3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide

C140H155F14N53O8 — CID 158445652

IUPAC3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide
SMILESCC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(N4CCC(F)(F)CC4)ncc3F)cnc2N)CC1.CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(N4CCOCC4)ncc3F)cnc2N)CC1.CCC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3ncccc3F)cnc2N)CC1.CN(C)c1ccc(C(F)(F)F)c(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(N)CC3)n2)n1.C[C@H]1CN(c2cccnc2NC(=O)c2nc(-c3ncccc3OC(F)(F)F)cnc2N)CC[C@H]1N.Nc1ncc(-c2cccc3[nH]c(C(F)(F)F)cc23)nc1C(=O)Nc1ncccc1N1CCC(N)CC1
InChIInChI=1S/C25H29F3N10O.C24H23F3N8O.C24H29FN10O2.C23H26F3N9O.C22H23F3N8O2.C22H25FN8O/c1-24(30)4-9-37(10-5-24)17-3-2-8-31-21(17)36-22(39)19-20(29)32-14-16(34-19)18-15(26)13-33-23(35-18)38-11-6-25(27,28)7-12-38;25-24(26,27)19-11-15-14(3-1-4-16(15)32-19)17-12-31-21(29)20(33-17)23(36)34-22-18(5-2-8-30-22)35-9-6-13(28)7-10-35;1-24(27)4-7-34(8-5-24)17-3-2-6-28-21(17)33-22(36)19-20(26)29-14-16(31-19)18-15(25)13-30-23(32-18)35-9-11-37-12-10-35;1-34(2)17-6-5-14(23(24,25)26)18(32-17)15-12-30-20(28)19(31-15)22(36)33-21-16(4-3-9-29-21)35-10-7-13(27)8-11-35;1-12-11-33(9-6-13(12)26)15-4-2-8-29-20(15)32-21(34)18-19(27)30-10-14(31-18)17-16(5-3-7-28-17)35-22(23,24)25;1-2-22(25)7-11-31(12-8-22)16-6-4-10-27-20(16)30-21(32)18-19(24)28-13-15(29-18)17-14(23)5-3-9-26-17/h2-3,8,13-14H,4-7,9-12,30H2,1H3,(H2,29,32)(H,31,36,39);1-5,8,11-13,32H,6-7,9-10,28H2,(H2,29,31)(H,30,34,36);2-3,6,13-14H,4-5,7-12,27H2,1H3,(H2,26,29)(H,28,33,36);3-6,9,12-13H,7-8,10-11,27H2,1-2H3,(H2,28,30)(H,29,33,36);2-5,7-8,10,12-13H,6,9,11,26H2,1H3,(H2,27,30)(H,29,32,34);3-6,9-10,13H,2,7-8,11-12,25H2,1H3,(H2,24,28)(H,27,30,32)/t;;;;12-,13+;/m....0./s1
InChIKeyHDIZGUFLKRLJOH-RDXYCMCGSA-N
MW2974.11 g/mol
LogP16.35
Rot. Bonds29

About 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide

3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide (PubChem CID 158445652) has the molecular formula C140H155F14N53O8 and a molecular weight of 2974.11 g/mol. Its IUPAC name is 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide.

