5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one

C146H150F5N29O17 — CID 157274061

IUPAC5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
SMILESCC(F)(F)CN1CCn2nc(OCc3ccccc3)cc2C1=O.CC1(F)CC1CN1CCCn2nc(OCc3ccccc3)cc2C1=O.COc1cccnc1N1CCn2nc(OCc3ccccc3)cc2C1=O.Cc1ccc(N2CCn3nc(OCc4cccc(F)c4)cc3C2=O)cc1.Cc1cncc(N2CCn3nc(OCc4ccccc4)cc3C2=O)n1.Cc1nc(N2CCn3nc(OCc4ccccc4)cc3C2=O)ncc1F.O=C1c2cc(OCc3ccccc3)nn2CCCN1CC1CC1.O=C1c2cc(OCc3ccccc3)nn2CCN1CC1CCC1
InChIInChI=1S/C20H18FN3O2.C19H22FN3O2.C19H18N4O3.C18H16FN5O2.C18H17N5O2.2C18H21N3O2.C16H17F2N3O2/c1-14-5-7-17(8-6-14)23-9-10-24-18(20(23)25)12-19(22-24)26-13-15-3-2-4-16(21)11-15;1-19(20)11-15(19)12-22-8-5-9-23-16(18(22)24)10-17(21-23)25-13-14-6-3-2-4-7-14;1-25-16-8-5-9-20-18(16)22-10-11-23-15(19(22)24)12-17(21-23)26-13-14-6-3-2-4-7-14;1-12-14(19)10-20-18(21-12)23-7-8-24-15(17(23)25)9-16(22-24)26-11-13-5-3-2-4-6-13;1-13-10-19-11-16(20-13)22-7-8-23-15(18(22)24)9-17(21-23)25-12-14-5-3-2-4-6-14;22-18-16-11-17(23-13-15-5-2-1-3-6-15)19-21(16)10-4-9-20(18)12-14-7-8-14;22-18-16-11-17(23-13-15-5-2-1-3-6-15)19-21(16)10-9-20(18)12-14-7-4-8-14;1-16(17,18)11-20-7-8-21-13(15(20)22)9-14(19-21)23-10-12-5-3-2-4-6-12/h2-8,11-12H,9-10,13H2,1H3;2-4,6-7,10,15H,5,8-9,11-13H2,1H3;2-9,12H,10-11,13H2,1H3;2-6,9-10H,7-8,11H2,1H3;2-6,9-11H,7-8,12H2,1H3;2*1-3,5-6,11,14H,4,7-10,12-13H2;2-6,9H,7-8,10-11H2,1H3
InChIKeyAYWMJDIKKWKGEM-UHFFFAOYSA-N
MW2677.98 g/mol
LogP21.74
Rot. Bonds37

About 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one

5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one (PubChem CID 157274061) has the molecular formula C146H150F5N29O17 and a molecular weight of 2677.98 g/mol. Its IUPAC name is 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one.

