2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine

C134H221N37S2 — CID 157267303

About 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine

2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine (PubChem CID 157267303) has the molecular formula C134H221N37S2 and a molecular weight of 2414.63 g/mol. Its IUPAC name is 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine.

Molecular Properties

• Compound Name: 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine
• PubChem CID: 157267303
• Molecular Formula: C134H221N37S2
• Molecular Weight: 2414.63 g/mol
• Exact Mass: 2412.79
• IUPAC Name: 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine
• SMILES: C.C.C.C.Cc1ccc(C2CCNC(C)(C)C2)cc1.Cc1ccc(N2CCN(C)C(C)C2)s1.Cc1ccc(N2CCN(C)CC2)s1.Cc1cnc(N2CCN(C)C(C)C2)cn1.Cc1cnc(N2CCN(C3CC3)CC2)cn1.Cc1cnc(N2CCN3CCCC3C2)cn1.Cc1cnc(N2CCN3CCCCC3C2)cn1.Cc1cnc(N2CCN3CCCCC3C2)nc1.Cc1cnc(N2CCNC(C)(C)C2)cn1.Cc1cnc(N2C[C@@H](C)N(C)[C@@H](C)C2)cn1.Cc1cnc(N2C[C@@H](C)N[C@@H](C)C2)cn1
• InChI: InChI=1S/C14H21N.2C13H20N4.2C12H18N4.C12H20N4.3C11H18N4.C11H18N2S.C10H16N2S.4CH4/c1-11-4-6-12(7-5-11)13-8-9-15-14(2,3)10-13;1-11-8-15-13(9-14-11)17-7-6-16-5-3-2-4-12(16)10-17;1-11-8-14-13(15-9-11)17-7-6-16-5-3-2-4-12(16)10-17;1-10-8-14-12(9-13-10)16-6-4-15(5-7-16)11-2-3-11;1-10-7-14-12(8-13-10)16-6-5-15-4-2-3-11(15)9-16;1-9-5-14-12(6-13-9)16-7-10(2)15(4)11(3)8-16;1-8-4-13-11(5-12-8)15-6-9(2)14-10(3)7-15;1-9-6-13-10(7-12-9)15-5-4-14-11(2,3)8-15;1-9-6-13-11(7-12-9)15-5-4-14(3)10(2)8-15;1-9-8-13(7-6-12(9)3)11-5-4-10(2)14-11;1-9-3-4-10(13-9)12-7-5-11(2)6-8-12;;;;/h4-7,13,15H,8-10H2,1-3H3;2*8-9,12H,2-7,10H2,1H3;8-9,11H,2-7H2,1H3;7-8,11H,2-6,9H2,1H3;5-6,10-11H,7-8H2,1-4H3;4-5,9-10,14H,6-7H2,1-3H3;6-7,14H,4-5,8H2,1-3H3;6-7,10H,4-5,8H2,1-3H3;4-5,9H,6-8H2,1-3H3;3-4H,5-8H2,1-2H3;4*1H4/t;;;;;10-,11+;9-,10+
• InChIKey: AYDKBSBEIMZIOJ-YMUSUPMUSA-N
• XLogP: 19.03
• TPSA: 300.65 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 39
• Rotatable Bonds: 12
• Heavy Atoms: 173
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2414.63
LogP ≤ 5	19.03
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	39

Frequently Asked Questions

What is the IUPAC name of 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine?

The IUPAC name of 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine (CID 157267303) is 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine.

What is the SMILES notation for 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine?

The canonical SMILES for 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine is C.C.C.C.Cc1ccc(C2CCNC(C)(C)C2)cc1.Cc1ccc(N2CCN(C)C(C)C2)s1.Cc1ccc(N2CCN(C)CC2)s1.Cc1cnc(N2CCN(C)C(C)C2)cn1.Cc1cnc(N2CCN(C3CC3)CC2)cn1.Cc1cnc(N2CCN3CCCC3C2)cn1.Cc1cnc(N2CCN3CCCCC3C2)cn1.Cc1cnc(N2CCN3CCCCC3C2)nc1.Cc1cnc(N2CCNC(C)(C)C2)cn1.Cc1cnc(N2C[C@@H](C)N(C)[C@@H](C)C2)cn1.Cc1cnc(N2C[C@@H](C)N[C@@H](C)C2)cn1.

What is the InChIKey of 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine?

The InChIKey is AYDKBSBEIMZIOJ-YMUSUPMUSA-N. The full InChI is InChI=1S/C14H21N.2C13H20N4.2C12H18N4.C12H20N4.3C11H18N4.C11H18N2S.C10H16N2S.4CH4/c1-11-4-6-12(7-5-11)13-8-9-15-14(2,3)10-13;1-11-8-15-13(9-14-11)17-7-6-16-5-3-2-4-12(16)10-17;1-11-8-14-13(15-9-11)17-7-6-16-5-3-2-4-12(16)10-17;1-10-8-14-12(9-13-10)16-6-4-15(5-7-16)11-2-3-11;1-10-7-14-12(8-13-10)16-6-5-15-4-2-3-11(15)9-16;1-9-5-14-12(6-13-9)16-7-10(2)15(4)11(3)8-16;1-8-4-13-11(5-12-8)15-6-9(2)14-10(3)7-15;1-9-6-13-10(7-12-9)15-5-4-14-11(2,3)8-15;1-9-6-13-11(7-12-9)15-5-4-14(3)10(2)8-15;1-9-8-13(7-6-12(9)3)11-5-4-10(2)14-11;1-9-3-4-10(13-9)12-7-5-11(2)6-8-12;;;;/h4-7,13,15H,8-10H2,1-3H3;2*8-9,12H,2-7,10H2,1H3;8-9,11H,2-7H2,1H3;7-8,11H,2-6,9H2,1H3;5-6,10-11H,7-8H2,1-4H3;4-5,9-10,14H,6-7H2,1-3H3;6-7,14H,4-5,8H2,1-3H3;6-7,10H,4-5,8H2,1-3H3;4-5,9H,6-8H2,1-3H3;3-4H,5-8H2,1-2H3;4*1H4/t;;;;;10-,11+;9-,10+;;;;;;;;.

What are the key properties of 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine?

2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine has a molecular weight of 2414.63 g/mol, XLogP of 19.03, 12 rotatable bonds, 3 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(4-cyclopropylpiperazin-1-yl)-5-methylpyrazine;2,2-dimethyl-4-(4-methylphenyl)piperidine;1,2-dimethyl-4-(5-methylthiophen-2-yl)piperazine;2-(3,3-dimethylpiperazin-1-yl)-5-methylpyrazine;2-(3,4-dimethylpiperazin-1-yl)-5-methylpyrazine;2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5-methylpyrazine;methane;1-methyl-4-(5-methylthiophen-2-yl)piperazine;2-(5-methylpyrazin-2-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;2-(5-methylpyrazin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-(5-methylpyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine;2-methyl-5-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]pyrazine is sourced from PubChem (CID 157267303), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).