Molecular Properties

Compound Name3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide
PubChem CID158445652
Molecular FormulaC140H155F14N53O8
Molecular Weight2974.11 g/mol
Exact Mass2972.31
IUPAC Name3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide
SMILESCC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(N4CCC(F)(F)CC4)ncc3F)cnc2N)CC1.CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(N4CCOCC4)ncc3F)cnc2N)CC1.CCC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3ncccc3F)cnc2N)CC1.CN(C)c1ccc(C(F)(F)F)c(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(N)CC3)n2)n1.C[C@H]1CN(c2cccnc2NC(=O)c2nc(-c3ncccc3OC(F)(F)F)cnc2N)CC[C@H]1N.Nc1ncc(-c2cccc3[nH]c(C(F)(F)F)cc23)nc1C(=O)Nc1ncccc1N1CCC(N)CC1
InChIInChI=1S/C25H29F3N10O.C24H23F3N8O.C24H29FN10O2.C23H26F3N9O.C22H23F3N8O2.C22H25FN8O/c1-24(30)4-9-37(10-5-24)17-3-2-8-31-21(17)36-22(39)19-20(29)32-14-16(34-19)18-15(26)13-33-23(35-18)38-11-6-25(27,28)7-12-38;25-24(26,27)19-11-15-14(3-1-4-16(15)32-19)17-12-31-21(29)20(33-17)23(36)34-22-18(5-2-8-30-22)35-9-6-13(28)7-10-35;1-24(27)4-7-34(8-5-24)17-3-2-6-28-21(17)33-22(36)19-20(26)29-14-16(31-19)18-15(25)13-30-23(32-18)35-9-11-37-12-10-35;1-34(2)17-6-5-14(23(24,25)26)18(32-17)15-12-30-20(28)19(31-15)22(36)33-21-16(4-3-9-29-21)35-10-7-13(27)8-11-35;1-12-11-33(9-6-13(12)26)15-4-2-8-29-20(15)32-21(34)18-19(27)30-10-14(31-18)17-16(5-3-7-28-17)35-22(23,24)25;1-2-22(25)7-11-31(12-8-22)16-6-4-10-27-20(16)30-21(32)18-19(24)28-13-15(29-18)17-14(23)5-3-9-26-17/h2-3,8,13-14H,4-7,9-12,30H2,1H3,(H2,29,32)(H,31,36,39);1-5,8,11-13,32H,6-7,9-10,28H2,(H2,29,31)(H,30,34,36);2-3,6,13-14H,4-5,7-12,27H2,1H3,(H2,26,29)(H,28,33,36);3-6,9,12-13H,7-8,10-11,27H2,1-2H3,(H2,28,30)(H,29,33,36);2-5,7-8,10,12-13H,6,9,11,26H2,1H3,(H2,27,30)(H,29,32,34);3-6,9-10,13H,2,7-8,11-12,25H2,1H3,(H2,24,28)(H,27,30,32)/t;;;;12-,13+;/m....0./s1
InChIKeyHDIZGUFLKRLJOH-RDXYCMCGSA-N
XLogP16.35
TPSA872.50 Ų
H-Bond Donors19
H-Bond Acceptors54
Rotatable Bonds29
Heavy Atoms215
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002974.11
LogP ≤ 516.35
H-Bond Donors ≤ 519
H-Bond Acceptors ≤ 1054

Analyze 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

2-(5-fluoro-1H-indol-4-yl)-4-morpholin-4-yl-6-[(4-morpholin-4-ylpiperidin-1-yl)methyl]furo[3,2-d]pyrimidine
CID 25124700
2-[4-[[2-(5-fluoro-1H-indol-4-yl)-4-morpholin-4-ylfuro[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-methylpropanamide
CID 25124702
3-amino-6-[5-[[3-[[3-[4-amino-4-(methoxymethyl)piperidin-1-yl]pyridin-2-yl]carbamoyl]-5-[3-(trifluoromethoxy)pyridin-2-yl]pyrazin-2-yl]amino]-3-cyanopyridin-2-yl]-N-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]pyrazine-2-carboxamide
CID 132234333
3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[5-[[3-[[3-(4-aminopiperidin-1-yl)-2-pyridinyl]carbamoyl]-5-[3-(trifluoromethoxy)-2-pyridinyl]pyrazin-2-yl]amino]-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide
CID 135181604
3-amino-N-[3-[4-amino-4-(hydroxymethyl)piperidin-1-yl]-2-pyridinyl]-6-[5-[[3-[[3-[4-amino-4-(hydroxymethyl)piperidin-1-yl]-2-pyridinyl]carbamoyl]-5-[3-(trifluoromethoxy)-2-pyridinyl]pyrazin-2-yl]amino]-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide
CID 135181605
(2R)-N-[3-[5-fluoro-2-[[5-[2-(methylamino)-2-oxoethoxy]-3-pyridinyl]amino]pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide
CID 155228609
(2R)-N-[3-[5-fluoro-2-[[6-(2-hydroxyethyl)-5-methoxy-3-pyridinyl]amino]pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide
CID 155228615
3-amino-6-(2-amino-5-chloropyrimidin-4-yl)-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(2-carbamoyl-5-fluoropyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-cyano-5-(trifluoromethyl)pyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[4-ethoxy-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(1H-indol-4-yl)pyrazine-2-carboxamide
CID 157121693
3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(7-chloroisoquinolin-1-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(azetidin-1-yl)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(6-morpholin-4-yl-2-pyridinyl)pyrazine-2-carboxamide
CID 157237985
3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(3-methoxy-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(3-methyl-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-morpholin-4-yl-5-(trifluoromethyl)pyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(2-morpholin-4-yl-1,3-thiazol-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-morpholin-4-yl-5-(trifluoromethyl)pyrimidin-4-yl]pyrazine-2-carboxamide
CID 157298887
3-amino-N-[3-(4-amino-3-methylpiperidin-1-yl)-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[3,6-bis(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(3-morpholin-4-ylphenyl)pyrazine-2-carboxamide;3-amino-6-(6-fluoroquinazolin-4-yl)-N-(3-piperidin-1-yl-2-pyridinyl)pyrazine-2-carboxamide;3-amino-6-[6-morpholin-4-yl-3-(trifluoromethyl)-2-pyridinyl]-N-(3-piperidin-1-yl-2-pyridinyl)pyrazine-2-carboxamide;methanamine
CID 157362098
3-amino-N-[3-[(1R,5S)-8-amino-3-azabicyclo[3.2.1]octan-3-yl]-2-pyridinyl]-6-[6-morpholin-4-yl-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(3-cyano-4-methoxy-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-(5,6,7,8-tetrahydroquinazolin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-propylpiperidin-1-yl)-2-pyridinyl]-6-[3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide
CID 157416224