Molecular Properties

Compound Name5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
PubChem CID157274061
Molecular FormulaC146H150F5N29O17
Molecular Weight2677.98 g/mol
Exact Mass2676.17
IUPAC Name5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
SMILESCC(F)(F)CN1CCn2nc(OCc3ccccc3)cc2C1=O.CC1(F)CC1CN1CCCn2nc(OCc3ccccc3)cc2C1=O.COc1cccnc1N1CCn2nc(OCc3ccccc3)cc2C1=O.Cc1ccc(N2CCn3nc(OCc4cccc(F)c4)cc3C2=O)cc1.Cc1cncc(N2CCn3nc(OCc4ccccc4)cc3C2=O)n1.Cc1nc(N2CCn3nc(OCc4ccccc4)cc3C2=O)ncc1F.O=C1c2cc(OCc3ccccc3)nn2CCCN1CC1CC1.O=C1c2cc(OCc3ccccc3)nn2CCN1CC1CCC1
InChIInChI=1S/C20H18FN3O2.C19H22FN3O2.C19H18N4O3.C18H16FN5O2.C18H17N5O2.2C18H21N3O2.C16H17F2N3O2/c1-14-5-7-17(8-6-14)23-9-10-24-18(20(23)25)12-19(22-24)26-13-15-3-2-4-16(21)11-15;1-19(20)11-15(19)12-22-8-5-9-23-16(18(22)24)10-17(21-23)25-13-14-6-3-2-4-7-14;1-25-16-8-5-9-20-18(16)22-10-11-23-15(19(22)24)12-17(21-23)26-13-14-6-3-2-4-7-14;1-12-14(19)10-20-18(21-12)23-7-8-24-15(17(23)25)9-16(22-24)26-11-13-5-3-2-4-6-13;1-13-10-19-11-16(20-13)22-7-8-23-15(18(22)24)9-17(21-23)25-12-14-5-3-2-4-6-14;22-18-16-11-17(23-13-15-5-2-1-3-6-15)19-21(16)10-4-9-20(18)12-14-7-8-14;22-18-16-11-17(23-13-15-5-2-1-3-6-15)19-21(16)10-9-20(18)12-14-7-4-8-14;1-16(17,18)11-20-7-8-21-13(15(20)22)9-14(19-21)23-10-12-5-3-2-4-6-12/h2-8,11-12H,9-10,13H2,1H3;2-4,6-7,10,15H,5,8-9,11-13H2,1H3;2-9,12H,10-11,13H2,1H3;2-6,9-10H,7-8,11H2,1H3;2-6,9-11H,7-8,12H2,1H3;2*1-3,5-6,11,14H,4,7-10,12-13H2;2-6,9H,7-8,10-11H2,1H3
InChIKeyAYWMJDIKKWKGEM-UHFFFAOYSA-N
XLogP21.74
TPSA452.56 Ų
H-Bond Donors
H-Bond Acceptors38
Rotatable Bonds37
Heavy Atoms197
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002677.98
LogP ≤ 521.74
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1038

Analyze 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one with MolForge

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Related Compounds

[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(1,1-difluoroethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-[(3-fluorophenyl)methoxy]-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl]-(4-methylphenyl)methanone;(3-methoxypyrazin-2-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl)methanone;(2-methylpyrimidin-5-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
CID 157614925
[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(1,5-dimethylpyrrol-2-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-methoxypyrazin-2-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(6-methoxy-2-pyridinyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl)methanone;(2-methylpyrimidin-5-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-pyridin-2-ylmethanone
CID 157752910
[2-(1,1-difluoroethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[4-fluoro-3-(2-fluoropropan-2-yl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-methoxypyrazin-2-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl)methanone;(2-methylpyrimidin-5-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
CID 157999380
5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[6-(dimethylamino)-2-pyridinyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(4,5-dimethyl-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(5,6-dimethyl-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(1-methylcyclobutyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methyl-2-pyridinyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-methyl-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
CID 158149835
[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(1,5-dimethylpyrrol-2-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-2-pyridinyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-methoxypyrazin-2-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(6-methoxy-2-pyridinyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2-methylpyrimidin-5-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-pyridin-2-ylmethanone
CID 158342124
[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-methoxypyrazin-2-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(6-methoxy-2-pyridinyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2-methylpyrimidin-5-yl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-pyridin-2-ylmethanone
CID 158487104
cyclopropyl-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;(2,2-difluorocyclopropyl)-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;[(2R,6S)-2,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]-(1-propan-2-ylpyrazol-3-yl)methanone;6-phenoxy-3-[4-[(3S)-3-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyridine;6-phenoxy-3-[4-[(3R)-3-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyridine
CID 158554525
CID 158938763
CID 158938763
5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(3-fluoro-3-methylcyclobutyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(3-fluoro-5-methylphenyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(4-fluoro-3-methylphenyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(4-methylphenyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(2-methylpyrimidin-4-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
CID 159809410
N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-5-methoxy-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-(triazol-2-yl)pyridine-2-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-6-methyl-3-pyrimidin-2-ylpyridine-2-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-5-methoxy-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)pyridine-2-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide
CID 160114796
2-(2-ethoxy-3-pyridinyl)-7-[(4-pyrazol-1-ylphenyl)methyl]-5H-pyrrolo[2,3-d]pyrimidin-6-one;2-(3-fluoro-2-methoxyphenyl)-7-[[4-(triazol-2-yl)phenyl]methyl]-5H-pyrrolo[2,3-d]pyrimidin-6-one;2-[2-(2-methoxyethoxy)-3-pyridinyl]-7-[(4-pyrazol-1-ylphenyl)methyl]-5H-pyrrolo[2,3-d]pyrimidin-6-one;7-methyl-2-(4-propan-2-yl-3-pyridinyl)-9-[(4-pyrazol-1-ylphenyl)methyl]purin-8-one;7-[(4-pyrazol-1-ylphenyl)methyl]-2-[2-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5H-pyrrolo[2,3-d]pyrimidin-6-one
CID 160631625
5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxypyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methyl-2-pyridinyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;2-phenylmethoxy-5-(2,2,2-trifluoroethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
CID 160754531

