N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide

C89H106ClF2N21O8S — CID 157275152

About N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide

N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide (PubChem CID 157275152) has the molecular formula C89H106ClF2N21O8S and a molecular weight of 1703.48 g/mol. Its IUPAC name is N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide.

Molecular Properties

• Compound Name: N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide
• PubChem CID: 157275152
• Molecular Formula: C89H106ClF2N21O8S
• Molecular Weight: 1703.48 g/mol
• Exact Mass: 1701.79
• IUPAC Name: N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide
• SMILES: CC(C)(C)OCCC(=O)Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cn1.COC(C)CCC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.Cc1ccc2nc(NC(=O)CC3CC(C)(F)C3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCc3ccco3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCc3cccs3)n(C3CCC3)c2n1
• InChI: InChI=1S/C18H19ClFN5O2.C18H23FN4O.C18H20N4O2.C18H20N4OS.C17H24N4O2/c1-18(2,3)27-9-8-15(26)24-17-22-12-5-6-13(19)23-16(12)25(17)14-7-4-11(20)10-21-14;1-11-6-7-14-16(20-11)23(13-4-3-5-13)17(21-14)22-15(24)8-12-9-18(2,19)10-12;2*1-12-7-9-15-17(19-12)22(13-4-2-5-13)18(20-15)21-16(23)10-8-14-6-3-11-24-14;1-11-7-9-14-16(18-11)21(13-5-4-6-13)17(19-14)20-15(22)10-8-12(2)23-3/h4-7,10H,8-9H2,1-3H3,(H,22,24,26);6-7,12-13H,3-5,8-10H2,1-2H3,(H,21,22,24);2*3,6-7,9,11,13H,2,4-5,8,10H2,1H3,(H,20,21,23);7,9,12-13H,4-6,8,10H2,1-3H3,(H,19,20,22)
• InChIKey: AYZXHOMRERCZDF-UHFFFAOYSA-N
• XLogP: 18.63
• TPSA: 343.54 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 25
• Rotatable Bonds: 25
• Heavy Atoms: 122
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1703.48
LogP ≤ 5	18.63
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	25

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide?

The IUPAC name of N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide (CID 157275152) is N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide.

What is the SMILES notation for N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide?

The canonical SMILES for N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide is CC(C)(C)OCCC(=O)Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cn1.COC(C)CCC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.Cc1ccc2nc(NC(=O)CC3CC(C)(F)C3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCc3ccco3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCc3cccs3)n(C3CCC3)c2n1.

What is the InChIKey of N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide?

The InChIKey is AYZXHOMRERCZDF-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H19ClFN5O2.C18H23FN4O.C18H20N4O2.C18H20N4OS.C17H24N4O2/c1-18(2,3)27-9-8-15(26)24-17-22-12-5-6-13(19)23-16(12)25(17)14-7-4-11(20)10-21-14;1-11-6-7-14-16(20-11)23(13-4-3-5-13)17(21-14)22-15(24)8-12-9-18(2,19)10-12;2*1-12-7-9-15-17(19-12)22(13-4-2-5-13)18(20-15)21-16(23)10-8-14-6-3-11-24-14;1-11-7-9-14-16(18-11)21(13-5-4-6-13)17(19-14)20-15(22)10-8-12(2)23-3/h4-7,10H,8-9H2,1-3H3,(H,22,24,26);6-7,12-13H,3-5,8-10H2,1-2H3,(H,21,22,24);2*3,6-7,9,11,13H,2,4-5,8,10H2,1H3,(H,20,21,23);7,9,12-13H,4-6,8,10H2,1-3H3,(H,19,20,22).

What are the key properties of N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide?

N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide has a molecular weight of 1703.48 g/mol, XLogP of 18.63, 25 rotatable bonds, 5 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(3-fluoro-3-methylcyclobutyl)acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4-methoxypentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-thiophen-2-ylpropanamide is sourced from PubChem (CID 157275152), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).