2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine

C76H86N36 — CID 157259784

IUPAC2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine
SMILESCN1CCN(c2ccc(Nc3nccn4c(-c5cnn(C)c5)cnc34)cn2)CC1.Cn1cc(-c2cnc3c(Nc4ccc(NCCN)nc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnc(N5CCC(N)CC5)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnc(N5CC[C@@H](N)C5)c4)nccn23)cn1
InChIInChI=1S/2C20H23N9.C19H21N9.C17H19N9/c1-27-13-14(11-25-27)17-12-24-20-19(23-6-9-29(17)20)26-16-2-5-22-18(10-16)28-7-3-15(21)4-8-28;1-26-7-9-28(10-8-26)18-4-3-16(12-22-18)25-19-20-23-13-17(29(20)6-5-21-19)15-11-24-27(2)14-15;1-26-11-13(9-24-26)16-10-23-19-18(22-5-7-28(16)19)25-15-2-4-21-17(8-15)27-6-3-14(20)12-27;1-25-11-12(8-23-25)14-10-22-17-16(20-6-7-26(14)17)24-13-2-3-15(21-9-13)19-5-4-18/h2,5-6,9-13,15H,3-4,7-8,21H2,1H3,(H,22,23,26);3-6,11-14H,7-10H2,1-2H3,(H,21,25);2,4-5,7-11,14H,3,6,12,20H2,1H3,(H,21,22,25);2-3,6-11H,4-5,18H2,1H3,(H,19,21)(H,20,24)/t;;14-;/m..1./s1
InChIKeyAXHZIKSYZFDTHZ-PIXPJRFFSA-N
MW1503.78 g/mol
LogP7.66
Rot. Bonds18

About 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine

2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine (PubChem CID 157259784) has the molecular formula C76H86N36 and a molecular weight of 1503.78 g/mol. Its IUPAC name is 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

Compound Name2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine
PubChem CID157259784
Molecular FormulaC76H86N36
Molecular Weight1503.78 g/mol
Exact Mass1502.78
IUPAC Name2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine
SMILESCN1CCN(c2ccc(Nc3nccn4c(-c5cnn(C)c5)cnc34)cn2)CC1.Cn1cc(-c2cnc3c(Nc4ccc(NCCN)nc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnc(N5CCC(N)CC5)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnc(N5CC[C@@H](N)C5)c4)nccn23)cn1
InChIInChI=1S/2C20H23N9.C19H21N9.C17H19N9/c1-27-13-14(11-25-27)17-12-24-20-19(23-6-9-29(17)20)26-16-2-5-22-18(10-16)28-7-3-15(21)4-8-28;1-26-7-9-28(10-8-26)18-4-3-16(12-22-18)25-19-20-23-13-17(29(20)6-5-21-19)15-11-24-27(2)14-15;1-26-11-13(9-24-26)16-10-23-19-18(22-5-7-28(16)19)25-15-2-4-21-17(8-15)27-6-3-14(20)12-27;1-25-11-12(8-23-25)14-10-22-17-16(20-6-7-26(14)17)24-13-2-3-15(21-9-13)19-5-4-18/h2,5-6,9-13,15H,3-4,7-8,21H2,1H3,(H,22,23,26);3-6,11-14H,7-10H2,1-2H3,(H,21,25);2,4-5,7-11,14H,3,6,12,20H2,1H3,(H,21,22,25);2-3,6-11H,4-5,18H2,1H3,(H,19,21)(H,20,24)/t;;14-;/m..1./s1
InChIKeyAXHZIKSYZFDTHZ-PIXPJRFFSA-N
XLogP7.66
TPSA394.77 Ų
H-Bond Donors8
H-Bond Acceptors36
Rotatable Bonds18
Heavy Atoms112
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001503.78
LogP ≤ 57.66
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1036

Analyze 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

Savolitinib
CID 68289010
1-{1-[8-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]piperidin-4-yl}-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one
CID 66802145
5-Chloranyl-4-Imidazo[1,2-A]pyridin-3-Yl-N-(3-Methyl-1-Piperidin-4-Yl-Pyrazol-4-Yl)pyrimidin-2-Amine
CID 122177112
5-Chloranyl-4-Imidazo[1,2-A]pyridin-3-Yl-N-(5-Methyl-1-Piperidin-4-Yl-Pyrazol-4-Yl)pyrimidin-2-Amine
CID 122177111
3-(1-Ethylbenzimidazol-2-yl)-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyrazin-2-amine
CID 25192363
N-piperidin-4-yl-6-[6-(1H-pyrazol-5-yl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine
CID 44448970
6-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-N-piperidin-4-ylpyridin-2-amine
CID 44448973
3-(Imidazo[1,2-a]pyridin-6-ylmethyl)-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine
CID 53261691
8-cyclopentyl-N-(5-piperazin-1-yl-2-pyridinyl)-4,6,8,10,11-pentazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-5-amine
CID 58300060
3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1-methylpyrazol-3-yl)-6-pyrimidin-5-ylimidazo[1,2-a]pyridin-2-amine
CID 62706471
3-[2-[(3-fluoro-2-pyridyl)amino]pyrimidin-5-yl]-N-(1-methyl-4-piperidyl)imidazo[1,2-b]pyridazin-6-amine
CID 66550907
N-(3-fluoro-2-pyridyl)-5-(6-piperazin-1-ylimidazo[1,2-b]pyridazin-3-yl)pyrimidin-2-amine
CID 66551112

Frequently Asked Questions

What is the IUPAC name of 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine?
The IUPAC name of 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine (CID 157259784) is 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine.
What is the SMILES notation for 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine?
The canonical SMILES for 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine is CN1CCN(c2ccc(Nc3nccn4c(-c5cnn(C)c5)cnc34)cn2)CC1.Cn1cc(-c2cnc3c(Nc4ccc(NCCN)nc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnc(N5CCC(N)CC5)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnc(N5CC[C@@H](N)C5)c4)nccn23)cn1.
What is the InChIKey of 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine?
The InChIKey is AXHZIKSYZFDTHZ-PIXPJRFFSA-N. The full InChI is InChI=1S/2C20H23N9.C19H21N9.C17H19N9/c1-27-13-14(11-25-27)17-12-24-20-19(23-6-9-29(17)20)26-16-2-5-22-18(10-16)28-7-3-15(21)4-8-28;1-26-7-9-28(10-8-26)18-4-3-16(12-22-18)25-19-20-23-13-17(29(20)6-5-21-19)15-11-24-27(2)14-15;1-26-11-13(9-24-26)16-10-23-19-18(22-5-7-28(16)19)25-15-2-4-21-17(8-15)27-6-3-14(20)12-27;1-25-11-12(8-23-25)14-10-22-17-16(20-6-7-26(14)17)24-13-2-3-15(21-9-13)19-5-4-18/h2,5-6,9-13,15H,3-4,7-8,21H2,1H3,(H,22,23,26);3-6,11-14H,7-10H2,1-2H3,(H,21,25);2,4-5,7-11,14H,3,6,12,20H2,1H3,(H,21,22,25);2-3,6-11H,4-5,18H2,1H3,(H,19,21)(H,20,24)/t;;14-;/m..1./s1.
What are the key properties of 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine?
2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 1503.78 g/mol, XLogP of 7.66, 18 rotatable bonds, 8 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for 2-N-(2-aminoethyl)-5-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-2,5-diamine;N-[2-(4-aminopiperidin-1-yl)-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[2-[(3R)-3-aminopyrrolidin-1-yl]-4-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 157259784), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).