N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide

C80H96N24O12S4 — CID 157261401

About N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide

N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide (PubChem CID 157261401) has the molecular formula C80H96N24O12S4 and a molecular weight of 1714.07 g/mol. Its IUPAC name is N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide.

Molecular Properties

• Compound Name: N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide
• PubChem CID: 157261401
• Molecular Formula: C80H96N24O12S4
• Molecular Weight: 1714.07 g/mol
• Exact Mass: 1712.65
• IUPAC Name: N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide
• SMILES: CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2ccc(C)nc2)C3=O)s1.CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2ccnc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2ccc(C)nc2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2ccnc(C)c2)C3=O)s1
• InChI: InChI=1S/4C20H24N6O3S/c2*1-12-10-15(4-7-21-12)26-17(28)20(24-19(26)29)5-8-25(9-6-20)13(2)16-11-22-18(30-16)23-14(3)27;2*1-12-4-5-15(10-21-12)26-17(28)20(24-19(26)29)6-8-25(9-7-20)13(2)16-11-22-18(30-16)23-14(3)27/h2*4,7,10-11,13H,5-6,8-9H2,1-3H3,(H,24,29)(H,22,23,27);2*4-5,10-11,13H,6-9H2,1-3H3,(H,24,29)(H,22,23,27)/t4*13-/m1010/s1
• InChIKey: AXMSQAMQUINWGE-QGLFRBIFSA-N
• XLogP: 9.83
• TPSA: 430.12 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 28
• Rotatable Bonds: 16
• Heavy Atoms: 120
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1714.07
LogP ≤ 5	9.83
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	28

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The IUPAC name of N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide (CID 157261401) is N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide.

What is the SMILES notation for N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The canonical SMILES for N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide is CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2ccc(C)nc2)C3=O)s1.CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2ccnc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2ccc(C)nc2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2ccnc(C)c2)C3=O)s1.

What is the InChIKey of N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The InChIKey is AXMSQAMQUINWGE-QGLFRBIFSA-N. The full InChI is InChI=1S/4C20H24N6O3S/c2*1-12-10-15(4-7-21-12)26-17(28)20(24-19(26)29)5-8-25(9-6-20)13(2)16-11-22-18(30-16)23-14(3)27;2*1-12-4-5-15(10-21-12)26-17(28)20(24-19(26)29)6-8-25(9-7-20)13(2)16-11-22-18(30-16)23-14(3)27/h2*4,7,10-11,13H,5-6,8-9H2,1-3H3,(H,24,29)(H,22,23,27);2*4-5,10-11,13H,6-9H2,1-3H3,(H,24,29)(H,22,23,27)/t4*13-/m1010/s1.

What are the key properties of N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide has a molecular weight of 1714.07 g/mol, XLogP of 9.83, 16 rotatable bonds, 8 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-[(1R)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2-methyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(6-methyl-3-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide is sourced from PubChem (CID 157261401), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).