: InChI=1S/C25H28N4O3S.C24H25FN4O2S.C22H20F4N4O2S.C22H21F3N4O2S.C21H18ClF3N4O2S.C21H22FN5O2S/c1-16(17-7-8-17)28-33(30,31)20-10-12-23(27-15-20)25-22(14-26)21-11-9-19(32-2)13-24(21)29(25)18-5-3-4-6-18;1-15(17-6-7-17)28-32(30,31)19-8-10-22(27-14-19)24-21(13-26)20-9-5-16(12-25)11-23(20)29(24)18-3-2-4-18;1-13(22(24,25)26)29-33(31,32)16-6-8-19(28-12-16)21-18(11-27)17-7-5-14(10-23)9-20(17)30(21)15-3-2-4-15;23-9-14-4-6-18-19(12-26)22(29(21(18)8-14)16-2-1-3-16)20-7-5-17(13-27-20)32(30,31)28-15(10-24)11-25;1-12(21(23,24)25)28-32(30,31)15-6-7-18(27-11-15)20-17(10-26)16-9-13(22)5-8-19(16)29(20)14-3-2-4-14;1-13(2)26-30(28,29)16-11-24-21(25-12-16)20-18(10-23)17-7-6-14(9-22)8-19(17)27(20)15-4-3-5-15/h9-13,15-18,28H,3-8H2,1-2H3;5,8-11,14-15,17-18,28H,2-4,6-7,12H2,1H3;5-9,12-13,15,29H,2-4,10H2,1H3;4-8,13,15-16,28H,1-3,9-11H2;5-9,11-12,14,28H,2-4H2,1H3;6-8,11-13,15,26H,3-5,9H2,1-2H3/t16-;15-;13-;;12-;/m001.1./s1
• InChIKey: GTJMEAQVWYAXAH-LNMLNVNISA-N
• XLogP: 28.01
• TPSA: 548.80 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 32
• Rotatable Bonds: 39
• Heavy Atoms: 192
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2770.55
LogP ≤ 5	28.01
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

The IUPAC name of 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide (CID 158360255) is 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide.

What is the SMILES notation for 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

The canonical SMILES for 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide is CC(C)NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C3CCCC3)c2c1.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1)C1CC1.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(CF)ccc12.

What is the InChIKey of 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

The InChIKey is GTJMEAQVWYAXAH-LNMLNVNISA-N. The full InChI is InChI=1S/C25H28N4O3S.C24H25FN4O2S.C22H20F4N4O2S.C22H21F3N4O2S.C21H18ClF3N4O2S.C21H22FN5O2S/c1-16(17-7-8-17)28-33(30,31)20-10-12-23(27-15-20)25-22(14-26)21-11-9-19(32-2)13-24(21)29(25)18-5-3-4-6-18;1-15(17-6-7-17)28-32(30,31)19-8-10-22(27-14-19)24-21(13-26)20-9-5-16(12-25)11-23(20)29(24)18-3-2-4-18;1-13(22(24,25)26)29-33(31,32)16-6-8-19(28-12-16)21-18(11-27)17-7-5-14(10-23)9-20(17)30(21)15-3-2-4-15;23-9-14-4-6-18-19(12-26)22(29(21(18)8-14)16-2-1-3-16)20-7-5-17(13-27-20)32(30,31)28-15(10-24)11-25;1-12(21(23,24)25)28-32(30,31)15-6-7-18(27-11-15)20-17(10-26)16-9-13(22)5-8-19(16)29(20)14-3-2-4-14;1-13(2)26-30(28,29)16-11-24-21(25-12-16)20-18(10-23)17-7-6-14(9-22)8-19(17)27(20)15-4-3-5-15/h9-13,15-18,28H,3-8H2,1-2H3;5,8-11,14-15,17-18,28H,2-4,6-7,12H2,1H3;5-9,12-13,15,29H,2-4,10H2,1H3;4-8,13,15-16,28H,1-3,9-11H2;5-9,11-12,14,28H,2-4H2,1H3;6-8,11-13,15,26H,3-5,9H2,1-2H3/t16-;15-;13-;;12-;/m001.1./s1.

What are the key properties of 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide has a molecular weight of 2770.55 g/mol, XLogP of 28.01, 39 rotatable bonds, 6 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide is sourced from PubChem (CID 158360255), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).