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide?
The IUPAC name of 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide (CID 158445652) is 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide.
What is the SMILES notation for 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide?
The canonical SMILES for 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide is CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(N4CCC(F)(F)CC4)ncc3F)cnc2N)CC1.CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(N4CCOCC4)ncc3F)cnc2N)CC1.CCC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3ncccc3F)cnc2N)CC1.CN(C)c1ccc(C(F)(F)F)c(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(N)CC3)n2)n1.C[C@H]1CN(c2cccnc2NC(=O)c2nc(-c3ncccc3OC(F)(F)F)cnc2N)CC[C@H]1N.Nc1ncc(-c2cccc3[nH]c(C(F)(F)F)cc23)nc1C(=O)Nc1ncccc1N1CCC(N)CC1.
What is the InChIKey of 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide?
The InChIKey is HDIZGUFLKRLJOH-RDXYCMCGSA-N. The full InChI is InChI=1S/C25H29F3N10O.C24H23F3N8O.C24H29FN10O2.C23H26F3N9O.C22H23F3N8O2.C22H25FN8O/c1-24(30)4-9-37(10-5-24)17-3-2-8-31-21(17)36-22(39)19-20(29)32-14-16(34-19)18-15(26)13-33-23(35-18)38-11-6-25(27,28)7-12-38;25-24(26,27)19-11-15-14(3-1-4-16(15)32-19)17-12-31-21(29)20(33-17)23(36)34-22-18(5-2-8-30-22)35-9-6-13(28)7-10-35;1-24(27)4-7-34(8-5-24)17-3-2-6-28-21(17)33-22(36)19-20(26)29-14-16(31-19)18-15(25)13-30-23(32-18)35-9-11-37-12-10-35;1-34(2)17-6-5-14(23(24,25)26)18(32-17)15-12-30-20(28)19(31-15)22(36)33-21-16(4-3-9-29-21)35-10-7-13(27)8-11-35;1-12-11-33(9-6-13(12)26)15-4-2-8-29-20(15)32-21(34)18-19(27)30-10-14(31-18)17-16(5-3-7-28-17)35-22(23,24)25;1-2-22(25)7-11-31(12-8-22)16-6-4-10-27-20(16)30-21(32)18-19(24)28-13-15(29-18)17-14(23)5-3-9-26-17/h2-3,8,13-14H,4-7,9-12,30H2,1H3,(H2,29,32)(H,31,36,39);1-5,8,11-13,32H,6-7,9-10,28H2,(H2,29,31)(H,30,34,36);2-3,6,13-14H,4-5,7-12,27H2,1H3,(H2,26,29)(H,28,33,36);3-6,9,12-13H,7-8,10-11,27H2,1-2H3,(H2,28,30)(H,29,33,36);2-5,7-8,10,12-13H,6,9,11,26H2,1H3,(H2,27,30)(H,29,32,34);3-6,9-10,13H,2,7-8,11-12,25H2,1H3,(H2,24,28)(H,27,30,32)/t;;;;12-,13+;/m....0./s1.
What are the key properties of 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide?
3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide has a molecular weight of 2974.11 g/mol, XLogP of 16.35, 29 rotatable bonds, 19 hydrogen bond donors, and 54 hydrogen bond acceptors.
Where does this data come from?
All data for 3-amino-N-[3-(4-amino-4-ethylpiperidin-1-yl)-2-pyridinyl]-6-(3-fluoro-2-pyridinyl)pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-[2-(4,4-difluoropiperidin-1-yl)-5-fluoropyrimidin-4-yl]pyrazine-2-carboxamide;3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)-2-pyridinyl]-6-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)pyrazine-2-carboxamide;3-amino-N-[3-[(3S,4R)-4-amino-3-methylpiperidin-1-yl]-2-pyridinyl]-6-[3-(trifluoromethoxy)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[6-(dimethylamino)-3-(trifluoromethyl)-2-pyridinyl]pyrazine-2-carboxamide;3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-[2-(trifluoromethyl)-1H-indol-4-yl]pyrazine-2-carboxamide is sourced from PubChem (CID 158445652), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).