Frequently Asked Questions

What is the IUPAC name of 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one?
The IUPAC name of 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one (CID 157274061) is 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one.
What is the SMILES notation for 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one?
The canonical SMILES for 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one is CC(F)(F)CN1CCn2nc(OCc3ccccc3)cc2C1=O.CC1(F)CC1CN1CCCn2nc(OCc3ccccc3)cc2C1=O.COc1cccnc1N1CCn2nc(OCc3ccccc3)cc2C1=O.Cc1ccc(N2CCn3nc(OCc4cccc(F)c4)cc3C2=O)cc1.Cc1cncc(N2CCn3nc(OCc4ccccc4)cc3C2=O)n1.Cc1nc(N2CCn3nc(OCc4ccccc4)cc3C2=O)ncc1F.O=C1c2cc(OCc3ccccc3)nn2CCCN1CC1CC1.O=C1c2cc(OCc3ccccc3)nn2CCN1CC1CCC1.
What is the InChIKey of 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one?
The InChIKey is AYWMJDIKKWKGEM-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H18FN3O2.C19H22FN3O2.C19H18N4O3.C18H16FN5O2.C18H17N5O2.2C18H21N3O2.C16H17F2N3O2/c1-14-5-7-17(8-6-14)23-9-10-24-18(20(23)25)12-19(22-24)26-13-15-3-2-4-16(21)11-15;1-19(20)11-15(19)12-22-8-5-9-23-16(18(22)24)10-17(21-23)25-13-14-6-3-2-4-7-14;1-25-16-8-5-9-20-18(16)22-10-11-23-15(19(22)24)12-17(21-23)26-13-14-6-3-2-4-7-14;1-12-14(19)10-20-18(21-12)23-7-8-24-15(17(23)25)9-16(22-24)26-11-13-5-3-2-4-6-13;1-13-10-19-11-16(20-13)22-7-8-23-15(18(22)24)9-17(21-23)25-12-14-5-3-2-4-6-14;22-18-16-11-17(23-13-15-5-2-1-3-6-15)19-21(16)10-4-9-20(18)12-14-7-8-14;22-18-16-11-17(23-13-15-5-2-1-3-6-15)19-21(16)10-9-20(18)12-14-7-4-8-14;1-16(17,18)11-20-7-8-21-13(15(20)22)9-14(19-21)23-10-12-5-3-2-4-6-12/h2-8,11-12H,9-10,13H2,1H3;2-4,6-7,10,15H,5,8-9,11-13H2,1H3;2-9,12H,10-11,13H2,1H3;2-6,9-10H,7-8,11H2,1H3;2-6,9-11H,7-8,12H2,1H3;2*1-3,5-6,11,14H,4,7-10,12-13H2;2-6,9H,7-8,10-11H2,1H3.
What are the key properties of 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one?
5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one has a molecular weight of 2677.98 g/mol, XLogP of 21.74, 37 rotatable bonds, 0 hydrogen bond donors, and 38 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(2-fluoro-2-methylcyclopropyl)methyl]-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(5-fluoro-4-methylpyrimidin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-5-(4-methylphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(3-methoxy-2-pyridinyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(6-methylpyrazin-2-yl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one is sourced from PubChem (CID 157274061), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).