3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide

C120H133ClF6N42O8 — CID 157237985

About 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide

3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide (PubChem CID 157237985) has the molecular formula C120H133ClF6N42O8 and a molecular weight of 2441.11 g/mol. Its IUPAC name is 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide.

Molecular Properties

• Compound Name: 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide
• PubChem CID: 157237985
• Molecular Formula: C120H133ClF6N42O8
• Molecular Weight: 2441.11 g/mol
• Exact Mass: 2439.09
• IUPAC Name: 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide
• SMILES: CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nccc4ccc(Cl)cc34)cnc2N)CC1.C[C@H]1CN(c2cccnc2NC(=O)c2nc(-c3ncccc3OC(F)(F)F)cnc2N)CC[C@H]1N.Nc1ncc(-c2cccc(N3CCOCC3)c2)nc1C(=O)Nc1ncccc1N1CCC(N)CC1.Nc1ncc(-c2cccc(N3CCOCC3)n2)nc1C(=O)Nc1ncccc1N1CCC(N)CC1.Nc1ncc(-c2nc(N3CCC3)ccc2C(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)CC1
• InChI: InChI=1S/C25H25ClN8O.C25H30N8O2.C24H26F3N9O.C24H29N9O2.C22H23F3N8O2/c1-25(28)7-11-34(12-8-25)19-3-2-9-30-23(19)33-24(35)21-22(27)31-14-18(32-21)20-17-13-16(26)5-4-15(17)6-10-29-20;26-18-6-9-33(10-7-18)21-5-2-8-28-24(21)31-25(34)22-23(27)29-16-20(30-22)17-3-1-4-19(15-17)32-11-13-35-14-12-32;25-24(26,27)15-4-5-18(36-9-2-10-36)33-19(15)16-13-31-21(29)20(32-16)23(37)34-22-17(3-1-8-30-22)35-11-6-14(28)7-12-35;25-16-6-9-32(10-7-16)19-4-2-8-27-23(19)31-24(34)21-22(26)28-15-18(30-21)17-3-1-5-20(29-17)33-11-13-35-14-12-33;1-12-11-33(9-6-13(12)26)15-4-2-8-29-20(15)32-21(34)18-19(27)30-10-14(31-18)17-16(5-3-7-28-17)35-22(23,24)25/h2-6,9-10,13-14H,7-8,11-12,28H2,1H3,(H2,27,31)(H,30,33,35);1-5,8,15-16,18H,6-7,9-14,26H2,(H2,27,29)(H,28,31,34);1,3-5,8,13-14H,2,6-7,9-12,28H2,(H2,29,31)(H,30,34,37);1-5,8,15-16H,6-7,9-14,25H2,(H2,26,28)(H,27,31,34);2-5,7-8,10,12-13H,6,9,11,26H2,1H3,(H2,27,30)(H,29,32,34)/t;;;;12-,13+/m....0/s1
• InChIKey: AUWFYFRURRZMOP-CDNBUKKPSA-N
• XLogP: 13.33
• TPSA: 704.22 Ų
• H-Bond Donors: 15
• H-Bond Acceptors: 45
• Rotatable Bonds: 24
• Heavy Atoms: 177
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2441.11
LogP ≤ 5	13.33
H-Bond Donors ≤ 5	15
H-Bond Acceptors ≤ 10	45

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide?

The IUPAC name of 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide (CID 157237985) is 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide.

What is the SMILES notation for 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide?

The canonical SMILES for 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide is CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nccc4ccc(Cl)cc34)cnc2N)CC1.C[C@H]1CN(c2cccnc2NC(=O)c2nc(-c3ncccc3OC(F)(F)F)cnc2N)CC[C@H]1N.Nc1ncc(-c2cccc(N3CCOCC3)c2)nc1C(=O)Nc1ncccc1N1CCC(N)CC1.Nc1ncc(-c2cccc(N3CCOCC3)n2)nc1C(=O)Nc1ncccc1N1CCC(N)CC1.Nc1ncc(-c2nc(N3CCC3)ccc2C(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)CC1.

What is the InChIKey of 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide?

The InChIKey is AUWFYFRURRZMOP-CDNBUKKPSA-N. The full InChI is InChI=1S/C25H25ClN8O.C25H30N8O2.C24H26F3N9O.C24H29N9O2.C22H23F3N8O2/c1-25(28)7-11-34(12-8-25)19-3-2-9-30-23(19)33-24(35)21-22(27)31-14-18(32-21)20-17-13-16(26)5-4-15(17)6-10-29-20;26-18-6-9-33(10-7-18)21-5-2-8-28-24(21)31-25(34)22-23(27)29-16-20(30-22)17-3-1-4-19(15-17)32-11-13-35-14-12-32;25-24(26,27)15-4-5-18(36-9-2-10-36)33-19(15)16-13-31-21(29)20(32-16)23(37)34-22-17(3-1-8-30-22)35-11-6-14(28)7-12-35;25-16-6-9-32(10-7-16)19-4-2-8-27-23(19)31-24(34)21-22(26)28-15-18(30-21)17-3-1-5-20(29-17)33-11-13-35-14-12-33;1-12-11-33(9-6-13(12)26)15-4-2-8-29-20(15)32-21(34)18-19(27)30-10-14(31-18)17-16(5-3-7-28-17)35-22(23,24)25/h2-6,9-10,13-14H,7-8,11-12,28H2,1H3,(H2,27,31)(H,30,33,35);1-5,8,15-16,18H,6-7,9-14,26H2,(H2,27,29)(H,28,31,34);1,3-5,8,13-14H,2,6-7,9-12,28H2,(H2,29,31)(H,30,34,37);1-5,8,15-16H,6-7,9-14,25H2,(H2,26,28)(H,27,31,34);2-5,7-8,10,12-13H,6,9,11,26H2,1H3,(H2,27,30)(H,29,32,34)/t;;;;12-,13+/m....0/s1.

What are the key properties of 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide?

3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide has a molecular weight of 2441.11 g/mol, XLogP of 13.33, 24 rotatable bonds, 15 hydrogen bond donors, and 45 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide is sourced from PubChem (CID 157237985), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).